Florian Markowetz

Name:	Florian Markowetz
Affiliation:	University of Cambridge
E-mail:	(only provided to users who are logged into talks.cam)
Last login:	Tue Jan 24 12:51:53 +0000 2023

Public lists managed by Florian Markowetz

• Seminars on Quantitative Biology @ CRUK Cambridge Institute

Talks given by Florian Markowetz

Obviously this only lists talks that are listed through talks.cam. Furthermore, this facility only works if the speaker's e-mail was specified in a talk. Most talks have not done this.

• DERIVING CHEMOSENSITIVITY FROM CELL LINES: FORENSIC BIOINFORMATICS AND REPRODUCIBLE RESEARCH IN HIGH-THROUGHPUT BIOLOGY
• Presenting paper: "Oncogenic pathway signatures in human cancers as a guide to targeted therapies"

Talks organised by Florian Markowetz

This list is based on what was entered into the 'organiser' field in a talk. It may not mean that Florian Markowetz actually organised the talk, they may have been responsible only for entering the talk into the talks.cam system.

• Engineering model-based systems to monitor and steer subclonal dynamics
• Decision making in hierarchical multi-label classification (HMC) problems
• Sex chromosomes in development and disease
• Gene-drug interaction screens in cancer
• Adventures in structural variation and evolution in cancer
• Title to be confirmed
• Mining the root causes, driver mutations snd therapeutic opportunities from recalcitrant cancers
• Title to be confirmed
• Title to be confirmed
• Discovering enhancer sequences with a role in vertebrate left-right patterning
• A Horizontal Transfer from Bacteria to Fungi Enhances Fungal Pathogenicity
• Title to be confirmed
• Reconstructing the evolutionary history of tumours
• Whole-genome sequencing of cell-free DNA in maternal plasma
• Targeting the brain tumour stem cell phenotype with small molecules
• Dissecting translation efficiency through lab evolution, genome engineering and inspection of the cancerous genome
• Modelling the transcriptional response to ER signalling in breast cancer cells
• Discovery and allele frequency estimation of somatic twilight zone insertions and deletions
• Therapeutic landscape of cancer drivers
• The Cancer Genome Atlas: oncogenic signature classes and the design of combinatorial therapy
• Variations in genetic and phenotypic diversity during breast cancer progression.
• Single molecule approaches for studying gene expression in intact mammalian tissues.
• Title to be confirmed
• The Resistant Cancer Cell Line (RCCL) collection – cancer cell lines with acquired drug resistance as a pre-clinical and basic science model
• Using time-resolved genetic data to study the evolution of drug resistance.
• Profiling the Subclonal Copy Number Architecture from Whole Genome Sequencing of Heterogeneous Tumours
• Systems biology of stem cell fate
• Incorporating Prior Biological Knowledge into Genetic Association Studies
• Title to be confirmed
• Measuring within-tumour diversity as a universal biomarker for cancer prognosis
• Analysis of a large cancer gene screen in myelodysplastic syndromes
• Colon CSCs are sensitized by HDACinhibitors in a FOXO-dependent fashion
• Platinum Genomes
• Global microRNA level regulation of EGFR-driven cell-cycle protein network in breast cancer
• Petri nets as semi-quantitative modeling method to explore systems behavior of disease-related pathways
• Genome-wide association studies: Lessons from studying a large clinical cohort
• Mapping tumor heterogeneity and developmental trajectories using 40 markers at single cell resolution:
• Inferring causal mediators from omics data in the context of genetic and environmental variations
• The logic and variation in genomic regulatory networks
• Metabolic regulation of the stress response and the cancer cell's Warburg effect
• Evolution of cellular networks: from interactions to phenotypes
• Circulating tumour DNA as a biomarker of genetics alterations in cancer
• Title to be confirmed
• Network biology of cancer
• From protein networks to disease mechanisms
• OPEN
• Variational Methods in 3+Dimensional Biomedical Imaging
• The life histories of 21 breast cancers
• OPEN
• Biological Image Analysis Made Easy
• The evolution of mammalian tissue transcriptomes
• Modeling stem cell differentiation on multiple scales
• Next-Generation Sequencing to Discover Prognostic Marker for Prostate Cancer: Algorithms and Candidates
• Machine learning applications in genetic regulation and cancer
• ShrinkSeq: a flexible and powerful method for Bayesian analysis of RNAseq data
• Evolution of developmental gene expression programs
• Modelling in systems genetics: computational approaches for discovering disease networks
• OPEN
• Model Based Target Identification from Expression Data
• The Search for Organizing Principles in Cancer Systems Biology
• Increased methylation variation across cancer types
• RNAi libraries for high throughput phenotyping and drug resistance screening in the African trypanosome
• RNAi-based molecular computing for cancer cell detection
• Title to be confirmed
• Inferring mechanisms of gene regulation from patterns of evolutionary divergence
• Chromatin-mediated regulation of gene expression in mouse ES cells
• Adult stem cell fate: a laboratory for statistical physics
• Title to be confirmed
• OPEN
• Perturbation Biology of Cancer Cells
• Phylogenetic Inference of Multidomain Evolution
• OPEN
• Allele specific expression design using short read DNA sequencing and application to the genetics of autoimmune disorders
• OPEN
• Title to be confirmed
• CRUK computational biology day
• Do modules or pathways help predict breast cancer outcome?
• From data to bench to bedside - prognostic markers and therapeutic targets in breast cancer
• Evidence of non-random mutation rates suggests a risk management strategy for bacterial evolution
• Intrinsically Unstructured Proteins: Regulation and Disease
• Theoretical models of the development of the nervous system
• Open
• Using association-based genetics to understand basic biology
• Integrative Network Biology and Cellular Information Processing
• The evolution and regulation of gene expression levels in mammals
• Finding interesting clusters using Bayesian data fusion
• Deconvolving the epigenome
• Transcriptional characterization of glioma stem cells using high-throughput tag sequencing
• Evolutionary Signatures of Strand Specific Mutagenic Processes
• Unexpected complex dynamics of cellular transcriptional response
• Open
• Title to be confirmed
• Uncovering signaling differences between normal and transformed hepatocytes using cell-specific pathway models
• A quantitative view of gene expression levels and epigenetic modifications
• ChIP-Seq in six Drosophila species reveals a highly similar binding landscape for the developmental transcription factor Twist.
• Dynamics of molecular clocks expose the lineage relations of cells
• Deep sequencing reveals differential expression of microRNAs in favorable versus unfavorable neuroblastoma
• A global map of human gene expression
• Open
• Learning the structure of graphical models with latent variables
• Open
• Next generation computing for next generation sequencing
• Analysing the pharmacokinetics and pharmacodynamics of drugs in vivo by upgrading in vitro data based on mathematical modelling
• New Approaches to Biomedical Data Modelling: An Introductory Tutorial
• Cancer Tumour/Normal Pair Analysis with the Illumina Genome Analyzer