University of Cambridge > Talks.cam > MRC LMB Seminar Series > Systematic cell biology - Moving beyond text-book schemes

  Browse A-Z

Log in

Cambridge users (raven)details Other usersdetails No account?details

Information on

Subscribing to talksdetails Finding a talkdetails Adding a talkdetails Disseminating talksdetails Help and Documentationdetails

Systematic cell biology - Moving beyond text-book schemes

Add to your list(s) Download to your calendar using vCal

If you have a question about this talk, please contact Scientific Meetings Co-ordinator.

Cells are highly complex systems and as such require complex tools to study. Indeed, in the past years new tools have revolutionized our ability to move from the study of single genes to genomes and from single RNA molecules to global expression profiles. However, the main mediators of cellular function are proteins and therefore a true understanding of how proteins mature and target to their site of function is an additional, and essential, layer for understanding cell biology at a molecular level. For many years the pathways for protein biogenesis were studied for single proteins that were established as “model proteins” giving rise to simplified textbook schemes of cellular function. Proteins that did not use the known pathways were categorized as “exceptions to the rule” and often the pathways mediating their maturation were never uncovered. In the talk I will discuss new tools for assessing the biogenetic requirements of organelle proteins in the cell by combining toolsets for systematic proteomic studies in Saccharomyces cerevisiae. These methods rely on the ability to rapidly generate tailor made collections of mutants and screen them via a fully automated high content screening platform. This approach should enable a new light to be shed on basic questions in cell biology, thus enabling a better understanding of the complex mechanisms that guide organelle biology in yeast.

This talk is part of the MRC LMB Seminar Series series.

Tell a friend about this talk:

This talk is included in these lists:

Note that ex-directory lists are not shown.

Other lists

How representing multiple objects (and features) as an ensemble enhances higher-level visual cognition OWASP (Application Security) Cambridge Chapter Events & Conferences Electronics Knowledge Transfer Network Festival of the Annunciation, Fitzwilliam Museum Type the title of a new list here Engineering Department Geotechnical Research Seminars

Other talks

Sneks long balus Roland the Hero Smuts, bunts and ergots Localization and chiral splitting in scattering amplitudes Developing an optimisation algorithm to supervise active learning in drug discovery Cycloadditions via TMM-Pd Intermediates: New Strategies for Asymmetric Induction and Total Synthesis Coin Betting for Backprop without Learning Rates and More Graded linearisations for linear algebraic group actions Formation and disease relevance of axonal endoplasmic reticulum, a "neuron within a neuron”. 'Cryptocurrency and BLOCKCHAIN – PAST, PRESENT AND FUTURE' Regulators of Muscle Stem Cell Fate and Function
 

© 2006-2024 Talks.cam, University of Cambridge. Contact Us | Help and Documentation | Privacy and Publicity