Two Dimensional Coherent Infra-Red Spectroscopy for the measurement of vibration-vibration coupling, and its application to the study of protein composition, dynamics, structure and function
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If you have a question about this talk, please contact Dr Kalin Dragnevski.
Optical spectroscopy is going through a revolution akin to that which
occurred in Nuclear Magnetic Resonance in the 1970’s. The ability to
produce tunable femtosecond and picosecond optical pulses in the
infra-red allows the measurement of vibrational coupling in a reliable
and rigorous fashion. This class of spectroscopy has become known as two
dimensional infra-red spectroscopy or 2DIR. Multipulse measurements
combined with quantum mechanical calculations allow reliable
interpretation of such data which in turn allows these methods to be
usefully applied to the study of a wide range of soft condensed matter.
In particular these methods show great promise for the study of proteins
and a number of applications are suggested and illustrated ranging from
proteomic screening through ultrafast dynamics to structural analysis.
This talk is part of the BSS Formal Seminars series.
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