What has genomics ever done for us? A 20-year history of the human genome

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• Klaudia Walter, Sanger Institute
• Thursday 21 March 2024, 19:15-21:30
• Lightfoot Room, Divinity School, St John's College, Cambridge, CB2 1TP.

If you have a question about this talk, please contact Peter Watson.

The Human Genome Project (HGP) was launched in 1990 as the world’s largest collaborative biological project to determine the three billion base pairs that make up human DNA . It was completed in 2003 with 92% of the genome completed, and at a cost of $2.7 billion. Since then, thousands of genomes have been sequenced at much greater speed and at much reduced cost of $600 (or less); the total amount of data runs in the order of petabytes (millions of gigabytes).

The UK10K Cohorts Project was an early project (2010-2015) based on whole-genome sequence data from almost 4,000 individuals to research the relationship between rare and common genetic variants with a comprehensive set of quantitative measures that are relevant to cardiovascular and metabolic disease. The largest whole-genome sequence project to date is UK BioBank (https://www.ukbiobank.ac.uk/) with whole-genome sequence data for 500,000 individuals that can be linked to a wide range of biochemistry markers, online questionnaires, electronic health-related records and MR imaging data.

This talk is part of the Cambridge Statistics Discussion Group (CSDG) series.

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