MRC LMB Seminar Series

Perutz LMB Seminar Series: How our chromosomes are replicated

John Diffley, Associate Research Director, the Francis Crick Institute, London, UK.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Wednesday 26 February 2020, 11:00-12:00

MRC LMB Seminar Series

Milstein LMB Seminar Series: Stem Cells in Silence, Action and Cancer

Elaine Fuchs, Rebecca C. Lancefield Professor Investigator, Howard Hughes Medical Institute .

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Monday 27 January 2020, 11:00-12:00

MRC LMB Seminar Series

LMB Seminar Series: Host factors that shape influenza evolution.

Wendy Barclay.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Friday 06 December 2019, 11:00-12:00

MRC LMB Seminar Series

LMB Seminar Series: Folding and assembly of newly synthesized proteins revealed by ribosome profiling

Bernd Bukau, Center for Molecular Biology of Heidelberg University and German Cancer Research Center.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Thursday 21 November 2019, 16:00-17:00

MRC LMB Seminar Series

LMB Seminar Series - Kendrew Lecture - How a ubiquitin-like protein brings ubiquitylation to life

Brenda Schulman, Director at the Max Planck Institute of Biochemistry.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Thursday 03 October 2019, 10:30-11:30

MRC LMB Seminar Series

LMB Seminar Series - Organelle contact sites: a new layer in the organization of Eukaryotic cells

Benoit Kornmann, Associate professor – Dept. of Biochemistry, Oxford University, and C.W. Maplethorpe Tutorial Fellow in Bio-chemistry – St-Hugh’s College, Oxford University.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Thursday 12 September 2019, 10:30-11:30

MRC LMB Seminar Series

LMB Seminar Series - Antibodies against Ebola and Lassa: A Global Collaboration

Erica Ollmann Saphire, Professor Department of Immunology and Microbiology California Campus.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Tuesday 23 July 2019, 11:00-12:00

MRC LMB Seminar Series

LMB Seminar Series - Francis Crick Lecture - Innovation by Evolution: Bringing New Chemistry to Life

Frances Arnold, California Institute of Technology, Pasadena, U.S.A..

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Thursday 18 July 2019, 16:00-17:00

MRC LMB Seminar Series

What next for your career in science?

Rebecca Aarons, Jenny Gallop, Emma Gleave.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Friday 28 June 2019, 12:00-13:00

MRC LMB Seminar Series

LMB Seminar Series - Structural and mechanistic studies of key components in DNA damage signalling and repair

Xiaodong Zhang.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Tuesday 18 June 2019, 11:00-12:00

MRC LMB Seminar Series

LMB Seminar Series: Folding and assembly of newly synthesized proteins revealed by ribosome profiling

Bernd Bukau, Center for Molecular Biology of Heidelberg University and German Cancer Research Center.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Friday 14 June 2019, 10:30-11:30

MRC LMB Seminar Series

LMB Seminar Series - Towards a mechanistic understanding of cellular processes by cryo-EM

Gaia Pigino, Research Group Leader at the MPI-CBG.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Tuesday 28 May 2019, 11:00-12:00

MRC LMB Seminar Series

LMB Seminar Series - The 100,000 genomes project and beyond

Tim Hubbard, Professor of Bioinformatics & Head of Department, King’s College London.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Thursday 23 May 2019, 16:00-17:00

MRC LMB Seminar Series

LMB Seminar Series: Title tbc

Nieng Yan, Professor of Molecular Biology, Princeton University.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Saturday 18 May 2019, 00:00-00:00

MRC LMB Seminar Series

LMB Seminar Series - Modifications of RNA: their function and role in cancer

Tony Kouzarides, PhD FRS FMedSci, Professor of Cancer Biology, Cancer Research UK Gibb Fellow, Director of the Milner Therapeutics Institute, Member of the Department of Pathology.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Thursday 16 May 2019, 10:30-11:30

MRC LMB Seminar Series

LMB Seminar Series - Synthesis and hydrolysis of the gram-positive cell wall: revisiting old models with new data

David Rudner, Dept. of Microbiology and Immunobiology, Harvard Medical School.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Friday 03 May 2019, 11:00-12:00

MRC LMB Seminar Series

LMB Seminar Series - CryoEM of proton pumping macromolecular machines

John Rubinstein.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Monday 29 April 2019, 11:00-12:00

MRC LMB Seminar Series

LMB Seminar Series - Factors and Functions of ER Membrane Contact Sites

Gia Voeltz PhD, HHMI Investigator and Professor University of Colorado at Boulder.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Wednesday 10 April 2019, 11:00-12:00

MRC LMB Seminar Series

LMB Seminar Series - Pathogen restriction and host specificity: insights from the human pathogen Salmonella Typhi

Jorge Galan, PhD, DVM, Lucille P. Markey Professor of Microbial Pathogenesis and Professor of Cell Biology; Chair, Department of Microbial Pathogenesis.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Friday 05 April 2019, 11:00-12:00

MRC LMB Seminar Series

LMB Seminar Series: Title tbc

Gerry Rubin, Vice President, HHMI, and Executive Director, Janelia Research Campus.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Wednesday 03 April 2019, 00:00-00:00

MRC LMB Seminar Series

LMB Seminar Series: Title tbc

Gerry Rubin, Vice President, HHMI, and Executive Director, Janelia Research Campus.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Wednesday 03 April 2019, 00:00-00:00

MRC LMB Seminar Series

LMB Seminar Series: Title tbc

Julie Ahringer, PhD FMedSci, Director, Wellcome Senior Research Fellow, Professor of Genetics and Genomics, Member of the Department of Genetics.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Wednesday 27 March 2019, 00:00-00:00

MRC LMB Seminar Series

LMB Seminar Series: Title tbc

Julie Ahringer, PhD FMedSci, Director, Wellcome Senior Research Fellow, Professor of Genetics and Genomics, Member of the Department of Genetics.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Wednesday 27 March 2019, 00:00-00:00

MRC LMB Seminar Series

LMB Seminar Series - ANNA KARENINA AND THE GENETICS OF COMPLEX DISEASE: DE NOVO MUTATIONS IN SCHIZOPHRENIA

Mary-Claire King, human geneticist professor, University of Washington.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Thursday 14 March 2019, 10:30-11:30

MRC LMB Seminar Series

LMB Seminar Series - Animating Molecular Biology

Janet Iwasa, Assistant Professor, Biochemistry Department, University of Utah.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Friday 08 March 2019, 11:30-12:30

MRC LMB Seminar Series

LMB Seminar Series Milstein Lecture - Intracellular Membrane Contact Sites, Lipid Dynamics and Neurodegeneration

Pietro De Camilli Departments of Neuroscience and Cell Biology, Howard Hughes Medical Institute, Kavli Institute for Neuroscince, Yale University School of Medicine.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Tuesday 05 March 2019, 16:00-17:00

MRC LMB Seminar Series

LMB Seminar Series - Stem cells, regeneration and organoid cultures

Meritxell Huch, Wellcome Sir Henry Dale Fellow, Member of the Department of Physiology, Development and Neuroscience.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Thursday 28 February 2019, 16:00-17:00

MRC LMB Seminar Series

LMB Seminar Series-Epigenetic inheritance in mammals

Anne Ferguson Smith, Department of Genetics, Wellcome Trust Senior Investigator.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Wednesday 30 January 2019, 11:00-12:00

MRC LMB Seminar Series

LMB Seminar Series-Solving a 3D jigsaw with 1000 pieces - Structure and assembly of the nuclear pore complex

Martin Beck.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Monday 03 December 2018, 11:00-12:00

MRC LMB Seminar Series

Perutz Lecture- How synapses work: Architecture and mechanism of neurotransmitter receptors and transporters

Eric Gouaux.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Thursday 29 November 2018, 16:00-17:00

MRC LMB Seminar Series

LMB Seminar Series-Title to follow

Carrie Partch.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Tuesday 20 November 2018, 11:00-12:00

MRC LMB Seminar Series

Reconstructing Tissue Architecture by Single Cell Genomics

Sarah Teichmann.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Thursday 15 November 2018, 11:00-12:00

MRC LMB Seminar Series

LMB Seminar Series-Mycobacterium tuberculosis infection of host cells in time and space

