Computational and Systems Biology Seminar Series

Illuminating mechanisms of mammalian morphogenesis

Kate McDole (LMB).

Lecture Theatre, Department of Pathology, Tennis Court Road.

Thursday 21 November 2024, 16:00-17:00

Computational and Systems Biology Seminar Series

Digital Twins of Patients on Non-Invasive Respiratory Support: Mechanistic and Data-Driven Models to Improve Patient Care

Declan Bates (University of Warwick).

Lecture Theatre, Department of Pathology, Tennis Court Road.

Thursday 07 November 2024, 16:00-17:00

Computational and Systems Biology Seminar Series

Cell state switches and local adaptation in cancer: insights from AI and ecology-inspired approaches

Maria Secrier (University College London).

Lecture Theatre, Department of Pathology, Tennis Court Road.

Thursday 24 October 2024, 16:00-17:00

Computational and Systems Biology Seminar Series

Somatic evolution of the adaptive immune system in health and disease

Heather Machado (Cambridge Pathology).

Lecture Theatre, Department of Pathology, Tennis Court Road.

Thursday 10 October 2024, 16:00-17:00

Cellular and Molecular Pathology Seminars

Title to be confirmed

Jessica Okosun, Cancer Research UK Barts Centre.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Tuesday 14 March 2023, 12:30-13:30

Cellular and Molecular Pathology Seminars

Title to be confirmed

Dr Sarah Aitken (University of Cambridge).

Lecture Theatre, Department of Pathology, Tennis Court Road.

Tuesday 28 February 2023, 12:30-13:30

Cellular and Molecular Pathology Seminars

Title to be confirmed

Iva Tchasovnikarova (University of Cambridge).

Lecture Theatre, Department of Pathology, Tennis Court Road.

Tuesday 14 February 2023, 12:30-13:30

Cellular and Molecular Pathology Seminars

Title to be confirmed

Hayley Sharpe (University of Cambridge).

Lecture Theatre, Department of Pathology, Tennis Court Road.

Tuesday 31 January 2023, 12:30-13:30

Cellular and Molecular Pathology Seminars

Epigenetic changes arising from acute depletion of the tumour suppressor ARID1A

Tom Owen-Hughes, University of Dundee.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Tuesday 29 November 2022, 12:30-13:30

Cellular and Molecular Pathology Seminars

Inherent mosaicism and extensive mutation of human placentas

Sam Behjati, Wellcome Trust Sanger Institute.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Tuesday 15 November 2022, 12:30-13:30

Cellular and Molecular Pathology Seminars

The ins and outs of cellular quiescence

Alexis Barr, MRC London Institute of Medical Sciences.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Tuesday 01 November 2022, 12:30-13:30

Cellular and Molecular Pathology Seminars

Disentangling strand interactions in DNA damage and repair

Sarah Aitken, MRC Toxicology Unit.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Tuesday 18 October 2022, 12:30-13:30

Immunology in Pathology

Isolation and analysis of Immune niches along the human intestine.

Host: Klaus Okkenhaug (ko256@cam.ac.uk), tea and coffee available at 12.15

Dr. William Winston Agace, Danish Technical University .

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 04 March 2020, 12:30-13:30

Immunology in Pathology

Protection against pathogen colonisation and transmission by the microbiota.

Host: Klaus Okkenhaug (ko256@cam.ac.uk), tea and coffee available at 12.15

Dr. Thomas B. Clarke, Imperial College London.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 26 February 2020, 12:30-13:30

Cellular Genetic Disease Seminar

Clonal dynamics in normal and cancerous testicular tissues.

Host: Paolo D'Avino (ppd21@cam.ac.uk)

Dr Raheleh Rahbari.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Tuesday 25 February 2020, 12:30-13:30

Immunology in Pathology

Oxygen-dependent control of T-cell mediated immunity.

Host: Nick Holmes, (nh106@cam.ac.uk), tea and coffee available at 12.15

Dr. Sarah Ross, Babraham Institute.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 19 February 2020, 12:30-13:30

Immunology in Pathology

Mechanisms of germinal centre dependent antibody dysregulation in early life.

Host: Naomi McGovern, nm390@cam.ac.uk; Tea and coffee will be available at 12.15

Dr James Harker, Imperial College London.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 05 February 2020, 12:30-13:30

Immunology in Pathology

Candida recognition and manipulation of NK cells.

Host: Dr Francesco Colucci (fc287@medschl.cam.ac.uk)

Professor Ofer Mandelboim, Hebrew University of Jerusalem.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Thursday 30 January 2020, 15:00-16:00

Immunology in Pathology

Adaptive control of RIPK1 dependent cell death signalling in T-cells.

Tea and coffee will be available at 12.15

Professor Ben Seddon, University College London.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 29 January 2020, 12:30-13:30

Immunology in Pathology

Molecular approaches for studying antigen processing topology and T-cell activation kinetics.

Host: Louise Boyle (lhb22@cam.ac.uk), tea and coffee available at 12.15pm

Dr. Sander van Kasteren, Leiden University.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 22 January 2020, 12:30-13:30

Immunology in Pathology

Epitope target discovery: what can we see when we think outside the box.

Host: Louise Boyle (lhb22@cam.ac.uk), tea and coffee available at 12.15pm

Dr Michele Mishto, Kings College London.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 15 January 2020, 12:30-13:30

Immunology in Pathology

Integrative NMR, Molecular Modeling, and Functional studies of immune recognition complexes

Host: Louise Boyle (lhb22@cam.ac.uk), tea and coffee available at 12.15pm

Dr Nikolaos Sgourakis, University of California, Santa Cruz.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 11 December 2019, 12:30-13:30

Immunology in Pathology

Meticulous and Multifaceted: How herpes viruses fine tune the innate immune response.

Host: Brian Ferguson (bf234@cam.ac.uk)

Professor Melanie Brinkman, Helmholtz Centre for Infection Research.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 27 November 2019, 12:30-13:30

Immunology in Pathology

Immune cell recognition on a nanoscale.

Host: Louise Boyle (lhb22@cam.ac.uk)

Professor Daniel Davis, University of Manchester.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 20 November 2019, 12:30-13:30

Immunology in Pathology

HLA-E Revisited

Host: John Trowsdale (Jt233@cam.ac.uk)

Professor Andrew McMichael, Oxford University.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 13 November 2019, 12:30-13:30

Immunology in Pathology

Understanding hepatic macrophage heterogeneity and function in NAFLD

Host: Naomi McGovern (nm390@cam.ac.uk)

Professor Charlotte Scott, University of Ghent.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 06 November 2019, 12:30-13:30

Immunology in Pathology

CD8 T cell surveillance of lymphoid and non-lymphoid tissues.

Host: Klaus Okkenhaug (ko256@cam.ac.uk)

Professor Jens Stein, University of Fribourg.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 30 October 2019, 12:30-13:30

Immunology in Pathology

How do macrophages respond to danger?

Host: Naomi McGovern, nm390@cam.ac.uk; Tea and coffee will be available at 12.15

Dr Gloria Lopez-Castejon, University of Manchester.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 23 October 2019, 12:30-13:30

Immunology in Pathology

Integrating T cell Signals

Note unusual time, (Tuesday 1230) (12.15 Refreshments available)

Dr Pamela Schwartzberg MD PhD, Senior Investigator, Laboratory of Immune System Biology, National Institute of Allergy and Infectious Diseases and National Human Genome Research Institute, National Institutes of Health, Maryland, USA.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Tuesday 16 July 2019, 12:30-13:30

Immunology in Pathology

From SNPs to biology in autoimmune disease

Host: James Traherne (jat51@cam.ac.uk)

Dr James Lee, Wellcome Trust Intermediate Clinical Fellow and Consultant Gastroenterologist, University of Cambridge .

