University of Cambridge > Talks.cam > Statistics > New Approaches for Inference on Optimal Treatment Regimes

  Browse A-Z

Log in

Cambridge users (raven)details Other usersdetails No account?details

Information on

Subscribing to talksdetails Finding a talkdetails Adding a talkdetails Disseminating talksdetails Help and Documentationdetails

New Approaches for Inference on Optimal Treatment Regimes

Add to your list(s) Download to your calendar using vCal

If you have a question about this talk, please contact Qingyuan Zhao.

Finding the optimal treatment regime (or a series of sequential treatment regimes) based on individual characteristics has important applications in precision medicine. We propose two new approaches to quantify uncertainty in optimal treatment regime estimation. First, we consider inference in the model-free setting, which does not require to specify an outcome regression model. Existing model-free estimators for optimal treatment regimes are usually not suitable for the purpose of inference, because they either have nonstandard asymptotic distributions or do not necessarily guarantee consistent estimation of the parameter indexing the Bayes rule due to the use of surrogate loss. We study a smoothed robust estimator that directly targets the parameter corresponding to the Bayes decision rule for optimal treatment regimes estimation. We verify that a resampling procedure provides asymptotically accurate inference for both the parameter indexing the optimal treatment regime and the optimal value function. Next, we consider the high-dimensional setting and propose a semiparametric model assisted approach for simultaneous inference. Simulations results and real data examples are used for illustration. (Joint work with Yunan Wu and Haoda Fu)

This talk is part of the Statistics series.

Tell a friend about this talk:

This talk is included in these lists:

Note that ex-directory lists are not shown.

Other lists

Molecules and genes in Alzheimer's Graduate Women's Network Wizkid

Other talks

Histories of Capitalism: the View from Offshore Dissecting the neural circuits underlying prefrontal regulation of reward and threat responsivity in a primate Bacterial condensates under stress Next-Generation Solar Photovoltaics The Regions, Economy and Society in the Post-Covid World
 

© 2006-2024 Talks.cam, University of Cambridge. Contact Us | Help and Documentation | Privacy and Publicity