Max Gutierrez.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Thursday 01 November 2018, 16:00-17:00

MRC LMB Seminar Series

Light Sleep

Gero Miesenboeck.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Wednesday 24 October 2018, 11:00-12:00

MRC LMB Seminar Series

Evidence that sub-cellular oscillators may time and execute organelle biogenesis

Jordan Raff.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Thursday 20 September 2018, 16:00-17:00

MRC LMB Seminar Series

LMB Seminar Series - Kinetochore Structure

Steve Harrison.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Thursday 28 June 2018, 16:00-17:00

MRC LMB Seminar Series

LMB Seminar Series-Title to follow

Michael Hall.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Tuesday 29 May 2018, 16:00-17:00

MRC LMB Seminar Series

LMB Seminar Series-Title to follow

Titia De Lange Rockefeller.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Wednesday 23 May 2018, 11:00-12:00

MRC LMB Seminar Series

Kendrew Lecture-Electron cryo-microscopy

Jacques Dubochet.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Thursday 26 April 2018, 16:00-17:00

MRC LMB Seminar Series

LMB Seminar Series-Title to follow

Lukas Kapitein.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Thursday 15 March 2018, 16:00-17:00

MRC LMB Seminar Series

Kendrew Lecture- Illuminating biology at the nanoscale and systems scale by imaging

Xiaowei Zhuang .

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Monday 15 January 2018, 16:00-17:00

MRC LMB Seminar Series

Localised RNA-based mechanisms underlie neuronal wiring

Christine Holt.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Monday 04 December 2017, 11:00-12:00

MRC LMB Seminar Series

Exploring and Exploiting the Diversity of Secretory Routes in Mammalian Cells

Franck Perez.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Tuesday 28 November 2017, 14:00-15:00

MRC LMB Seminar Series

Genomic and cellular integration of bacterial endosymbionts into host cells

John McCutcheon.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Friday 03 November 2017, 11:00-12:00

MRC LMB Seminar Series

LMB Seminar Series- Stories from the first year of the Central Oxford Structural Microscopy and Imaging Centre - closing in on bacterial protein secretion systems.

Susan Lea.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Monday 02 October 2017, 11:00-12:00

MRC LMB Seminar Series

LMB Seminar Series- How T cells control secretion to optimise target cell killing

Gillian Griffiths.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Tuesday 19 September 2017, 11:00-12:00

MRC LMB Seminar Series

Crick Lecture-The Surprising Chemistry of Non-enzymatic RNA Replication

Jack Szostack, Harvard, USA .

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Thursday 07 September 2017, 16:00-17:00

MRC LMB Seminar Series

Integrated structural biology of gene transcription

Patrick Cramer, Max Planck Institute.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Tuesday 05 September 2017, 16:00-12:00

MRC LMB Seminar Series

LMB Seminar Series-RNA quality control and the nuclear RNA exosome

Chris Lima.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Friday 14 July 2017, 11:00-12:00

MRC LMB Seminar Series

LMB Seminar Series- Title to follow

Andreas Matouschek, Northwestern University, USA.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Monday 03 July 2017, 16:00-17:00

MRC LMB Seminar Series

LMB Seminar Series-DNA Methylation: From stem cell differentiation to chromatin organisation

Margaret Goodell.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Tuesday 20 June 2017, 11:15-12:15

MRC LMB Seminar Series

Charting the response to DNA damage

Dan Durocher, University of Toronto, Faculty of Medicine.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Monday 15 May 2017, 11:00-12:00

MRC LMB Seminar Series

Mulitispectral imaging to uncover the organelle interactome

Jennifer Lippincott-Schwartz, National Institute of Health, Maryland, USA.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Monday 08 May 2017, 16:00-17:00

MRC LMB Seminar Series

Max Perutz Lecture- Antisense transcription and epigenetic switching

Caroline Dean, John Innes Centre, Norwich.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Thursday 27 April 2017, 11:00-12:00

MRC LMB Seminar Series

RNA methylation in development and disease

Michaela Frye, Stem Cell Institute and Department of Genetics, Cambridge.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Friday 24 March 2017, 11:00-12:00

MRC LMB Seminar Series

Membrane proteins - the lipid connection

Carol Robinson, university of Oxford.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Tuesday 07 March 2017, 11:00-12:00

MRC LMB Seminar Series

Milstein Lecture- Molecular Mechanisms of Synaptic Transmission

Thomas Südhof, Department of Molecular and Cellular Physiology, Stanford.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Thursday 09 February 2017, 16:00-17:00

MRC LMB Seminar Series

Comparative studies of intrinsically disordered proteins

Professor Jane Clarke, Department of Chemistry, University of Cambridge .

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Monday 23 January 2017, 11:00-12:00

MRC LMB Seminar Series

Molecular Chaperone Functions in Protein Folding and Quality Control

Ulrich Hartl, max Planck Institute of Biochemistry.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Tuesday 15 November 2016, 12:00-12:00

MRC LMB Seminar Series

Kendrew Lecture- Bacterial Quorum Sensing and its Control

Bonnie Bassler, Princeton University, USA .

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Monday 24 October 2016, 11:00-12:00

MRC LMB Seminar Series

TBC

Amita Sehgal.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Tuesday 27 September 2016, 11:00-12:00

MRC LMB Seminar Series

TBC

Laurence Pearl, Sussex.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Tuesday 12 July 2016, 11:00-12:00

MRC LMB Seminar Series

TBC

Richard Youle.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Friday 01 July 2016, 11:00-12:00

MRC LMB Seminar Series

Pathological vs Reversible Amyloid

David Eisenberg, University of California.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Friday 10 June 2016, 11:00-12:00

MRC LMB Seminar Series

Pathological vs Reversible Amyloid

Prof. David Eisenberg, Dept. Chemistry and Biochemistry, University of California.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Friday 10 June 2016, 11:00-12:00

MRC LMB Seminar Series

Perutz Lecture 2016

Ron Vale, University of California.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Thursday 02 June 2016, 11:00-12:00

MRC LMB Seminar Series

Kendrew lecture- Post-translational regulation of cell signalling

Tony Hunter.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Wednesday 25 May 2016, 15:00-16:00

MRC LMB Seminar Series

Mapping cancer origins

Proffessor Richard Gilbertson, Cancer Research UK, Cambridge.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Tuesday 03 May 2016, 12:00-13:00

MRC LMB Seminar Series

Learning and motivation toggle feed-forward inhibition in the Drosophila mushroom body

Scott Waddell.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Wednesday 27 April 2016, 11:00-12:00

MRC LMB Seminar Series

CRISPR-Cas: origin of adaptive immunity from selfish genetic elements and the evolutionary continuum from Darwin to Lamarck

Eugene Koonin.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Friday 18 March 2016, 11:00-12:00

MRC LMB Seminar Series

Structure of TRP channel by single particle cryo-EM

Yifan Cheng.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Wednesday 16 March 2016, 11:00-12:00

MRC LMB Seminar Series

Cell wall deficient (L-form) bacteria: from cell biology to the origins of life

Jeff Errington.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Thursday 03 March 2016, 16:15-17:15

MRC LMB Seminar Series

mRNA stability is substantially dictated by the action of the ribosome

Rachel Green, Johns Hopkins University, School of Medicine.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Thursday 25 February 2016, 10:30-11:30

MRC LMB Seminar Series

Crick 2016 Lecture-DNA Sequence and the Epigenome Entwined

Adrian Bird.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Tuesday 16 February 2016, 11:30-12:30

MRC LMB Seminar Series

A chemical approach to understanding cell division

Ulrike Eggert.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Tuesday 02 February 2016, 16:15-17:15

MRC LMB Seminar Series

Protein folding homeostasis in the endoplasmic reticulum: tuning a chaperone

David Ron, University of Cambridge.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Friday 29 January 2016, 16:15-17:15

MRC LMB Seminar Series

Milstein Lecture-Phosphoinositide 3-Kinase and Cancer Metabolism

Lewis Cantley, Meyer Cancer Center, Weill Cornell Medicine and New York Presbyterian Hospital, New York.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Monday 14 December 2015, 16:15-17:15

MRC LMB Seminar Series

In the beginning it was dark: Hydrothermal vents and the origin of life (real microbes)

William Martin, Universität Düsseldorf.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Thursday 26 November 2015, 16:15-17:15

MRC LMB Seminar Series

Crick Lecture- The transformative CRISPR-Cas9 genome engineering technology: lessons learned from bacteria

Emmanuelle Charpentier .