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 12 June 2019, 13:00-14:00

Immunology in Pathology

Intracellular trafficking for immunity

Host: Brian Ferguson (bf234@cam.ac.uk)

Dr Justine Mintern, Head of Vaccine Biology Laboratory & ARC Future Fellow, University of Melbourne, Australia.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 05 June 2019, 13:00-14:00

Immunology in Pathology

Uterine immunity one cell at a time

Host: Dr Bidesh Mahata (bm11@sanger.ac.uk)

Dr Roser Vento-Tormo, Wellcome Sanger Institute.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 29 May 2019, 13:00-14:00

Immunology in Pathology

‘In vivo tracking of immune cell migration: towards a better understanding of tumour infiltrating lymphocytes’

Host: Dr Bidesh Mahata (bm11@sanger.ac.uk)

Dr David Withers, Institute of Immunology and Immunotherapy, Birmingham.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 22 May 2019, 13:00-14:00

Immunology in Pathology

Adaptive immunity in wild songbirds

Host: Professor Jim Kaufman (jfk31@cam.ac.uk)

Professor Helena Westerdahl, Lund University,Sweden.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 15 May 2019, 13:00-14:00

Cellular Genetic Disease Seminar

How ageing affects melanoma biology and outcome

Host: Dr Paolo D'Avino (ppd21@cam.ac.uk)

Dr Amaya Viros.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Tuesday 14 May 2019, 12:30-13:30

Immunology in Pathology

Antigen receptor repertoires and specificities at single-cell resolution

Host: Dr Bidesh Mahata (bm11@sanger.ac.uk)

Dr Mike Stubbington, 10X Genomics.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 08 May 2019, 13:00-14:00

Immunology in Pathology

Regulators of chicken B cell development – basic research and application

Host: Professor Jim Kaufman (jfk31@cam.ac.uk)

Dr. Sonja Härtle, Ludwig Maximillian University, Munich.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 01 May 2019, 13:00-14:00

Immunology in Pathology

Fish 'n' HIFs: Hypoxia signalling in zebrafish models of infection and inflammation

Host: Dr Naomi McGovern (nm390@cam.ac.uk)

Dr Philip Elks, University of Birmingham .

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 24 April 2019, 13:00-14:00

Immunology in Pathology

Immune regulatory functions of group 2 innate lymphoid cells

Host: Professor Klaus Okkenhaug (ko256@cam.ac.uk)

Dr Tim Halim, CRUK.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 13 March 2019, 13:00-14:00

Immunology in Pathology

Niche dependencies for normal and malignant B1 cells

Host: Professor Klaus Okkenhaug (ko256@cam.ac.uk)

Dr Ingo Ringshausen, Department of Haematology.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 06 March 2019, 12:30-13:30

Cellular Genetic Disease Seminar

Elimination of cervical cancer by 2050: Reality or wishful thinking

Host: Dr Paolo D'Avino (ppd21@cam.ac.uk)

Professor Margaret Stanley, Dept of Pathology, Cambridge.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Tuesday 05 March 2019, 12:30-13:30

Immunology in Pathology

Organoid Systems to Study the Maternal-Fetal Interface of Human Pregnancy

Host: Dr Naomi McGovern (nm390@cam.ac.uk)

Dr Margherita Turco, Department of Pathology, Cambridge.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 27 February 2019, 12:30-13:30

Immunology in Pathology

Beyond the cancer cell: Exploring the tumour stroma as immune modulators

Host: Professor Klaus Okkenhaug (ko256@cam.ac.uk)

Dr Jacqueline Shields, MRC Cancer Unit.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 20 February 2019, 12:30-13:30

Immunology in Pathology

Engineering the genetic events of lymphomagenesis in normal human germinal centre B-cells

Host: Professor Klaus Okkenhaug (ko256@cam.ac.uk)

Dr Daniel Hodson, Department of Haematology.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 13 February 2019, 12:30-13:30

Cellular Genetic Disease Seminar

The p53 family in the cancer cell response to hypoxia

Host: Dr Paolo D'Avino (ppd21@cam.ac.uk)

Dr Ivano Amelio, MRC Toxicology Unit, Cambridge.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Tuesday 12 February 2019, 12:30-13:30

Cellular Genetic Disease Seminar

Constitutive heterochromatin regulation of genome organisation and stability in mouse embryonic stem cells

Host: Dr Paolo D'Avino (ppd21@cam.ac.uk)

Dr Clara Novo, Babraham Institute.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Tuesday 05 February 2019, 12:30-13:30

Immunology in Pathology

CANCELLED

Canceled

Dr Andrea Ablasser, Ecole Polytechnique Fédérale de Lausanne.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 30 January 2019, 12:30-13:30

Immunology in Pathology

Darwin's digital moth: predicting the existence of new components of immune systems by evaluating convergent patterns of nucleotide motif usage in viruses and their hosts

Host: Dr Brian Ferguson (bf234@cam.ac.uk)

Dr Francisco Lobo, Belo Horizonte.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Friday 25 January 2019, 12:30-13:30

Immunology in Pathology

Mitochondria as inflammatory killers

Host: Dr Brian Ferguson (bf234@cam.ac.uk)

Professor Stephen Tait, University of Glasgow.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 28 November 2018, 12:30-13:30

Cellular Genetic Disease Seminar

How to start a procentriole

Host: Dr Paolo D'Avino (ppd21@cam.ac.uk)

Professor Andrew Goryachev, University of Edinburgh.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Tuesday 27 November 2018, 13:00-14:00

Immunology in Pathology

T cell intrinsic role of Arginase 2 in modulating anti-tumor immunity

Host: Professor Jim Kaufman (jfk31@cam.ac.uk)

Professor Walter Reith, University of Geneva .

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 21 November 2018, 12:30-13:30

Immunology in Pathology

Host MHC and genomic diversity retards experimental evolution of viral virulence

Host: Professor Jim Kaufman (jfk31@cam.ac.uk)

Professor Wayne Potts, University of Utah.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 07 November 2018, 12:30-13:30

Immunology in Pathology

Understanding human innate immune memory

Host: Dr Naomi McGovern (nm390@cam.ac.uk)

Dr Andreas Schlitzer,University of Bonn.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 24 October 2018, 12:30-13:30

Immunology in Pathology

Monocyte kinetics and functions in health and disease

Host: Dr Naomi McGovern (nm390@cam.ac.uk)

Dr Simon Yona, University College London.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 17 October 2018, 12:30-13:30

Immunology in Pathology

New insights into how Butyrophilin(-like) proteins shape gammadelta T cell repertoires

Host: Professor Jim Kaufman (jfk31@cam.ac.uk)

Dr Pierre Vantourout, Kings College London.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 10 October 2018, 12:30-13:30

Immunology in Pathology

Tracking hematopoietic clonal life histories in the rhesus macaque model

Host: Dr Andrew Sharkey (as168@cam.ac.uk)

Professor Cindy Dunbar, NIH / NHLBI.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 12 September 2018, 09:30-10:30

Immunology in Pathology

Global outbreaks: interferons as first responders

Host: Professor Klaus Okkenhaug (ko256@cam.ac.uk)

Professor Eleanor N Fish, University of Toronto.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Tuesday 26 June 2018, 13:00-14:00

Immunology in Pathology

Challenges in human respiratory viral infection

Host: Professor Klaus Okkenhaug (ko256@cam.ac.uk)

Dr Christopher Chiu, Imperial College London.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 06 June 2018, 12:30-13:30

Immunology in Pathology

Adaptive immunesurveillance by human γδ T cells

Host: Dr David Rhodes (dar32@cam.ac.uk)

Dr Martin Davey, University of Birmingham.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 30 May 2018, 12:30-13:30

Immunology in Pathology

Regulation of resistance and tolerance at the intestinal barrier

Host: Professor Klaus Okkenhaug (ko256@cam.ac.uk)

Dr Virginia Pedicord, Sanger Institute.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 23 May 2018, 12:30-13:30

Immunology in Pathology

Red Queen drives selection on MHC genes

Host: Professor Jim Kaufman(jfk31@cam.ac.uk)

Professor Jacek Radwan, Adam Mickiewicz University, Poznan.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 16 May 2018, 12:30-13:30

Cellular Genetic Disease Seminar

Single cell transcriptomes from human kidneys reveal the cellular identity of renal tumours

Host: Dr Matthew Murray (mjm16@cam.ac.uk)

Dr Sam Behjati, Wellcome Sanger Institute.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Tuesday 08 May 2018, 12:30-13:30

