An exact, efficient, and flexible representation of statistical models for DNA profiles

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• Therese Graversen (Københavns Universitet (University of Copenhagen))
• Wednesday 09 November 2016, 10:15-11:00
• Seminar Room 1, Newton Institute.

If you have a question about this talk, please contact INI IT.

FOSW03 - Statistical modelling of scientific evidence

Many different models have been proposed for a statistical interpretation of mixed DNA profiles. Regardless of the model, a computational bottleneck lies in the necessity to handle the large set of possible combinations of DNA profiles for the contributors to the DNA sample.

I will explain how models can be specified in a very general setup that makes it simple to compute both the likelihood and many other quantities that are crucial to a thorough statistical analysis. Notably all computations in this setup are exact, whilst still efficient.

I have used this setup to implement the statistical software package DNAmixtures.

Related Links

• http://dnamixtures.r-forge.r-project.org/ – The DNAmixtures software package
• http://dx.doi.org/10.1007/s11222-014-9451-7 – Computational aspects of DNA mixture analysis (Graversen and Lauritzen 2015)  

This talk is part of the Isaac Newton Institute Seminar Series series.

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