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Friday 02 October 2015, 15:15-16:15

MRC LMB Seminar Series

Plasticity of Cancer Cells : Lessons from Glioblastoma

Inder Verma, Salk Institute for Biological Studies.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Friday 04 September 2015, 16:15-17:15

MRC LMB Seminar Series

Persister Cells and the Search for Sterilizing Antibiotics

Kim Lewis.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Monday 15 June 2015, 16:15-17:15

MRC LMB Seminar Series

Structural Mechanisms in the Tyrosine Kinases that Initiate Immunological Signaling

Professor John Kuriyan, University of California.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Thursday 21 May 2015, 16:15-17:15

MRC LMB Seminar Series

Regulation of proteasome function in normal and disease states

Professor Alfred Goldberg, Harvard Medical School.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Friday 15 May 2015, 16:15-17:15

MRC LMB Seminar Series

Chromatin unloading of the replicative DNA helicase during replication and repair

Johannes Walter.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Wednesday 08 April 2015, 16:15-17:15

MRC LMB Seminar Series

Insights from a model of breast tumor heterogeneity

Greg Hannon, CRUK, Cambridge.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Thursday 26 March 2015, 16:15-17:15

MRC LMB Seminar Series

Remodeling of the erythroid proteome

Dan Finley, Harvard.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Tuesday 17 March 2015, 16:15-18:00

MRC LMB Seminar Series

Synthetic Probes for live-cell imaging

Kai Johnsson.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Wednesday 11 March 2015, 16:15-18:00

MRC LMB Seminar Series

Tbc

Jeff Errington.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Tuesday 03 March 2015, 16:15-17:15

MRC LMB Seminar Series

Prion propagation and neurotoxicity

Prof. John Collinge, UCL .

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Thursday 19 February 2015, 16:15-18:00

MRC LMB Cell Biology Seminars

Cambridge Super-Resolution Microscopy Meeting

Dr Hari Shroff, NIH NIBIB,Dr Valentin Nagerl,IINS/Universite de Bordeaux Plus various local speakers .

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Friday 06 February 2015, 10:00-16:00

MRC LMB Seminar Series

Taming a protein destruction machine

Nicolas Thoma, Friedrich Miescher Institute for Biomedical Reearch, Basel, Switzerland.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Thursday 29 January 2015, 16:15-18:00

MRC LMB Seminar Series

Title to be confirmed

David Ron, Cambridge University.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Tuesday 27 January 2015, 16:15-17:15

MRC LMB Seminar Series

Local and Global Regulation of Meiotic Prophase by Post-Translational Protein Modification

Neil Hunter.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Monday 15 December 2014, 16:15-18:00

MRC LMB Seminar Series

Max Perutz Lecture 2014: C. elegans surveillance of conserved cellular components to detect and defend pathogen attacks, real or imagined

Gary Ruvkun, MGH Harvard.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Friday 05 December 2014, 16:15-18:00

MRC LMB Seminar Series

The amazing hepatocyte: master of disguise and adaptation

Dr Markus Grompe.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Monday 10 November 2014, 16:15-18:00

MRC LMB Seminar Series

Genome stability and instability during repair of a broken chromosome

Jim Haber, Director, Rosenstiel Basic Medical Sciences Research Center.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Thursday 06 November 2014, 16:15-18:00

MRC LMB Seminar Series

Crick Lecture 2014: How Aneuploidy Drives Cancer

Stephen Elledge, Gregor Mendel Professor of Genetics, Department of Genetics, Harvard Medical School.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Friday 19 September 2014, 16:15-18:00

MRC LMB Seminar Series

Feedback control of cell division

Andrea Musacchio, Director, Department of Mechanistic Cell Biology, Max-Planck Institute of Molecular Physiology .

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Thursday 18 September 2014, 16:15-18:00

MRC LMB Seminar Series

From static structures to molecular movies: pushing the boundaries of X-ray Crystallography

Wei Yang, NIH, Bethesda, USA.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Friday 05 September 2014, 16:15-18:00

MRC LMB Seminar Series

The Consequences of Whole Genome Duplications

Prof David Pellman, Professor of Cell Biology, Harvard Medical School.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Tuesday 22 July 2014, 16:15-18:00

MRC LMB Seminar Series

Extrinsic regulation of haematopoietic stem cell self

Sean J. Morrison Investigator, Howard Hughes Medical Institute.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Tuesday 15 July 2014, 11:45-13:30

MRC LMB Seminar Series

Milstein Lecture 2014: Unfolded Protein Response in Health and Disease

Peter Walter, University of California, San Francisco .

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Monday 30 June 2014, 16:15-18:00

MRC LMB Seminar Series

The function and execution of RTEL1 activities at vertebrate telomeres

Dr Simon Boulton, DNA damage Response Laboratory, London Research Institute.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Friday 27 June 2014, 16:15-18:00

MRC LMB Seminar Series

Exploring the final events in eukaryotic cell division

Juan Martin-Serrano, Kings College London.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Thursday 26 June 2014, 16:15-18:00

MRC LMB Seminar Series

TBC

Juan Martin-Serrano.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Thursday 26 June 2014, 16:15-18:00

MRC LMB Seminar Series

Engineering strategies for tuning cell surface receptor signalling

K. Christopher Garcia, Stanford University School of Medicine .

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Wednesday 14 May 2014, 16:15-18:00

MRC LMB Seminar Series

Structural basis of protein PARylation-dependent ubiquitination

Rachel Klevit, University of Washington.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Thursday 24 April 2014, 16:15-18:00

MRC LMB Seminar Series

Francis Crick Lecture 2014: Prions Causing Neurodegeneration: A Unifying Etiology and the Quest for Therapeutics

Stanley Prusiner, University of California San Francisco .

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Friday 11 April 2014, 15:00-17:00

MRC LMB Seminar Series

What can NMR tell us about how a virus enters its host cell?

Ad Bax, NIH.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Thursday 10 April 2014, 11:00-12:00

MRC LMB Seminar Series

Building proteins de novo: better, faster, fitter

Dek Woolfson, University of Bristol.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Thursday 27 March 2014, 16:15-18:00

MRC LMB Seminar Series

John Kendrew Lecture 2014: Birth and Future of Multi-Scale Modeling of Macromolecules

Michael Levitt, Standford Unversity.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Tuesday 25 March 2014, 16:15-18:00

MRC LMB Seminar Series

microRNAs, circular RNAs, and micropeptides

Professor Nikolaus Rajewsky, Max Delbrück Center for Molecular Medicine, Berlin.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Monday 24 March 2014, 15:00-16:15

MRC LMB Seminar Series

Type VI Secretion System: structure, function and dynamics of a multicomponent nanomachine that is evolutionarily related to a contractile phage tail

Marek Basler, University of Basel.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Wednesday 26 February 2014, 16:15-18:00

MRC LMB Seminar Series

Lighting up RNA Interactions in Living Cells

David Tollervey, WTCCB, University of Edinburgh.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Monday 10 February 2014, 14:00-15:00

MRC LMB Seminar Series

Feldberg Prize Lecture: The mitochondrial machinery for transport and assembly of proteins

Klaus Pfanner, University of Freiburg.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Thursday 23 January 2014, 16:15-18:00

MRC LMB Seminar Series

Systematic cell biology - Moving beyond text-book schemes

Maya Schuldiner, The Weizmann Insitute of Science.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Thursday 09 January 2014, 14:00-15:00

MRC LMB Seminar Series

GPCRs: From thermostabilisation to X-ray structures and Drug discovery

Fiona Marshall, Heptares Therapeutics.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Thursday 12 December 2013, 16:15-18:00

MRC LMB Seminar Series

Brain Power: Where does it come from and how is it used?