Immunology in Pathology

A novel aspect of Macrophage biology: learning from the great opportunist HIV-1

Host: Dr Naomi McGovern (nm390@cam.ac.uk)

Dr Petra Mlcochova, University College London.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 02 May 2018, 12:30-13:30

Immunology in Pathology

Novel kinases controlling T cell development, trafficking and immune responses

Host: Professor Klaus Okkenhaug (ko256@cam.ac.uk)

Dr Robert Koechl, King's College London.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 25 April 2018, 12:30-13:30

Immunology in Pathology

Type I IFN induces CXCL13-driven B cell recruitment to the lung to enable tertiary GC formation

Host: Dr Brian Ferguson (bf234@cam.ac.uk)

Dr Michelle Linterman, Babraham Institute, Cambridge.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 14 March 2018, 12:30-13:30

Immunology in Pathology

Characterizing Immunogenetic Mechanisms through HIV Disease Analysis

Host: Dr James Traherne (jat51@cam.ac.uk)

Dr Mary Carrington, NIH, NCI.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Monday 12 March 2018, 12:30-13:30

Immunology in Pathology

Metabolic regulation of T cell trafficking

Host: Professor Klaus Okkenhaug (ko256@cam.ac.uk)

Professor Federica Marelli-Berg, Queen Mary University London.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 07 March 2018, 12:30-13:30

Immunology in Pathology

NK cells: in and out of the circulation

Host: Dr Andrew Sharkey (as168@cam.ac.uk)

Dr Viki Male, University College London.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 28 February 2018, 12:30-13:30

Immunology in Pathology

'Gene regulation in the innate and adaptive immune systems'

Host: Dr Nick Holmes (nh106@cam.ac.uk)

Dr Rahul Roychoudhuri, Babraham Institute, Cambridge.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 21 February 2018, 12:30-13:30

Immunology in Pathology

A sex-linked supergene controls sperm morphology and swimming speed in a songbird

Host: Professor Jim Kaufman (jfk31@cam.ac.uk)

Professor Jon Slate, University of Sheffield.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 14 February 2018, 12:30-13:30

Immunology in Pathology

How T-cells cause autoimmune disease and hold the key to curing cancer

Host: Professor Jim Kaufman (jfk31@cam.ac.uk)

Professor Andrew Sewell, Cardiff University.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 07 February 2018, 12:30-13:30

Immunology in Pathology

Phenotypic model explains adaptation of T cell responses to antigen by TCR downregulation

Host: Dr Nick Holmes (nh106@cam.ac.uk)

Dr Omer Dushek, University of Oxford.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 31 January 2018, 12:30-13:30

Immunology in Pathology

Diversity of the human response to malaria

Host: Dr Maja Wållberg (mw394@cam.ac.uk)

Dr Phil Spence, University of Edinburgh.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 17 January 2018, 12:30-13:30

Immunology in Pathology

Metabolic adaptation as a disease tolerance mechanism against infection

Host: Dr Brian Ferguson (bf234@cam.ac.uk)

Dr Miguel Soares, IGC Lisbon.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 29 November 2017, 12:30-13:30

Immunology in Pathology

Immunity in early life: the case of gammadelta T cells

Host: Dr David Rhodes (dar32@cam.ac.uk)

Dr David Vermijlen, Universite libre de Bruxelles.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 22 November 2017, 12:30-13:30

Immunology in Pathology

Stromal microenvironments and the control T-cell development and selection

Host: Dr Nick Holmes (nh106@cam.ac.uk)

Professor Graham Anderson, Universitiy of Birmingham.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 15 November 2017, 12:30-13:30

Immunology in Pathology

Glucose inhibits Dendritic cell-induced CD8 T cell responses

Host: Dr Maja Wallberg (mw394@cam.ac.uk)

Dr David Finlay, Trinity College, Dublin.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 08 November 2017, 12:30-13:30

Immunology in Pathology

Genetic analyses of ANCA-associated vasculitis inform diagnostic and therapeutic strategies.

Host: Dr James Traherne (jat51@cam.ac.uk)

Dr Paul Lyons, CIMR.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 01 November 2017, 12:30-13:30

Immunology in Pathology

Dendritic cells and antigen export into the cytosol for cross-presentation

Host: Dr Louise Boyle (lhb22@cam.ac.uk

Dr Patrycja Kozik, MRC LMB, Cambridge.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 25 October 2017, 12:30-13:30

Immunology in Pathology

Exploring the functions of monocyte subsets

Host: Dr Naomi McGovern (nm390@cam.ac.uk)

Dr Kevin Woollard, Imperial College London.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 18 October 2017, 12:30-13:30

Immunology in Pathology

Death receptors and ubiquitin in cell death, inflammation and immunity

Host: Dr Brian Ferguson (bf234@cam.ac.uk)

Professor Henning Walczak, University College London.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 04 October 2017, 12:30-13:30

Cellular Genetic Disease Seminar

Genomics for precision oncology: How hard can it be?

Host: Professor Nick Coleman (nc109@cam.ac.uk)

Professor Cristin Print, University of Auckland.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Friday 29 September 2017, 12:00-13:00

Cellular Genetic Disease Seminar

Dissecting the Three-Protein Brain of a Bacterium: E. coli's Chemosensory Array

Host: Dr Paolo D'Avino (ppd21@cam.ac.uk) & Dr Gillian Fraser (gmf25@cam.ac.uk)

Professor John Sandy Parkinson, University of Utah, USA.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 13 September 2017, 12:00-13:00

Immunology in Pathology

Dr David Tscharke: Vaccinia virus presents: A proteome-wide view of antigen presentation during virus infection

Host: Dr Brian Ferguson (bf234@cam.ac.uk)

Dr David Tscharke, Australian National University, Canberra .

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 26 July 2017, 12:30-13:30

Pathology Valedictory Seminars

Julia Muenzener: Viral subversion of host cell membrane trafficking

Julia Muenzner, Department of Pathology.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Monday 17 July 2017, 13:00-14:00

Cellular Genetic Disease Seminar

Using Drosophila melanogaster for dissecting the role of Golgi trafficking in cytokinesis and human diseases

Host: Dr Paolo D'Avino (ppd21@cam.ac.uk)

Dr. Maria Grazia Giansanti, Istituto di Biologia e Patologia molecolari, Rome.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 12 July 2017, 13:00-14:00

Pathology Valedictory Seminars

Rintaro Hiraide: Characterisation of species specific aspect of the porcine interferon response

Rintaro Hiraide, Department of Pathology.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Tuesday 11 July 2017, 14:00-15:00

Pathology Valedictory Seminars

Bo Shiun Lai: Fine-tuning the host immune response by Toxoplasma gondii through ROP13

Bo Shiun Lai, Department of Pathology.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Thursday 29 June 2017, 14:00-15:00

Pathology Valedictory Seminars

Paul Bergen: Ordered export of proteins to build a bacterial cell surface nanomachine

Paul M Bergen, Department of Pathology.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 14 June 2017, 16:00-17:00

Pathology Microbiology Seminar Series

Bacterial warfare: the Type VI secretion system of Serratia marcescens

Dr Sarah Coulthurst, School of Life Sciences, University of Dundee.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Thursday 08 June 2017, 11:00-12:00

Immunology in Pathology

Dr Maike de la Roche: Hedgehog Signalling in T cells

Host: Dr Louise Boyle (lhb22@cam.ac.uk)

Dr Maike de la Roche, Cancer Research UK, Cambridge Institute.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 07 June 2017, 12:30-13:30

Immunology in Pathology

Dr Becca Asquith: KIRs, CD8 T cell dynamics and control of chronic viral infection

Dr Becca Asquith, Imperial College London.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 31 May 2017, 12:30-13:30

Immunology in Pathology

Dr Sarah Teichmann: Understanding Cellular Heterogeneity

Host: Dr Nick Holmes (nh106@cam.ac.uk)

Dr Sarah Teichmann, Sanger Institute.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 24 May 2017, 12:30-13:30

Immunology in Pathology

Dr Tony Jackson: Protein neighbours and proximity proteomics

Host: Prof Jim Kaufman (jfk31@cam.ac.uk)

