University of Cambridge > > MRC LMB Seminar Series > Structural and Biochemical Mechanisms of Synchronous Synaptic Transmission

Structural and Biochemical Mechanisms of Synchronous Synaptic Transmission

Add to your list(s) Download to your calendar using vCal

If you have a question about this talk, please contact Scientific Meetings Co-ordinator.

SNAR Es fuse cellular membranes, including synaptic vesicles with pre-synaptic plasma membranes to enable synaptic transmission. SNAR Es fuse membranes automatically, so a clamp is needed to prevent premature transmitter release, provided by the protein complexin. Recent studies have established the structural and biochemical mechanism of clamping by complexin involving a co-operative array of partly zippered SNAR Epins whose disolution can explain the syncronicity of transmitter release when the calcium sensor, synaptotagmin, perturbs the array.

This talk is part of the MRC LMB Seminar Series series.

Tell a friend about this talk:

This talk is included in these lists:

Note that ex-directory lists are not shown.


© 2006-2024, University of Cambridge. Contact Us | Help and Documentation | Privacy and Publicity