Professor David Attwell, University College London.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Thursday 07 November 2013, 17:00-18:00

MRC LMB Seminar Series

John Kendrew Lecture 2013: Noncoding RNAs: with a viral twist

Joan Steitz, Yale University.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Friday 01 November 2013, 16:15-18:00

MRC LMB Seminar Series

Embracing Complexity: A Drosophila Approach To Cancer Therapeutics

Ross Cagan, Mt. Sinai School of Medicine.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Thursday 31 October 2013, 16:15-18:00

MRC LMB Seminar Series

Can structural studies of intact viruses really be useful in the search for better vaccines and antivirals?

David Stuart, University of Oxford.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Thursday 10 October 2013, 16:15-18:00

MRC LMB Seminar Series

Conformational Conversion in Amyloid Assembly

Sheena Radford, University of Leeds.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Thursday 03 October 2013, 16:15-18:00

MRC LMB Seminar Series

Milstein Lecture 2013: Sorting out protein traffic: Ubiquitin-mediated endocytosis and a membrane protien’s final ESCRT

Scott Emr, Cornell University.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Thursday 26 September 2013, 16:15-18:00

MRC LMB Seminar Series

Innate Immune Sensing and Signaling of Cytosolic DNA and RNA

Zhijan 'James' Chen, University of Texas Southwestern Medical Center.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Tuesday 24 September 2013, 16:15-18:00

MRC LMB Seminar Series

Long-distance organelle transport in the neuron: mechanisms of motor engagement and motor coordination

Erika Holzbaur, University of Pennyslvania.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Thursday 05 September 2013, 16:15-18:00

MRC LMB Seminar Series

The Evolutionary 'Design' of Proteins

Rama Ranganathan, UT Southwestern Medical Centre.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Wednesday 04 September 2013, 11:00-12:00

MRC LMB Seminar Series

Watching Individual Proteins Working on Single Molecules of DNA: from Biophysics to Cancer

Steve Kowalczykowski, University of California.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Friday 09 August 2013, 16:15-18:00

MRC LMB Seminar Series

Biological insights from cryo-EM studies of complex macromolecular assemblies in transcription initiation and microtubule dynamics

Eva Nogales, HHMI University of California Berkely.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Wednesday 24 July 2013, 16:15-18:00

MRC LMB Seminar Series

The impact of systemic inflammation on the brain in health and disease

Hugh Perry, University of Southampton.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Thursday 27 June 2013, 16:15-18:00

MRC LMB Seminar Series

Intrinsic biophysical diversity and connectivity of neuronal circuits

Troy Margrie, NIMR.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Tuesday 11 June 2013, 17:00-18:00

MRC LMB Seminar Series

Direct Selection for Antibodies that Control Cell Fates from Intracellular Combinatorial Antibody Libraries

Professor Richard Lerner, The Scripps Research Institute, USA.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Wednesday 05 June 2013, 12:00-13:00

MRC LMB Seminar Series

Cytoskeletal Control of Leukocyte Chemotaxis

Michael Sixt, IST Austria.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Monday 13 May 2013, 16:15-18:00

MRC LMB Seminar Series

Selective autophagy: when being picky pays of

Ana-Maria Cuervo, Albert Einstein College of Medicine .

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Thursday 02 May 2013, 16:15-18:00

MRC LMB Seminar Series

Max Perutz Lecture: Five ways that viruses use to enter the animal cell

Professor Ari Helenius, ETH Zurich, Switzerland.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Tuesday 30 April 2013, 14:30-15:30

MRC LMB Seminar Series

Machinery for making coated vesicles

Margaret Scott Robinson, CIMR.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Tuesday 16 April 2013, 16:15-18:00

MRC LMB Seminar Series

The genetics of individuals: why would a mutation kill me, but not you?

Ben Lehner, CRG Barcelona.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Tuesday 09 April 2013, 15:00-16:00

MRC LMB Seminar Series

The mammalian circadian timing system: how the brain communicates with the periphery

Ueli Schibler, University of Geneva.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Wednesday 27 March 2013, 12:00-13:00

MRC LMB Seminar Series

Assembly and Dynamics of Uber Complex RNPs

Melissa Moore, University of Massachusetts Medical School.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Monday 03 December 2012, 16:15-18:00

MRC LMB Seminar Series

New insights into the role of the chromatin associated factor ATRX

Doug Higgs, MRC Molecular Haematology Unit, Oxford.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Monday 17 September 2012, 11:30-13:00

MRC LMB Seminar Series

Max Perutz Lecture 2012: Defective DNA strand break repair, genome instability and cancer

Steve West, CRUK LRI - Clare Hall.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Thursday 13 September 2012, 16:15-18:00

MRC LMB Seminar Series

Normal and neoplastic stem cells

Irving Weissman, Stanford School of Medicine.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Wednesday 11 July 2012, 16:15-18:00

MRC LMB Seminar Series

Mechanisms for the Selective Degradation of Ubiquitinated Proteins by the 26S Proteasome

Fred Goldberg, Harvard Medical School.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Friday 22 June 2012, 16:15-18:00

MRC LMB Seminar Series

Shedding light on Ubiquitin Modification in Cancer.

Vishva Dixit, Genentech.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Tuesday 12 June 2012, 16:15-18:00

MRC LMB Seminar Series

The structural and mechanistic basis for Rab cycling and targeting

Roger Goody, MPI Dortmund.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Monday 21 May 2012, 16:15-18:00

MRC LMB Seminar Series

Milstein Lecture 2012: How do we sense microbes? From LPS, TNF, and the TLRs.

Bruce Beutler, UT Southwestern Medical Centre.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Thursday 17 May 2012, 16:15-18:00

MRC LMB Seminar Series

Monitoring protein synthesis one codon at a time through ribosome profiling

Jonathan Weissman, Howard Hughes Medical Institute, UCSF.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Thursday 10 May 2012, 16:15-18:00

MRC LMB Seminar Series

Local Translation at the Synapse

Erin Schuman, Max Planck Institute.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Monday 30 April 2012, 16:15-18:00

MRC LMB Seminar Series

How end binding proteins recognise growing microtubule ends: from molecular structure to network functioning

Thomas Surrey, Cancer Research UK, London Research Institute.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Thursday 26 April 2012, 16:15-18:00

MRC LMB Seminar Series

Molecular mechanisms of complement activation and regulation

Piet Gros, Utrecht University.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Thursday 19 April 2012, 14:00-16:00

MRC LMB Seminar Series

Ubiquitin flips the anaphase switch

David Morgan, UCSF.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Friday 13 April 2012, 16:15-18:00

MRC LMB Seminar Series

John Kendrew Lecture 2012: Harnessing actin dynamics for endocytic trafficking events

David Drubin, Berkeley.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Tuesday 03 April 2012, 16:15-18:00

MRC LMB Seminar Series

A Chemicogenetic approach to DNA repair implicates TORC2 and actin in survival of DNA breaks

Susan Gasser, Friedrich Miescher Institute for Biomedical Research.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Monday 12 March 2012, 16:15-18:00

MRC LMB Seminar Series

Disruptions on the Highways of Cell Communication

Dario Alessi, MRC Protein Phosphorylation Unit, University of Dundee.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Tuesday 06 March 2012, 16:15-18:00

MRC LMB Seminar Series

Structural and Biochemical Mechanisms of Synchronous Synaptic Transmission

James Rothman, Yale University.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Tuesday 21 February 2012, 11:30-18:00

MRC LMB Seminar Series

Crick Lecture 2012: Consequences of Aneuploidy

Angelika Amon, HHMI, MIT.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Wednesday 15 February 2012, 16:15-18:00

MRC LMB Seminar Series

New concepts in host-pathogen interactions: lessons from Listeria

Pascale Cossart, Institute Pasteur, Paris.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Thursday 02 February 2012, 16:15-18:00

MRC LMB Seminar Series

Functions of Dynamin A, Myosin IB and WASH in phagolysosome biogenesis, and the Exocyst in kiss-and-run exocytosis in Dictyostelium

Thierry Soldati, University of Geneva.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Monday 23 January 2012, 16:15-18:00

MRC LMB Seminar Series

Signaling through the ubiquitin system

Wade Harper, Harvard Medical School.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Thursday 15 December 2011, 16:15-18:00

MRC LMB Seminar Series

Structural and Mechanistic Studies of the Anaphase Promoting Complex

David Barford, Institute of Cancer Research.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Thursday 24 November 2011, 16:15-18:00

MRC LMB Seminar Series

The Evolution of Enzyme Mechanisms and Functional Diversity

Janet Thornton, EMBL-EBI.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Tuesday 15 November 2011, 16:15-18:00

MRC LMB Seminar Series

Structural Studies on the Regulation of Protein Kinases: EGFR and CamK-II

John Kuriyan, HHMI, University of California, Berkeley.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Monday 31 October 2011, 16:15-18:00

MRC LMB Seminar Series

Neuronal plasticity: from synapses to the axon initial segment

Juan Burrone, Kings College London.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Friday 28 October 2011, 16:15-18:00

MRC LMB Seminar Series

DNA-dependent protein kinase is a DNA sensor for IRF-3-dependent innate immunity

Geoffrey Smith, Department of Pathology Cambridge.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Thursday 06 October 2011, 16:15-18:00

MRC LMB Seminar Series

mRNA-tRNA translocation intermediates by cryo-EM: a look at the free-energy landscape from a single sample.