Dr Tony Jackson, Department of Biochemistry, Cambridge.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 17 May 2017, 12:30-13:30

Immunology in Pathology

Professor Alain Vanderplasschen: Conserved fever pathways across vertebrates: a herpesvirus delays fish behavioural fever through expression of a decoy Tnfα receptor

Host: Prof Jim Kaufman (jfk31@cam.ac.uk)

Professor Alain Vanderplasschen, University of Liege.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 10 May 2017, 12:30-13:30

Immunology in Pathology

Dr David Komander: Studying non-existent ubiquitin chains

Host: Dr Brian Ferguson (bf234@cam.ac.uk)

Dr David Komander, MRC Laboratory of Molecular Biology, Cambridge.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 03 May 2017, 12:30-13:30

Immunology in Pathology

Prof Jan Rehwinkel: Nucleic Acid Sensing by Innate Immune Receptors

Host: Dr Brian Ferguson (bf234@cam.ac.uk)

Professor Jan Rehwinkel, University of Oxford.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 26 April 2017, 12:30-13:30

Immunology in Pathology

Dr Amir Horowitz: Harnessing NK cell functions for treatments against viruses and cancers

Host: Dr Andrew Starkey

Dr Amir Horowitz, Aaron Diamond AIDS Research Center, Rockefeller University, New York.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 15 March 2017, 12:30-13:30

Immunology in Pathology

Prof Serge Muyldermans: Nanobodies, a versatile tool for multiple applications

Host: Lisa Kent (lsk29@cam.ac.uk)

Professor Serge Muyldermans, Vrije Universiteit, Brussel.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 08 March 2017, 12:30-13:30

Immunology in Pathology

Prof Benedikt Kaufer: Herpesvirus latency: From neuronal models to integration into host telomeres

Host: Prof Jim Kaufman (jfk31@cam.ac.uk)

Professor Benedikt Kaufer, Institute of Virology, Freie Universitat, Berlin.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 01 March 2017, 12:30-13:30

Immunology in Pathology

Dr Serge Mostowy: New roles for the cytoskeleton in cell-autonomous immunity

Host: Dr Francesco Colucci (fc287@medschl.cam.ac.uk)

Dr Serge Mostowy, Imperial College, London.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 22 February 2017, 12:30-13:30

Immunology in Pathology

Prof Steve Renshaw: Will zebrafish help lead a revolution in inflammation biology?

Host: Dr Milka Sarris (ms543@cam.ac.uk)

Professor Steve Renshaw, University of Sheffield.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 15 February 2017, 12:30-13:30

Immunology in Pathology

Prof Peter Parham: Resurrecting an Intermediate in the Evolution of Human HLA-C specific NK Cell Receptors

Host: Prof Jim Kaufman (jfk31@cam.ac.uk)

Professor Peter Parham, Stanford University.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Tuesday 14 February 2017, 12:30-13:30

Immunology in Pathology

Dr Neil McCarthy: Human Vδ2+ T-cells in Intestinal Inflammation

Host: Dr David Rhodes (dar32@cam.ac.uk)

Dr Neil McCarthy, The Blizard Institute, The London School of Medicine and Dentistry.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 08 February 2017, 12:30-13:30

Immunology in Pathology

Dr Leonie Unterholzner: Sensing intracellular DNA as "stranger" and "danger" signal

Host: Ben Trigg (bjt40@cam.ac.uk)

Dr Leonie Unterholzner, University of Lancaster.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 01 February 2017, 12:30-13:30

Immunology in Pathology

Dr Frank Waldron-Lynch: Immune Cell Responses in Participants with Type 1 Diabetes after doses of Interleukin-2 in adaptive-response clinical trials

Host: Dr Louise Boyle (lhb22@cam.ac.uk)

Dr Frank Waldron-Lynch, Division of Experimental Medicine & Immunotherapeutics, School of Clinical Medicine, University of Cambridge.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 25 January 2017, 12:30-13:30

Immunology in Pathology

Prof Anthony Purcell: New insights into antigen presentation using quantitative immunopeptidomics

Host: Dr Louise Boyle (lhb22@cam.ac.uk)

Professor Anthony Purcell, Monash University, Melbourne, Australia.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Tuesday 13 December 2016, 12:30-13:30

Immunology in Pathology

Dr Oliver Bannard: Germinal centres; regulation by position and program

Host: Dr Nick Holmes (nh106@cam.ac.uk)

Dr Oliver Bannard, University of Oxford.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 30 November 2016, 12:30-13:30

Immunology in Pathology

Dr Peter van Endert: Intracellular trafficking events regulating MHC class I antigen cross-presentation by dendritic cells

Host: Dr Louise Boyle (lhb22@cam.ac.uk)

Dr Peter van Endert, INSERM, Paris.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 23 November 2016, 12:30-13:30

Immunology in Pathology

Dr David Bending: A novel tool to visualize and manipulate the dynamics of T cell regulation in vivo

Host: Dr Nick Holmes (nh106@cam.ac.uk)

Dr David Bending, Imperial College, London.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 16 November 2016, 12:30-13:30

Immunology in Pathology

Dr Megan MacLeod: Regulation of CD4 T cell retention and function at inflamed sites

Host: Dr Maja Wallberg (mw394@cam.ac.uk)

Dr Megan MacLeod, University of Glasgow.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 02 November 2016, 12:30-13:30

Immunology in Pathology

Professor Geoffrey L Smith: Modulation of CD8+ T cell and NK cell memory by vaccinia virus

Host: Dr Nick Holmes (nh106@cam.ac.uk)

Professor Geoffrey L Smith, Department of Pathology, University of Cambridge.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 26 October 2016, 12:30-13:30

Immunology in Pathology

Dr Pavel Tolar: The biomechanics of B cell activation

Host: Dr Nick Holmes (nh106@cam.ac.uk)

Dr Pavel Tolar, The Francis Crick Institute, London.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 19 October 2016, 12:30-13:30

Immunology in Pathology

Dr Peter Bull: Exploring host selection pressures on malaria parasite populations during human infection

Host: Dr Nick Holmes (nh106@cam.ac.uk)

Dr Peter Bull, Department of Pathology, University of Cambridge.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 12 October 2016, 12:30-13:30

Immunology in Pathology

Dr Anja Schmidt-Christensen: Dissecting inflammation in diabetes

Host: Dr Maja Wallberg (mw394@cam.ac.uk)

Dr Anja Schmidt-Christensen, University of Lund, Sweden.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 05 October 2016, 12:30-13:30

Immunology in Pathology

Dr Peter Bull:

Host: Dr Nick Holmes (nh106@cam.ac.uk)

Dr Peter Bull, Department of Pathology, University of Cambridge.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Monday 12 September 2016, 12:30-13:30

Immunology in Pathology

Dr Duncan Howie: T cell metabolism and immune tolerance

Host: Dr Maja Wallberg (mw394@cam.ac.uk)

Dr Duncan Howie, University of Oxford.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 25 May 2016, 12:30-13:30

Immunology in Pathology

Dr Jodie Goodridge: Natural Killer Potential

Host: Prof John Trowsdale (jt233@cam.ac.uk)

Dr Jodie Goodridge, Oslo University Hospital.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 18 May 2016, 12:30-13:30

Immunology in Pathology

Dr Francois Legoux: CD4+ T cell tolerance to self-antigens

Host: Dr Maja Wallberg (mw394@cam.ac.uk)

Dr Francois Legoux, Institut Curie, Paris.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 11 May 2016, 12:30-13:30

Immunology in Pathology

Prof Paul Bowness: Type 17 immune responses in Ankylosing Spondylitis

Host: Dr Louise Boyle (lhb22@cam.ac.uk)

Professor Paul Bowness, University of Oxford.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 04 May 2016, 12:30-13:30

Immunology in Pathology

Dr Michael Weekes: New insights into human cytomegalovirus immune evasion from quantitative multiplexed proteomics

Host: Dr Louise Boyle (lhb22@cam.ac.uk)

Dr Michael Weekes, Cambridge Institute for Medical Research.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 20 April 2016, 12:30-13:30

Immunology in Pathology

Prof Connie Trimble: HPV therapeutic vaccines – where are we now and where are we going?

