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Modelling C. elegans pharynx

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The pharynx of the nematode Caenorhabditis elegans is a neuromuscular organ that exhibits typical pumping motions, which result in the intake of food particles from the environment. In our study, the C. elegans pharynx was modeled in a bottom–up fashion, including all of the underlying biological processes that lead to its end function, food intake. Mathematical modeling of all processes allowed performing comprehensive, quantitative analyses of the system as a whole. Our study exemplifies the power of mathematical models, which allow a more accurate, higher-resolution inspection of the studied system, and an easier and faster execution of in silico experiments than feasible in the lab.

This talk is part of the Computational Neuroscience series.

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