Joachim Frank, Columbia University.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Friday 30 September 2011, 16:15-18:00

MRC LMB Seminar Series

Molecular and cellular mechanisms for memory allocation in neuronal networks

Alcino Silva, UCLA.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Friday 16 September 2011, 16:15-18:00

MRC LMB Seminar Series

Genetic dissection of emotion circuits in flies and mice - Francis Crick Lecture 2011

Dr David Anderson, California Institute of Technology, USA.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Friday 09 September 2011, 16:00-18:00

MRC LMB Seminar Series

Self-assembled DNA-nanostructure tools for molecular biophysics

William Shih, Harvard Medical School.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Monday 25 July 2011, 16:15-18:00

MRC LMB Seminar Series

PDBe - Bringing Structure to Biology

Gerard Kleywegt, EMBL-EBI.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Thursday 14 July 2011, 16:15-18:00

MRC LMB Seminar Series

Tuberculosis Treatment Dicta from the Zebrafish

Lalita Ramakrishnan, University of Washington.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Thursday 07 July 2011, 16:15-18:00

MRC LMB Seminar Series

Autoantibodies against NMDA receptors and other neuronal targets: the widening spectrum of antibody-mediated CNS disorders

Angela Vincent, University of Oxford.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Wednesday 22 June 2011, 14:30-16:15

MRC LMB Seminar Series

Exploring and exploiting chromosome repair and segregation mechanisms in cancer

Ashok Venkitaraman, MRC Cancer Cell Unit.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Thursday 16 June 2011, 16:15-18:00

MRC LMB Seminar Series

Visualizing vesicle and virus budding by electron microscopy

John Briggs, EMBL.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Wednesday 01 June 2011, 11:30-13:15

MRC LMB Seminar Series

Genetic Architecture of Leukaemia

Mel Greaves, Institute of Cancer Research.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Thursday 19 May 2011, 16:15-18:00

MRC LMB Seminar Series

Delivery Boy to Reporter: Unusual DNA’s journey through a worm-whole

Yamuna Krishnan, National Centre for Biological Sciences Bangalore.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Tuesday 17 May 2011, 16:15-18:00

MRC LMB Seminar Series

A primer on DNA origami and why molecular biologists might care

Hendrik Dietz, TU Munich.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Thursday 12 May 2011, 16:15-18:00

MRC LMB Seminar Series

Genome-wide analysis of AID activity and AID-mediated translocations in B lymphocytes

Rafael Casellas, NIH.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Friday 06 May 2011, 16:15-18:00

MRC LMB Seminar Series

Feldberg Prize Lecture: Biogenesis of iron-sulfur proteins in eukaryotes

Professor Roland Lill, Philipps University Marburg, Germany.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Friday 15 April 2011, 16:15-18:00

MRC LMB Seminar Series

Controlling Recombination

Simon Boulton, CRUK Clare Hall Laboratories.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Thursday 14 April 2011, 16:15-18:00

MRC LMB Seminar Series

A systematic screen for protein–lipid interactions in Saccharomyces cerevisiae

Anne-Claude Gavin, EMBL.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Tuesday 12 April 2011, 16:15-18:00

MRC LMB Seminar Series

Milstein Lecture 2011: How the endoplasmic reticulum gets into shape

Tom Rapoport, Harvard Medical School.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Thursday 07 April 2011, 16:15-18:00

MRC LMB Seminar Series

The Chemical Biology of Large-Scale Transcriptome Analysis

Kevin Weeks, University of North Carolina.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Wednesday 06 April 2011, 11:30-13:15

MRC LMB Seminar Series

The Cellular Basis for the Cancer-Related Phenomena of Immune Suppression and Cachexia

Doug Fearon.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Thursday 31 March 2011, 16:15-18:00

MRC LMB Seminar Series

The Female Side of Fertilization: Crystal Structure of Vertebrate Sperm Receptor ZP3

Luca Jovine, Karolinska Institute.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Monday 28 March 2011, 16:15-18:00

MRC LMB Seminar Series

The Structural Basis of Ubiquitin Signalling

Cynthia Wolberger, Johns Hopkins University.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Friday 25 March 2011, 16:15-18:00

MRC LMB Seminar Series

Repeat Proteins:Versatile frameworks for understanding and engineering protein structure and function

Lynne Regan, Yale University.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Monday 21 March 2011, 16:15-18:00

MRC LMB Seminar Series

Non-classical means for regulating small G-proteins

Shehab Ismail, Max Planck Institute Dortmund.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Thursday 17 March 2011, 16:15-18:00

MRC LMB Seminar Series

Accuracy of codon reading by transfer RNAs

Måns Ehrenberg.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Friday 18 February 2011, 11:30-13:15

MRC LMB Seminar Series

Transport mechanism and membrane interactions of the cation pumps

Poul Nissen, Aarhus University, Denmark.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Thursday 17 February 2011, 16:15-18:00

MRC LMB Seminar Series

Pre- and postsynaptic NMDA receptors in neocortical synaptic plasticity

Ole Paulsen, Department of Physiology, University of Cambridge.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Tuesday 15 February 2011, 16:15-18:00

MRC LMB Seminar Series

Transcription and R-loops as a source of genome instability

Andrés Aguilera, University of Seville.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Tuesday 08 February 2011, 16:15-18:00

MRC LMB Seminar Series

In vitro and in vivo single molecule studies of chromosome replication and segregation

David Sherratt, University of Oxford.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Monday 07 February 2011, 16:15-18:00

MRC LMB Seminar Series

Genetic approaches to understand and manipulate retinal circuit function

Botond Roska, Friedrich Miescher Institute for Biomedical Research.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Thursday 03 February 2011, 16:15-18:00

MRC LMB Seminar Series

Off-the-shelf models of chromosomal translocations and using antibody fragments as cancer drug surrogates

Terry Rabbitts, Leeds Institute of Molecular Medicine.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Monday 31 January 2011, 16:15-18:00

MRC LMB Seminar Series

Crystal structures of bacterial and yeast ribosomes

Marat Yusupov, Illkirch, France.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Thursday 27 January 2011, 16:15-18:00

MRC LMB Seminar Series

Interactions of Cancer Stem Cells with their Niches are Essential for Breast Cancer Metastasis

Dr Joerg Huelsken, Swiss Federal Univerity of Technology, Lausanne, Switzerland.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Tuesday 25 January 2011, 16:15-18:00

MRC LMB Seminar Series

The mechanism of retroviral DNA integration through X-ray structures of its key intermediates

Peter Cherepanov, Faculty of Medicine, Imperial College.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Tuesday 11 January 2011, 16:15-18:00

MRC LMB Seminar Series

Structural biology of bacterial secretion systems

Gabriel Waksman.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Monday 13 December 2010, 16:15-18:00

MRC LMB Seminar Series

Protein folding homeostasis and prion-like propagation of protein aggregation in neurodegenerative disease

Ron Kopito, Stanford University, CA USA.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Friday 10 December 2010, 14:15-16:00

MRC LMB Seminar Series

Structural insights into the process of co-translational targeting of membrane proteins and translation initiation in eukaryotes