Host: Prof Margaret Stanley (mas1001@cam.ac.uk)

Professor Connie Trimble, Johns Hopkins.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 30 March 2016, 12:30-13:30

Immunology in Pathology

Dr Pia Kvistborg: What T cells see on human cancer

Host: Dr Louise Boyle (lhb22@cam.ac.uk)

Dr Pia Kvistborg, Netherlands Cancer Institute, Amsterdam.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 09 March 2016, 12:30-13:30

Immunology in Pathology

Dr Antonio Rothfuchs: Dendritic cell migration and T-cell priming to Bacille Calmette-Guérin

Host: Dr Brian Ferguson (bf234@cam.ac.uk)

Dr Antonio Rothfuchs, Karolinska Institute, Stockholm.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 02 March 2016, 12:30-13:30

Immunology in Pathology

Dr Piero Mastroeni: Immunity and vaccination to invasive Salmonella infections: How can we integrate the lessons from animal models and man?

Host: Prof Jim Kaufman (jfk31@cam.ac.uk)

Dr Piero Mastroeni, Department of Veterinary Medicine, Cambridge.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 24 February 2016, 12:30-13:30

Cellular Genetic Disease Seminar

Dr Nicolae Radu Zabet: Quantitative models of gene regulation: binding of transcription factors to the DNA

Dr Nicolae Radu Zabet, University of Essex.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Tuesday 23 February 2016, 12:30-13:30

Immunology in Pathology

Dr Jane Goodall: How can I modify dendritic cell biology? A lesson from TSLP

Host: Dr Brian Ferguson (bf234@cam.ac.uk)

Dr Jane Goodall, Department of Medicine, Cambridge.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 17 February 2016, 12:30-13:30

Immunology in Pathology

Prof Philip Goulder: Non-progressing paediatric HIV infection

Host: Dr Louise Boyle (lhb22@cam.ac.uk)

Professor Philip Goulder, University of Oxford.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 10 February 2016, 12:30-13:30

Immunology in Pathology

Prof Lutz Walter: Immunogenetics of the rhesus macaque SIV infection model

Host: Prof Jim Kaufman (jfk31@cam.ac.uk)

Professor Lutz Walter, University of Gottingen.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 03 February 2016, 12:30-13:30

Immunology in Pathology

Dr Marion Espeli: New mechanisms of regulation of germinal centre B cells and plasma cells

Host: Dr Maja Wallberg (mw394@cam.ac.uk)

Dr Marion Espeli, INSERM, Paris.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 27 January 2016, 12:30-13:30

Immunology in Pathology

Dr Ian Humphreys: Immune Regulation during Cytomegalovirus Infection: Walking a Fine Line

Host: Dr Louise Boyle (lhb22@cam.ac.uk)

Dr Ian Humphreys, Cardiff University.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 20 January 2016, 12:30-13:30

Immunology in Pathology

Prof Jim Kaufman: A gut feeling about MHC class II molecules

Host: Dr Brian Ferguson (bf234@cam.ac.uk)

Professor Jim Kaufman, Department of Pathology.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 13 January 2016, 12:30-13:30

Immunology in Pathology

Dr Nicola Ternette: Definition of the origin and nature of HLA class I-associated peptide presentation from HIV-1 using mass spectrometry.

Host: Prof Jim Kaufman (jfk31@cam.ac.uk)

Dr Nicola Ternette, NDM, University of Oxford.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 25 November 2015, 12:30-13:30

Cellular Genetic Disease Seminar

Prof Rebecca Fitzgerald: Charting the life history of oesophageal adenocarcinoma and application to earlier diagnosis

Professor Rebecca Fitzgerald, MRC Cancer Unit.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Tuesday 24 November 2015, 12:30-13:30

Immunology in Pathology

Dr Klaus Okkenhaug: PI3K in infection, immunity and cancer.

Host: Dr Brian Ferguson (bf234@cam.ac.uk)

Dr Klaus Okkenhaug, Babraham Institute.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 18 November 2015, 12:30-13:30

Immunology in Pathology

Dr Eoin McKinney: Sometimes better off sick and tired - T cell exhaustion and outcome in autoimmunity and infection.

Host: Dr Louise Boyle (lhb22@cam.ac.uk)

Dr Eoin McKinney, Cambridge Institute for Medical Research.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 11 November 2015, 12:30-13:30

Immunology in Pathology

Dr Emmanuel Donnadieu: Decoding T cell responses to cancer with dynamic imaging

Host: Prof John Trowsdale (jt233@cam.ac.uk)

Dr Emmanuel Donnadieu, Institute Cochin, INSERM, Paris.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 28 October 2015, 12:30-13:30

Cellular Genetic Disease Seminar

Dr Anton Enright: Prediction and analysis of novel long non-coding RNAs in D. melanogaster and Murine spermatogenesis

Dr Anton Enright, EMBL-EBI, Hinxton.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Tuesday 27 October 2015, 12:30-13:30

Immunology in Pathology

Dr Edd James: Immune Dysfunction: the role of polymorphic ERAP1 in disease.

Host: Dr Louise Boyle (lhb22@cam.ac.uk)

Dr Edd James, University of Southampton.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 21 October 2015, 12:30-13:30

Immunology in Pathology

Dr Yongliang Zhang: MKP5, a novel regulator of IRF3-type I IFNs, critically modulates host-pathogen interaction in influenza and other RNA virus infections.

Host: Prof John Trowsdale (jt233@cam.ac.uk)

Dr Yongliang Zhang, National University of Singapore.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 07 October 2015, 12:30-13:30

Immunology in Pathology

Dr Naomi McGovern: Human dendritic cells – from adult to fetus.

Host: Dr Francesco Colucci (fc287@medschl.cam.ac.uk)

Dr Naomi McGovern, SIgN, A*STAR, Singapore.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Monday 05 October 2015, 12:30-13:30

Pathology Valedictory Seminars

Vaccinia virus protein 169 modulates host protein synthesis and affects virulence

Pavla Strnadova

Pavla Strnadova, Department of Pathology.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Thursday 16 July 2015, 13:00-14:00

Immunology in Pathology

Generators of diversity and the host-pathogen interface

Dr Nina Papavasiliou, The Rockefeller Institute, New York

Dr Nina Papavasiliou, The Rockefeller Institute, New York.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 15 July 2015, 12:30-13:30

Immunology in Pathology

Trophoblast-microbiota interaction: a new paradigm on immune regulation during pregnancy

Host: Francesco Colucci (fc287@medschl.cam.ac.uk)

Professor Gil Mor, Yale School of Medicine.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 01 July 2015, 12:30-13:30

Cellular Genetic Disease Seminar

Understanding estrogen receptor-mediated gene regulation in breast cancer

Dr Jason Carroll, Cancer Research UK.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Tuesday 30 June 2015, 12:30-13:30

Immunology in Pathology

Navigating through tissue mazes: how leukocytes find their way to sites of infection’

Host: Brian Ferguson (bf234@cam.ac.uk)

Dr Milka Sarris, Dept of PDN, University of Cambridge.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 10 June 2015, 12:30-13:30

Immunology in Pathology

MHC class I : From viral evasion to cellular quality control?

