Computational Neuroscience Journal Club

Add to your list(s) Download to your calendar using vCal

• Rodrigo Echeveste (CBL)
• Tuesday 03 October 2017, 15:00-16:00
• Cambridge University Engineering Department, CBL, BE4-38 (http://learning.eng.cam.ac.uk/Public/Directions).

If you have a question about this talk, please contact Rodrigo Echeveste.

Rodrigo Echeveste will cover:

• Behavioral time scale synaptic plasticity underlies CA1 place fields
• K.C. Bittner, A.D. Milstein, C. Grienberger, S. Romani, and J. C. Magee
• Science (September 2017)
• http://science.sciencemag.org/content/357/6355/1033

Abstract: Learning is primarily mediated by activity-dependent modifications of synaptic strength within neuronal circuits. We discovered that place fields in hippocampal area CA1 are produced by a synaptic potentiation notably different from Hebbian plasticity. Place fields could be produced in vivo in a single trial by potentiation of input that arrived seconds before and after complex spiking. The potentiated synaptic input was not initially coincident with action potentials or depolarization. This rule, named behavioral time scale synaptic plasticity, abruptly modifies inputs that were neither causal nor close in time to postsynaptic activation. In slices, five pairings of subthreshold presynaptic activity and calcium (Ca2+) plateau potentials produced a large potentiation with an asymmetric seconds-long time course. This plasticity efficiently stores entire behavioral sequences within synaptic weights to produce predictive place cell activity.

This talk is part of the Computational Neuroscience series.

This talk is included in these lists:

• All Talks (aka the CURE list)
• Biology
• Biology
• CBL important
• CamBridgeSens
• Cambridge Centre for Data-Driven Discovery (C2D3)
• Cambridge Neuroscience Seminars
• Cambridge University Engineering Department, CBL, BE4-38 (http://learning.eng.cam.ac.uk/Public/Directions)
• Cambridge talks
• Chris Davis' list
• Computational Neuroscience
• Computational and Biological Learning Seminar Series
• Featured lists
• Guy Emerson's list
• Hanchen DaDaDash
• Inference Group Journal Clubs
• Inference Group Summary
• Information Engineering Division seminar list
• Interested Talks
• Life Science
• Life Science Interface Seminars
• Life Sciences
• Life Sciences
• ME Seminar
• Neuroscience
• Neuroscience Seminars
• Neuroscience Seminars
• Quantum Matter Journal Club
• Required lists for MLG
• Stem Cells & Regenerative Medicine
• TQS Journal Clubs
• Trust & Technology Initiative - interesting events
• bld31
• custom
• dh539
• my_list
• ndk22's list
• ob366-ai4er
• other talks
• rp587
• se456's list
• yk373's list

Note that ex-directory lists are not shown.