Nenad Ban.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Monday 06 December 2010, 16:15-18:00

MRC LMB Seminar Series

Femtosecond Membrane-Protein Nanodiffraction using a Hard X-Ray Laser

John Spence, Arizona State University.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Tuesday 23 November 2010, 16:15-18:00

MRC LMB Seminar Series

Dehydrated but unharmed? – the mass spectrometry of protein complexes

Professor Carol Robinson, Department of Chemistry, Oxford University.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Monday 22 November 2010, 16:15-18:00

MRC LMB Seminar Series

Deconstructin oncogenesis and tumour suppression to find the best cancer drug targets

Gerard Evan, Department of Biochemistry, Unversity of Cambridge.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Thursday 18 November 2010, 16:15-18:00

MRC LMB Seminar Series

Regulation of microRNA biogenesis and function

Javier F Caceres, MRC Human Genetics Unit, Edinburgh.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Monday 15 November 2010, 16:15-18:00

MRC LMB Seminar Series

Nucleocytoplasmic Transport Machinery and Pathways: Cell Cycle Regulation and Stress Response

Naoko Imamoto, Cellular Dynamics Laboratory, RIKEN ASI.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Monday 15 November 2010, 14:00-16:00

MRC LMB Seminar Series

Mitosis and Meiosis in live mammalian cells: From genome wide RNAi profiling to homologous chromosome segregation

Jan Ellenberg, EMBL, Heidelberg, Germany.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Friday 05 November 2010, 14:15-16:00

MRC LMB Seminar Series

Ion channels: Structure, modulation, and unconventional approaches

Dan Minor, University of California, San Francisco, USA.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Monday 25 October 2010, 16:15-18:00

MRC LMB Seminar Series

Role of intrinsic Flexibility in Protein Regulatory Mechanisms

Richard Kriwacki, St Jude's Children's Research Hospital, USA.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Thursday 07 October 2010, 16:15-18:00

MRC LMB Seminar Series

Small Molecules and Light as Tools for the Regulation of Biological Proceeses

Alex Deiters, North Carolina State University, USA.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Wednesday 29 September 2010, 16:15-18:00

MRC LMB Seminar Series

Connecting transcription with mRNA processing and chromatin

Steve Buratowski Harvard Medical School, USA.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Tuesday 21 September 2010, 16:15-18:00

MRC LMB Seminar Series

Autophagy: molecular machinery and role in diseases

Tamotsu Yoshimori Osaka University, Japan.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Monday 13 September 2010, 12:15-13:30

MRC LMB Seminar Series

Gene Regulatory Network Guidance of Cellular Identity Choice: Stem Cells to T Cell

Ellen Rothenberg California Institute of Technology, USA.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Monday 13 September 2010, 11:00-12:00

MRC LMB Seminar Series

Assembly and function of K11-linked ubiquitin chains

Michael Rape, University of California, Berkeley, USA.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Wednesday 08 September 2010, 11:15-13:30

MRC LMB Seminar Series

The genomic code for nucleosome positioning

Jon Widom, Department of Biochemistry, Northwestern University, USA.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Thursday 20 May 2010, 16:15-18:00

MRC LMB Seminar Series

The T cells that nature didn't select

Bent Jakobsen, Immunocore Ltd, Abingdon, Oxon.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Monday 10 May 2010, 16:15-18:00

MRC LMB Seminar Series

Epigenetic reprogramming in transplanted nuclei

John Gurdon, Gurdon Institute, University of Cambridge.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Thursday 06 May 2010, 16:15-18:00

MRC LMB Seminar Series

Gene punctuation: multiple roles of transcriptional termination in regulating eukaryotic gene expression

Nick Proudfoot, University of Oxford.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Monday 26 April 2010, 16:15-18:00

MRC LMB Seminar Series

Some like it hot: nucleosomes mediate temperature sensing

Philip Wigge, John Innes Centre, Norwich.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Thursday 01 April 2010, 11:15-13:00

MRC LMB Seminar Series

Unfolding pathways of endoplasmic reticulum stress response and apoptosis in Drosophilia

Don Ryoo, New York Univeristy School of Medicine, USA.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Monday 29 March 2010, 11:15-13:00

MRC LMB Seminar Series

The evolution of long ncRNAs and Prdm9, a special gene

Chris Pointing, University of Oxford.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Thursday 18 March 2010, 16:15-18:00

MRC LMB Seminar Series

TBC

Venki Murthy, Dept. of Molecular and Cellular Biology at Harvard University.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Thursday 21 January 2010, 16:15-18:00

MRC LMB Seminar Series

A Ubiquitin-winnowing machine: Is there ubiquitin chain selection upstream to the proteasome?

Michael Glickman, Technion Haifa, Israel.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Thursday 14 January 2010, 16:15-18:00

MRC LMB Seminar Series

New genes involved in deafness from large-scale mouse screens

Karen Steel.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Thursday 03 December 2009, 16:15-18:00

MRC LMB Seminar Series

On the origin of RNA and peptide synthesis: clues from biology and prebiotic chemistry

John D Sutherland, Manchester.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Friday 27 November 2009, 16:15-18:00

MRC LMB Seminar Series

Role of PRG-1 (plasticity related gene-1) in glutamatergic transmission

Dietmar Schmitz, Charité, Berlin.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Wednesday 18 November 2009, 16:15-18:00

MRC LMB Seminar Series

Mass Spectrometry and it's Role in Structural Biology

Carol V Robinson.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Tuesday 10 November 2009, 16:15-16:00

MRC LMB Seminar Series

Mapping metazoan gene regulatory networks to understand transcription factor function in health and disease

Bart Deplancke, Institute of Bio-engineering, School of Life Sciences, Swiss Federal Institute of Technology in Lausanne (EPFL).

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Tuesday 29 September 2009, 10:30-12:30

MRC LMB Seminar Series

Cellular quality control of protein aggregates by chaperones

Bernd Bukau, ZMBH, Universität Heidelberg, Germany.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Friday 25 September 2009, 12:00-14:30

MRC LMB Seminar Series

Neuronal Differentiation and Mechanosensory Transduction in C. elegans.

Marty Chalfie, Columbia University, USA.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Thursday 24 September 2009, 16:15-17:30

MRC LMB Seminar Series

Biochemical Society Early Career Lecture: Structure and specificity of deubiquitinases

David Komander, LMB.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Monday 14 September 2009, 16:15-17:30

MRC LMB Seminar Series

G protein signaling in photoreceptors

Vadim Arshavsky, Duke University, USA.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Tuesday 08 September 2009, 16:15-17:30

MRC LMB Seminar Series

Genes and Cells that Influence the Lifespan of C. elegans

Cynthia Kenyon, University of California San Francisco.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Thursday 09 July 2009, 16:15-17:30

MRC LMB Seminar Series

How transcription factors deal with nucleosomes

Mark Ptashne, Memorial Sloan-Kettering Cancer Centre, New York.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Thursday 04 June 2009, 16:15-17:30

MRC LMB Seminar Series

A Mystery Solved: Why Lis1 ans NudE are important for dynein mediated nuclear migration

Dr Steven Gross-University of California, Irvine..

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Thursday 21 May 2009, 16:15-17:30

MRC LMB Seminar Series

Probing dynamic assembly and conformational changes of GPCR signalling complexes using bioluminescence and fluorescence resonance energy transfer approaches.