Host: John Trowsdale (jt233@cam.ac.uk)

Dr Lidia Duncan, CIMR, University of Cambridge.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 03 June 2015, 12:30-13:30

Cellular Genetic Disease Seminar

'Mutant stem cell behaviour in squamous carcinogenesis'

Dr Phil Jones, MRC Cancer Unit.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Tuesday 02 June 2015, 12:30-13:30

Immunology in Pathology

A novel gene essential for the generation of reactive oxygen species and host defence

Host: Nick Holmes (nh106@cam.ac.uk)

Dr David Thomas, Dept of Medicine, University of Cambridge.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 27 May 2015, 12:30-13:30

Immunology in Pathology

Decoding immune responses to cancer and infection using intravital imaging

Host: Milka Sarris (ms543@cam.ac.uk)

Dr Philippe Bousso, Institut Pasteur, Paris.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 20 May 2015, 12:30-13:30

Immunology in Pathology

Tuberculous Granuloma Formation and Function

Host: Brian Ferguson (bf234@cam.ac.uk)

Professor Lalita Ramakrishnan, MRC LMB University of Cambridge.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 13 May 2015, 12:30-13:30

Immunology in Pathology

Studying CD4+ T cell interactions with dendritic cells in vivo

Host: Maja Wallberg (mw394@cam.ac.uk)

Dr Robert Benson, University of Glasgow.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 29 April 2015, 12:30-13:30

Cellular Genetic Disease Seminar

Oncogene-like induction of cellular invasion from centrosome amplification

Dr Susana Godinho, Barts Cancer Institute.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Tuesday 24 March 2015, 12:30-13:30

Immunology in Pathology

New Pathophysiological Roles of Atypical Chemokine Receptors

Host: Dr Milka Sarris (ms543@cam.ac.uk)

Professor Antal Rot, University of York.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 11 March 2015, 12:30-13:30

Immunology in Pathology

Intracellular DNA recognition by the innate immune system

Host: Dr Brian Ferguson (bf234@cam.ac.uk)

Professor Veit Hornung, University of Bonn, Germany.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 04 March 2015, 12:30-13:30

Immunology in Pathology

How protein plasticity influences MHC class I peptide selection: insights into mechanism

Host: Professor Jim Kaufman (jfk31@cam.ac.uk)

Dr Andy van Hateren and Dr Alistair Bailey, Unversity of Southampton.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 25 February 2015, 12:30-13:30

Immunology in Pathology

Group 2 Innate Lymphoid Cells regulate the innate and adaptive immune response to inhaled allergens

Host: Dr Brian Ferguson (bf234@cam.ac.uk)

Dr Tim Halim, MRC LMB, University of Cambridge.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 18 February 2015, 12:30-13:30

Immunology in Pathology

Bacterial autophagy and the cytoskeleton in host defence

Host: Dr Milka Sarris (ms543@cam.ac.uk)

Dr Serge Mostowy, Imperial College London.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 04 February 2015, 12:30-13:30

Immunology in Pathology

Human Cytomegalovirus the paradox of immune evasion and control

Host: Professor John Trowsdale (jt233@cam.ac.uk)

Dr Mark Wills, Dept of Medicine, University of Cambridge.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 28 January 2015, 12:30-13:30

Cellular Genetic Disease Seminar

Transcription factors in oncogenesis: from ALCL to prostate cancer.

Dr Lukas Kenner, Ludwig Boltzmann Institute Cancer Research.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Friday 23 January 2015, 13:00-14:00

Immunology in Pathology

Regulation of T cell homeostasis by tyrosine phosphatase PTPN22

Host: Dr Nick Holmes (nh106@cam.ac.uk)

Dr Robert Salmond, University of Edinburgh.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 21 January 2015, 12:30-13:30

Immunology in Pathology

Responses of mesenchymal stromal cells to hypoxia

Host: Jim Kaufman (jfk31@cam.ac.uk)

Professor Rhodri Ceredig, National University of Ireland, Galway.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 03 December 2014, 12:30-13:30

Immunology in Pathology

The impact of metabolism on NK cell immune functions

Host: John Trowsdale (jt233@cam.ac.uk)

Dr Clair Gardiner, Trinity College, Dublin.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 26 November 2014, 12:30-13:30

Immunology in Pathology

Innate immune cell memory

Host: Brian Ferguson (bf234@cam.ac.uk)

Dr Zoltan Fehervari, Nature Immunology, London.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 19 November 2014, 12:30-13:30

Cellular Genetic Disease Seminar

Insights into cancer from rare diseases

Professor Eamonn Maher, Department of Medical Genetics.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Tuesday 18 November 2014, 12:30-13:30

Immunology in Pathology

Autophagy in host-pathogen interactions

Host: John Trowsdale (jt233@cam.ac.uk)

Dr Felix Randow, MRC LMB, Cambridge.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 12 November 2014, 12:30-13:30

Cellular Genetic Disease Seminar

Translational Epigenetic Inheritance and RNAe

Dr Eric Miska, The Gurdon Institute.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Tuesday 11 November 2014, 12:30-13:30

Immunology in Pathology

The IL-6 cytokine family and CD4+ T cell response during acute and chronic viral infections

Host: Chris Rudd (cer51@cam.ac.uk)

Dr James Harker, Imperial College London.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 05 November 2014, 12:30-13:30

Immunology in Pathology

Myeloid lineage switch in pro-B cells generates novel M phi subsets during homeostasis & inflammation

Host: Paola Zaccone (pz206@cam.ac.uk)

Professor Derek Gilroy, University College London.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Thursday 30 October 2014, 12:30-13:30

Immunology in Pathology

CANCELLED

Host: Brian Ferguson (bf234@cam.ac.uk)

Professor Veit Hornung, University of Bonn, Germany.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 22 October 2014, 12:30-13:30

Immunology in Pathology

Positive and Negative Selection in Avian B Cell Development

Host: Jim Kaufman (jfk31@cam.ac.uk)

Professor Mike Ratcliffe, University of Toronto.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 15 October 2014, 12:30-13:30

Immunology in Pathology

An inverse correlation of cell surface expression level and peptide binding repertoire for MHC class I molecules is associated with disease resistance in chickens and humans

Host: Brian Ferguson (bf234@cam.ac.uk)

Professor Jim Kaufman, Department of Pathology, University of Cambridge.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 08 October 2014, 12:30-13:30

Cellular Genetic Disease Seminar

Embryonic Stem Cells: Capture of the Ground State

Professor Austin Smith, Wellcome Trust-MRC Stem Cell Institute.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Tuesday 08 July 2014, 12:30-13:30

Cellular Genetic Disease Seminar

CANCELLED Translational Epigenetic Inheritance and RNAe

CANCELLED

Dr Erik Miska, Gurdon Institute.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Tuesday 24 June 2014, 12:30-13:30

Immunology in Pathology

Regulation of virally-induced lung inflammation by interferons

Host: Brian Ferguson (bf234@cam.ac.uk)

Dr Cecilia Johansson, Imperial College London.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 11 June 2014, 12:30-13:30

Cellular Genetic Disease Seminar

Mechanisms underlying the developmental origins of health and disease

Dr Susan Ozanne, Metabolic Research Laboratories.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Tuesday 10 June 2014, 12:30-13:30

Immunology in Pathology

Sensing and signalling in innate immunity: Role of PYHIN proteins

Host: Brian Ferguson (bf234@cam.ac.uk)

Professor Andrew Bowie, Trinity College Dublin.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 04 June 2014, 12:30-13:30

Immunology in Pathology

C-type lectins in homeostasis and immunity

Host: Paola Zaccone (pz206@cam.ac.uk)

Professor Gordon Brown, University of Aberdeen.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 28 May 2014, 12:30-13:30

Immunology in Pathology

Killer T Cells: staying on target

Host: Ashley Moffett (am485@cam.ac.uk)

Professor Gillian Griffiths, Cambridge Institute for Medical Research.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 21 May 2014, 12:30-13:30

Immunology in Pathology

Using genomics to refine diagnosis and prognosis in ANCA-associated vasculitis

Host: Professor John Trowsdale (jt233@cam.ac.uk)

Dr Paul Lyons, Cambridge Institute for Medical Research.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 14 May 2014, 12:30-13:30

Cellular Genetic Disease Seminar

Regulated export of specific mRNAs from the cell nucleus

Professor Ron Laskey, Department of Zoology.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Tuesday 13 May 2014, 12:30-13:30

Immunology in Pathology

Ex-FoxP3 Regulatory T cells uniquely populate the inflamed site in childhood arthritis

Host: Nick Holmes (nh106@cam.ac.uk)

Dr David Bending, University College London.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 07 May 2014, 12:30-13:30

Immunology in Pathology

Pattern Recognition Receptors and Infection: Following the Speck

Host: Brian Ferguson (bf234@cam.ac.uk)

Professor Clare Bryant, Dept of Veterinary Medicine, University of Cambridge.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 23 April 2014, 12:30-13:30

Immunology in Pathology

Targeting Immune Checkpoints in Cancer: New Mechanistic Insights

Host: Chris Rudd, cer51@cam.ac.uk

Dr Sergio Quezada, University College London.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 05 March 2014, 12:30-13:30

Immunology in Pathology

Inhibition of HIV-1-cofactor interactions triggers innate sensors and interferon secretion

Host: Brian Ferguson, bf234@cam.ac.uk

Dr Jane Rasayiaah, University College London.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 26 February 2014, 12:30-13:30

Immunology in Pathology

Exploring the mechanisms of immunity operating against a protist parasite of the gut

Host: Ben Trigg, bjt40@cam.ac.uk

Dr Adrian Smith, Dept of Zoology, University of Oxford.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 19 February 2014, 12:30-13:30

Immunology in Pathology

Trafficking of MHC class I molecules is influenced by so many things - lessons from a new peptide-independent mutant

Host: Dr Louise Boyle, lhb22@cam.ac.uk

Professor Sebastian Springer, Jacobs University Bremen.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Thursday 13 February 2014, 12:30-13:30

Immunology in Pathology

How hepatitis B virus exploits the immune environment in the liver

Host: Ashley Moffett, am485@cam.ac.uk

Professor Mala Maini, University College London.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 12 February 2014, 12:30-13:30

Immunology in Pathology

The unicity of diversity: cross-allele T-cell responses against viruses and tumors among different HLA-A supertypes and the structural bases

Host: Jim Kaufman, jfk31@cam.ac.uk

Dr Jun Liu, National Institute for Viral Disease Control and Prevention, China.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 05 February 2014, 12:30-13:30

Immunology in Pathology

Immune-mediated sperm selection

Host: Jim Kaufman, jfk31@cam.ac.uk

Dr Tommaso Pizzari, Dept of Zoology, University of Oxford.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 29 January 2014, 12:30-13:30

Immunology in Pathology

Apoptosis, Necrosis, Atherosclerosis and IL-1

Host: John Trowsdale, jt233@cam.ac.uk

Dr Murray Clarke, Dept of Medicine, University of Cambridge.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 22 January 2014, 12:30-13:30

Immunology in Pathology

The double life of killer cells: NK in reproduction and cancer

Host: John Trowsdale, jt233@cam.ac.uk

Dr Francesco Colucci, Clinical School, University of Cambridge.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 15 January 2014, 12:30-13:30

Immunology in Pathology

Host-pathogen interactions in the chicken - from molecules to mapping

Host: Jim Kaufman (jfk31@cam.ac.uk)

Professor Pete Kaiser, The Roslin Institute, University of Edinburgh.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 04 December 2013, 12:30-13:30

Immunology in Pathology

Migration in Development and Immune Function: the Role of alpha4 integrin (CD49d, VLA-4)

Host: Dr Nick Holmes (nh106@cam.ac.uk)

Dr Alexandre Potocnik, National Institute for Medical Research, Mill Hill, London.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 27 November 2013, 12:30-13:30

Immunology in Pathology

New insight into the mechanism controlling peptide selection by MHC class I

Host: John Trowsdale (jt233@cam.ac.uk)

Dr Louise Boyle, Cambridge Institute for Medical Research.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 20 November 2013, 12:30-13:30

Immunology in Pathology

Transancestral Fine mapping of Susceptibility Loci in SLE

Host: John Trowsdale (jt233@cam.ac.uk)

Professor Timothy Vyse, King's College London.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 13 November 2013, 12:30-13:30

Immunology in Pathology

Reproduction, infection and KIR evolution: a modelling approach

Host: Professor Ashley Moffett (am485@cam.ac.uk)

Dr Bridget Penman, University of Oxford.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 06 November 2013, 12:30-13:30

Immunology in Pathology

Shooting the messenger - Unique cytotoxic strategy in recently activated CD8 T cells

Host: Professor Chris Rudd (cer51@cam.ac.uk)

Professor Michael Dustin, New York University.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 30 October 2013, 12:30-13:30

Immunology in Pathology

Studies on pathogen-macrophage interactions: a possible role for a secreted Mycobacterium tuberculosis lectin

Host: Dr Brian Ferguson (bf234@cam.ac.uk)

Dr Andre Bafica, Universidade Federal de Santa Catarina Florianopolis, Brazil.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 23 October 2013, 12:30-13:30

Immunology in Pathology

Influenza Adrift: Rethinking Influenza A Virus Evolution

Host: Dr Adrian Kelly (apk23@cam.ac.uk)

Dr Jon Yewdell, National Institutes of Health, USA.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 16 October 2013, 12:30-13:30

Immunology in Pathology

Viral inhibition of DNA-PK dependent DNA sensing

Host: Professor Jim Kaufman (jfk31@cam.ac.uk)

Dr Brian Ferguson, Department of Pathology, University of Cambridge.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 09 October 2013, 12:30-13:30

Immunology in Pathology

A View to a Kill - Natural killer cell recognition of classical, non classical and virus-encoded MHC-like molecules

Host: Professor Ashley Moffett (am485@cam.ac.uk)

Professor Andrew Geoffrey Brooks, University of Melbourne, Australia.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 02 October 2013, 12:30-13:30

Immunology in Pathology

Conservation of Binding by Leukocyte Receptor Complex family members to Class I Antigen Presenting Molecules: Why does KIR3DL1 bind Mouse H-2Db?

Host: Professor Ashley Moffett (am485@cam.ac.uk)

Dr Deborah Burshtyn, University of Alberta, Canada.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 25 September 2013, 12:30-13:30

Pathology Seminars

Themes in Host-Pathogen Interactions: Insights from Structural Biology

Dr Erec Stebbins, The Rockefeller University, New York.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Thursday 18 July 2013, 11:00-12:15

Immunology in Pathology

Influence of HLA-C expression level on HIV control

Host: Ashley Moffett (am485@cam.ac.uk)

Dr Richard Apps, National Cancer Institute, NIH Fredericks, USA.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 03 July 2013, 12:30-13:30

Immunology in Pathology

Macrophage heterogeneity and renewal during inflammation

Host: John Trowsdale (jt233@cam.ac.uk)

Professor Philip Taylor, University of Cardiff.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 12 June 2013, 12:30-13:30

Immunology in Pathology

Mothers' compromise. How NK cells regulate placentation.

Host: Jim Kaufman (jfk31@cam.ac.uk)

Dr Andrew Sharkey, Department of Pathology, University of Cambridge.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 05 June 2013, 12:30-13:30

Pathology Seminars

Exploring transcriptional regulatory elements using functional genomics strategies

Dr Ron Chen, Gurdon Institute, University of Cambridge.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Tuesday 04 June 2013, 14:00-15:00

Immunology in Pathology

Immunomodulation of Type 1 Diabetes by Schistosome mansoni products

Host: Jim Kaufman (jfk31@cam.ac.uk)

Dr Paola Zaccone, Dept of Pathology, University of Cambridge.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 29 May 2013, 12:30-13:30

Immunology in Pathology

Recombinant HPA-1a antibody therapy for treatment of fetomaternal alloimmune thrombocytopenia

Host: Mike Clark (mrc7@cam.ac.uk)

Dr Cedric Ghevaert, Dept of Haematology, University of Cambridge.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 22 May 2013, 12:30-13:30

Immunology in Pathology

Burning bridges. Transgenic approaches to eliminate the intermediate hosts of pandemic influenza.

Host: Adrian Kelly (apk23@cam.ac.uk)

Dr Laurence Tiley, Dept of Veterinary Medicine, University of Cambridge.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 15 May 2013, 12:30-13:30

Immunology in Pathology

Foxp3, TSLP, and the regulation of immunity and inflammation

Host: John Rogers, PDN (jhr11@cam.ac.uk)

Dr Steve Ziegler, Benaroya Research Institute, Seattle.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 08 May 2013, 12:30-13:30

Immunology in Pathology

Innate crosstalk of unconventional T cells, monocytes and neutrophils in bacterial infection

Host: John Trowsdale (jt233@cam.ac.uk)

Dr Matthias Eberl, University of Cardiff.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 01 May 2013, 12:30-13:30

Immunology in Pathology

Direct Nuclear Pore Complex Regulation of T-cell Induced Inflammation

Host: Jim Kaufman (jfk31@cam.ac.uk)

Professor Chris Rudd, Dept of Pathology, University of Cambridge.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 24 April 2013, 12:30-13:30

Immunology in Pathology

Immune profiling the human NK cell repertoire using mass cytometry (CyTOF)

Host: Ashley Moffett (am485@cam.ac.uk)

Dr Amir Horowitz, Stanford University.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Tuesday 09 April 2013, 12:30-13:30

Immunology in Pathology

The role of KIR3DL2 HLA-B27 interactions in inflammatory arthritis - symptom or cause?