Professor Michel Bouvier-Institute for Reseach in Immunology and Cancer, Université de Montréal.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Friday 01 May 2009, 14:30-16:30

MRC LMB Seminar Series

Genetic analysis of Parkinson disease; from fruit flies to moving mitochondria

Alex Whitworth-Department of Biomedical Science, The University of Sheffield.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Thursday 30 April 2009, 12:00-14:00

MRC LMB Seminar Series

Nanotubes and Synapses in Immune Cell Biology

Professor Daniel Davis, Imperial College London.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Thursday 23 April 2009, 11:00-14:00

MRC LMB Seminar Series

X-ray tomography generates 3-D views of whole cells at better than 50 nm resolution

Dr Carolyn Larabell, University of California.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Tuesday 31 March 2009, 16:15-18:00

MRC LMB Seminar Series

Modern synthetic biology. Darwin from the atom up

Professor Steven A Benner.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Friday 27 March 2009, 16:15-17:30

MRC LMB Seminar Series

The Nature and Chemical Biology of G-quadruplex Nucleic Acids

Professor Shankar Balasubramanian.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Thursday 26 March 2009, 16:15-17:30

MRC LMB Seminar Series

Regulators of synapse formation in C. elegans

Professor Kang Shen.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Friday 13 March 2009, 14:00-17:30

MRC LMB Seminar Series

New work with RNase P: regulation in HeLa cells and therapeutic tools

Professor Sidney Altman.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Thursday 12 March 2009, 16:15-17:30

MRC LMB Seminar Series

Activation of Protein Kinases by the HSP90 Molecular Chaperone System

Dr Laurence Pearl.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Tuesday 24 February 2009, 16:15-17:30

MRC LMB Seminar Series

From cell mechanics to tissue morphogenesis

Dr Thomas Lecuit.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Thursday 19 February 2009, 16:15-17:30

MRC LMB Seminar Series

Disease, development, evolution and environment: insights from eyes

Professor Veronica van Heyningen.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Tuesday 10 February 2009, 16:15-17:30

MRC LMB Seminar Series

Indecent exposure: replication, sex and survival with unprotected telomeres

Dr Julia Cooper.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Thursday 05 February 2009, 16:15-17:30

MRC LMB Seminar Series

Multidimensional proteomics and genetic analysis reveal condensin's function in vertebrate mitotic chromosomes

Dr Bill Earnshaw.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Tuesday 27 January 2009, 16:15-17:30

MRC LMB Seminar Series

Nuclear architecture in zebrafish: Cajal bodies are required for life and splicing during embryogenesis

Dr Karla Neugebauer.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Monday 26 January 2009, 16:15-17:30

MRC LMB Seminar Series

IgH Class switching, Translocations, and Lymphoma

Professor Fred Alt.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Monday 15 December 2008, 11:00-12:15

MRC LMB Seminar Series

DNA sequence dynamics under nucleosome constraint: Form Follows Function Follows Form?

Professor Andrew Fire.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Friday 12 December 2008, 11:15-12:30

MRC LMB Seminar Series

Love at first light

Professor Gero Miesenboeck.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Tuesday 09 December 2008, 16:15-17:30

MRC LMB Seminar Series

Insights into mechanosensitive ion channels

Professor Jim Naismith.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Monday 24 November 2008, 16:15-17:30

MRC LMB Seminar Series

CANCELLED - Transcriptional regulation by the Polycomb system

TALK CANCELLED DUE TO ILLNESS.

Dr Juerg Mueller.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Friday 21 November 2008, 16:15-17:30

MRC LMB Seminar Series

Cancerous microRNAs and regulatory binding proteins

Dr Reuven Agami.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Thursday 20 November 2008, 16:15-17:30

MRC LMB Seminar Series

Thinking Small: Fragment-Based Drug Design

Dr Glyn Williams.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Thursday 06 November 2008, 16:15-17:30

MRC LMB Seminar Series

Identification of 20 novel breast cancer fusion genes using genome-wide massively parallel paired-end sequencing

Talk preceded by free tea and plaque presentation in the MPLT foyer at 3.45 pm

Dr Philip Stephens.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Tuesday 04 November 2008, 16:15-17:30

MRC LMB Seminar Series

Tackling an old enemy: new ways to target RNA

Dr Gabriele Varani.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Friday 10 October 2008, 14:30-15:45

MRC LMB Seminar Series

eIF3a cooperates with sequences 5' of uORF1 to promote resumption of scanning by post-termination ribosomes for reinitiation on GCN4 mRNA

Dr Leos Valasek.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Monday 06 October 2008, 16:15-17:30

MRC LMB Seminar Series

SNAREs, Synaptotagmin, and Fusion Pores

Professor Meyer Jackson.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Thursday 25 September 2008, 16:15-17:30

MRC LMB Seminar Series

The structure of tubulin and the control of microtubule assembly

Professor Marcell Knossow.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Tuesday 16 September 2008, 16:15-17:30

MRC LMB Seminar Series

Connectomics in the developing nervous system

Professor Jeff W Lichtman.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Friday 22 August 2008, 11:15-12:30

MRC LMB Seminar Series

Novel molecular switches for optical research on living cells

Dr Gerard Marriott.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Thursday 10 July 2008, 16:15-17:30

MRC LMB Seminar Series

Understanding and controlling cell death

Professor Jim Wells.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Friday 04 July 2008, 16:15-17:30

MRC LMB Seminar Series

Structural analysis of cells and viruses at molecular resolution with 3D electron microscopy

Dr Sriram Subramaniam.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Wednesday 25 June 2008, 16:15-17:30

MRC LMB Seminar Series

Function of diverse transcriptional coactivators in animal cells

Professor Robert G Roeder.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Monday 09 June 2008, 16:15-17:30

MRC LMB Seminar Series

Transcription factories and nuclear organization of the genome

Dr Peter Fraser.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Tuesday 06 May 2008, 16:15-17:30

MRC LMB Seminar Series

A "molecular sled" activates the adenovirus proteinase and carries it along tens of thousands of base pairs of viral DNA via one-dimensional diffusion to locate its substrates

Dr Walter Mangel.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Thursday 01 May 2008, 16:15-17:30

MRC LMB Seminar Series

The interplay between phosphorylation and polyubiquitinatioan in regulating the innate immune system

Professor Sir Philip Cohen.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Thursday 24 April 2008, 16:15-17:30

MRC LMB Seminar Series

Using microfluidics to ask other peoples questions in biology

Dr Mark Tracey.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Friday 11 April 2008, 16:15-17:30

MRC LMB Seminar Series

The organization and topology of the bacterial nucleoid: steps towards a holistic theory of transcriptional regulation

Professor Georgi Muskhelishvili.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Thursday 10 April 2008, 16:15-17:30

MRC LMB Seminar Series

Using Chemical Tools to Elucidate the Molecular Mechanism of Malaria Infection and Develop a Malaria Vaccine

Professor Peter Seeberger.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Tuesday 08 April 2008, 10:30-11:45

MRC LMB Seminar Series

A glimpse into the atomic structure of plant photosystem I - 3.5 billion years of perfection

Professor Nathan Nelson.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Thursday 03 April 2008, 16:15-17:30

MRC LMB Seminar Series

Targeting the lipid kinases

Dr Zachary Knight.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Tuesday 18 March 2008, 16:15-17:30

MRC LMB Seminar Series

Structure and Dynamics of the Human beta 2 Adrenergic Receptor

Professor brian Kobilka.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Friday 14 March 2008, 14:15-15:30

MRC LMB Seminar Series

How do miRNAs silence gene expression?

Dr Elisa Izaurralde, Department of Biochemistry, Max-Planck-Institute for Developmental Biology.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Friday 07 March 2008, 14:15-15:30

MRC LMB Seminar Series

Centrosomal delivery of secretory granules

Prof Gillian Griffiths, Cambridge Institute for Medical Research.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Thursday 06 March 2008, 16:15-17:30

MRC LMB Seminar Series

Autophagy and neurodegenerative diseases

Prof David Rubinsztein, Cambridge Institute for Medical Research.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Thursday 28 February 2008, 16:15-17:30

MRC LMB Seminar Series

RNA catalysis: sophisticated biochemistry by a simple biopolymer

Dr Adrian Ferre D'Amare, Fred Hutchinson Cancer Research Center, Seattle.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Monday 25 February 2008, 16:15-17:30

MRC LMB Seminar Series

Towards in vivo molecular automata

Dr Yaakov Benenson, Bauer Fellow, FAS Center for Systems Biology, Harvad University.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Thursday 07 February 2008, 16:15-17:30

MRC LMB Seminar Series

Feldberg Foundation Prize Lecture: "Formation of ribonucleoprotein particles and their nuclear export through nuclear pore complexes

Dr Ed Hurt, University of Heidelberg.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Thursday 31 January 2008, 16:15-17:30

MRC LMB Seminar Series

Turning LMB Science into a Half a Billion Dollar Business

Dr Ian Tomlinson.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Thursday 13 December 2007, 16:15-17:30

MRC LMB Seminar Series

ENCODE: Understanding our genome

Dr Ewan Birney.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Tuesday 11 December 2007, 16:15-17:30

MRC LMB Seminar Series

Microfluidics in Biology

Dr Ronny van't Oever.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Friday 23 November 2007, 16:15-17:30

MRC LMB Seminar Series

The DNA damage problem and its impact on cancer and aging

Dr Jan Hoeijmakers.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Tuesday 20 November 2007, 16:15-17:30

MRC LMB Seminar Series

Organisation of membrane transport by microtubule motors and plus tracking proteins

Dr Anna Akhmanova.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Tuesday 13 November 2007, 16:15-17:30

MRC LMB Seminar Series

RNA Structure, Catalysis and the Origin of Lfe

Dr Bill Scott.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Tuesday 06 November 2007, 16:15-17:30

MRC LMB Seminar Series

Structural basis of interative fatty acid synthesis catalyzed by giant multienzyme complexes

Dr Nenad Ban.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Thursday 01 November 2007, 16:15-17:30

MRC LMB Seminar Series

Silence of the Genes: DNA methylation in cancer

Dr Howard Cedar.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Thursday 01 November 2007, 11:15-12:30

MRC LMB Seminar Series

Genomics: From Humans to the Environment

Dr Craig Venter.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Friday 26 October 2007, 11:00-12:30

MRC LMB Seminar Series

Regulation of the proteasome and the dynamics of multiubiquitin chains

Prof Dan Finley, Dept. of Cell Biology, Harvard Medical School, Boston, USA.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Friday 21 September 2007, 12:00-13:30

MRC LMB Seminar Series

What structural studies tell us about amyloids and prions

Professor David Eisenberg, HHMI?UCLA-DOE Institute for Genomics and Proteomics, Los Angeles, USA.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Tuesday 04 September 2007, 16:15-17:30

MRC LMB Seminar Series

Searching for biological function and evolutionary trajectories in the protein universer

Dr L Aravind, National Center for Biotechnology Information, NIH, USA.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Wednesday 08 August 2007, 16:15-17:30

Proteins, Genomes & Computers

Translational regulation

http://www.mrc-lmb.cam.ac.uk/tcbsymposium/

Christine Vogel, UT Austin, TX, USA.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Saturday 07 July 2007, 17:00-17:30

Proteins, Genomes & Computers

From superfamilies to families

http://www.mrc-lmb.cam.ac.uk/tcbsymposium/

Julian Gough, Bristol University, UK.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Saturday 07 July 2007, 16:30-17:00

Proteins, Genomes & Computers

The relation between sequence and function divergence in genomes

http://www.mrc-lmb.cam.ac.uk/tcbsymposium/

Sarah Teichmann, MRC Laboratory of Molecular Biology, Cambridge.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Saturday 07 July 2007, 16:00-16:30

Proteins, Genomes & Computers

Pfam: 1000 families (and counting) for the molecular biologist

http://www.mrc-lmb.cam.ac.uk/tcbsymposium/

Alex Bateman, Sanger Institute, Cambridge.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Saturday 07 July 2007, 15:00-15:30

Proteins, Genomes & Computers

Ultraconserved nonsense

http://www.mrc-lmb.cam.ac.uk/tcbsymposium/

Steven Brenner, Berkeley, USA.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Saturday 07 July 2007, 14:30-15:30

Proteins, Genomes & Computers

Principles and classification of protein structure

http://www.mrc-lmb.cam.ac.uk/tcbsymposium/

Alexey Murzin, MRC Laboratory of Molecular Biology, Cambridge.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Saturday 07 July 2007, 14:00-14:30

Proteins, Genomes & Computers

Predicting RNA genes

http://www.mrc-lmb.cam.ac.uk/tcbsymposium/

Sean Eddy, Janelia Farm, USA.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Saturday 07 July 2007, 12:00-12:30

Proteins, Genomes & Computers

About Sandwich Proteins, their sequences and structures, and about many other things

http://www.mrc-lmb.cam.ac.uk/tcbsymposium/

Alex Kister, Rutgers, USA.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Saturday 07 July 2007, 11:30-12:00

Proteins, Genomes & Computers

Human pseudogenes

one-day computational biology meeting

Mark Gerstein, Yale University.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Saturday 07 July 2007, 11:00-11:30

Proteins, Genomes & Computers

Protein folding: a theoretical view

one-day computational biology meeting

Alexeii Finkelstein, Pushchino, Russia.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Saturday 07 July 2007, 10:00-10:30

Proteins, Genomes & Computers

The globins: we thought we understood them

one-day computational biology meeting

Arthur Lesk, Penn State University.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Saturday 07 July 2007, 09:30-10:00

Proteins, Genomes & Computers

Cam, Cals and Capri

one-day computational biology meeting

Joel Janin, LEBS, Gif-sur-Yvette, France.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Saturday 07 July 2007, 09:00-09:30

MRC LMB Seminar Series

HIV assembly - is it the plasma membrane after all?

Mark Marsh, MRC LMCB.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Tuesday 03 July 2007, 16:15-17:30

MRC LMB Seminar Series

Organising Microtubules in Space and Time

Damien Brunner, EMBL Heidelberg.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Tuesday 19 June 2007, 16:15-17:30

MRC LMB Seminar Series

Evolution of the Pathological process underlying sporadic Parkinson's Disease

Heiko Braak, University of Frankfurt.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Monday 04 June 2007, 16:15-17:30

MRC LMB Seminar Series

Mechanisms of epigenetic reprogramming in mammalian development

Wolf Reik, Babraham Institute, Cambridge.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Thursday 31 May 2007, 16:15-17:30

MRC LMB Seminar Series

Structural Analysis of Glutamate receptor gating and allosteric regulation

Mark Mayer, NIH, Bethesda.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Tuesday 22 May 2007, 16:15-17:30

MRC LMB Seminar Series

Centrosomes: organizers of cell division in C.elegans embryos

Tony Hyman, Max Planck Institute of Molecular Cell Biology and Genetics, Dresden.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Thursday 17 May 2007, 16:15-17:30

MRC LMB Seminar Series

Optogenetic control of neuronal function, and molecular analysis of nicotinic acetylcholine receptor associated proteins in Caenorhabditis elegens

Alex Gottschalk, Universit of Frankfurt.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Wednesday 16 May 2007, 16:15-17:30

MRC LMB Seminar Series

Neural Processing of Optic Flow in the Fly

Alex Borst, MPI of Neurobiology, Martinsried.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Thursday 10 May 2007, 16:15-17:30

MRC LMB Seminar Series

LepA, one of the most conserved proteins known and present in all bacteria and mitochondriae, is a ribosomal elongation factor with a new function

Knud Nierhaus, Max Planck Institute for Molecular Genetics, Berlin.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Tuesday 24 April 2007, 16:15-17:30

MRC LMB Seminar Series

The molecular mechanics of eukaryotic translation initiation

Jon Lorsch, John Hopkins, Baltimore.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Thursday 12 April 2007, 16:15-17:30

MRC LMB Seminar Series

Ubiquitin signalling networks

Ivan Dikic, Goethe University Medical School, Frankfurt.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Thursday 29 March 2007, 16:15-17:30

MRC LMB Seminar Series

Receptor-recruitment by a natively disordered protein

Colin Kleanthous, University of York.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Wednesday 21 March 2007, 14:15-15:30

MRC LMB Seminar Series

Quantitative proteomics of organelles of the early secretory pathway

John Bergeron, McGill University, Montreal, Canada.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Tuesday 13 March 2007, 16:15-17:30

MRC LMB Seminar Series

Structural variation in the human genome

Matthew Hurles, Wellcome Trust Sanger Institute, Cambridge.

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Thursday 08 March 2007, 16:15-17:30

Imaging and Mathematics

Breaking the Resolution Limit in Light Microscopy

Rainer Heintzmann (King's College London).

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Wednesday 07 June 2006, 16:00-17:00

Imaging and Mathematics

New Developments in Optical Imaging

Brad Amos (MRC-LMB).

Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

Wednesday 03 May 2006, 16:00-17:00