Host: John Trowsdale (jt233@cam.ac.uk)

Dr Simon Kollnberger, University of Oxford.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 13 March 2013, 12:30-13:30

Immunology in Pathology

Preclinical and clinical studies of immunotherapy in type 1 diabetes

Host: John Trowsdale (jt233@cam.ac.uk)

Dr Frank Waldron-Lynch, CIMR, Cambridge.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 06 March 2013, 12:30-13:30

Immunology in Pathology

Influence of the microbiota on immune system homeostasis

Host: Chris Rudd (cer51@cam.ac.uk)

Professor Dan Littman, New York University, USA.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 27 February 2013, 12:30-13:30

Immunology in Pathology

Recognition of herpesviruses by the innate immune system

Host: Brian Ferguson (bf234@cam.ac.uk)

Professor Søren Riis Paludan, University of Aarhus, Denmark.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 20 February 2013, 12:30-13:30

Immunology in Pathology

'Dendritic cells and pluripotency: Unlikely allies in the pursuit of immunotherapy'

Host: Nick Holmes (nh106@cam.ac.uk)

Dr Paul Fairchild, Dunn School of Pathology, University of Oxford.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 13 February 2013, 12:30-13:30

Immunology in Pathology

The evolution of Natural Killer cell receptors: alternative strategies to recognise self and create immune variation

Host: Hannah Siddle (hvs26@cam.ac.uk)

Dr John Hammond, IAH, Compton.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 06 February 2013, 12:30-13:30

Immunology in Pathology

Defining a role for Natural Killer cells in HCV infection

Host: Ashley Moffett (am485@cam.ac.uk)

Dr Clair Gardiner, Trinity College, Dublin.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 30 January 2013, 12:30-13:30

Immunology in Pathology

IRF5 in regulation of macrophage inflammatory gene programme

Host: Chris Rudd (cer51@cam.ac.uk)

Dr Irina Udalova, Kennedy Institute of Rheumatology, University of Oxford.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 23 January 2013, 12:30-13:30

Immunology in Pathology

Defense, counter defense and counter counter defense in host pathogen interactions of plants

Host: Brian Ferguson (bf234@cam.ac.uk)

Professor Sir David Baulcombe, Dept of Plant Sciences, University of Cambridge.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 16 January 2013, 12:30-13:30

Immunology in Pathology

Lesson from the skin: the Aryl hydrocarbon Receptor (AhR) as an inflammatory brake in psoriasis

Host: Anne Cooke (ac@mole.bio.cam.ac.uk)

Dr Paola Di Meglio, NIMR, Mill Hill, London.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 28 November 2012, 12:30-13:30

Immunology in Pathology

Using super-resolution microscopy to watch immune cells kill

Host: John Trowsdale (jt233@cam.ac.uk)

Professor Dan Davis, Imperial College London.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 21 November 2012, 12:30-13:30

Immunology in Pathology

Hepcidin, immunity and global health

Host: Adrian Kelly (apk23@cam.ac.uk)

Dr Alexander Hal Drakesmith, University of Oxford.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 14 November 2012, 12:30-13:30

Immunology in Pathology

Toll and TLR function in inflammation and neurogenesis

Host: Adrian Kelly (apk23@cam.ac.uk)

Professor Nick Gay, Department of Biochemistry, Cambridge.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 07 November 2012, 12:30-13:30

Immunology in Pathology

Induction of broadly neutralising antibodies against HIV in Llamas

Host: Brian Ferguson (bf234@cam.ac.uk)

Dr Laura McCoy, University College London.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 31 October 2012, 12:30-13:30

Immunology in Pathology

The importance of MHC protein dynamics for antigen presenting function

Host: Jim Kaufman (jfk31@cam.ac.uk)

Professor Tim Elliott, University of Southampton.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 24 October 2012, 12:30-13:30

Immunology in Pathology

LAT signalling pathology: a T-cell dependent, B cell autoimmune condition without T cell self-reactivity

Host: Chris Rudd (cer51@cam.ac.uk)

Professor Bernard Malissen, University of Marseille.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Friday 19 October 2012, 12:30-13:30

Cambridge Immunology Network Seminar Series

“LAT signalling pathology: a T-cell dependent, B cell autoimmune condition without T-cell self-reactivity"

Professor Bernard Malissen, Centre d’Immunologie de Marseille-Luminy. Hosted by Chris Rudd.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Friday 19 October 2012, 12:30-13:30

Immunology in Pathology

Insights into regulatory genetic variation involving the human MHC

Host: John Trowsdale (jt233@cam.ac.uk)

Dr Julian C Knight, University of Oxford.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 17 October 2012, 12:30-13:30

Immunology in Pathology

TLR3-IFN deficiencies underlying Herpes simplex encephalitis

Host: Brian Ferguson (bf234@cam.ac.uk)

Dr Vanessa Sancho-Simizu, Imperial College London.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 10 October 2012, 12:30-13:30

Immunology in Pathology

Novel targets to treat hyper-immune syndromes revealed by physiologic responses to DNA nanoparticles

Host: Anne Cooke (ac@mole.bio.cam.ac.uk)

Professor Andy Mellor, Georgia Health Sciences University, USA.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Monday 08 October 2012, 12:30-13:30

Immunology in Pathology

Selection of IgG properties for therapeutic applications

Host: Jim Kaufman (jfk31@cam.ac.uk)

Dr Mike Clark, Department of Pathology, Cambridge.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 03 October 2012, 12:30-13:30

Cambridge Science Summer School 2012

Pain, and why we need it

Peter McNaughton (Pharmacology, Cambridge).

Lecture Theatre, Department of Pathology, Tennis Court Road.

Friday 10 August 2012, 17:00-18:00

Cambridge Science Summer School 2012

Growth control pathways, epithelial polarity, and cancer

Daniel St Johnston (Gurdon Institute, University of Cambridge).

Lecture Theatre, Department of Pathology, Tennis Court Road.

Friday 13 July 2012, 17:30-18:30

Pathology Seminars

Not quite Houdini: Poxviruses and T cell priming in the face of immune evasion genes

Dr David Tscharke, The Australian National University.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Thursday 05 July 2012, 14:00-15:30

Immunology in Pathology

Nrp-1: Sticky memories?

Host: John Trowsdale (jt233@cam.ac.uk)

Dr Alex Betz, Laboratory of Molecular Biology.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 13 June 2012, 12:30-13:30

Immunology in Pathology

Insights into human papillomavirus persistence and cervical carcinogenesis from the W12 model system

Host: Jim Kaufman (jfk31@cam.ac.uk)

Professor Nick Coleman, Dept of Pathology, Cambridge.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 30 May 2012, 12:30-13:30

Immunology in Pathology

Phylogenetic origin of the vertebrate leukocyte receptors

Host: Jim Kaufman (jfk31@cam.ac.uk)

Prof Dr Louis Du Pasquier, University of Basel.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 23 May 2012, 12:30-13:30

Immunology in Pathology

A quantitative view of gene expression levels in the T helper cell system

Host: Nick Holmes (nh106@cam.ac.uk)

Dr Sarah Teichmann, Laboratory of Molecular Biology.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 16 May 2012, 12:30-13:30

Immunology in Pathology

MHC haplotyping in rhesus and cynomolgus macaques

Host: Jim Kaufman, jfk31@cam.ac.uk

Dr. Gaby Doxiadis, BPRC Rijswijk, The Netherlands.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 09 May 2012, 12:30-13:30

Immunology in Pathology

Elucidating the relative roles of the TCR and CD8 co-receptor in T cell recognition of peptide-MHCI

Host: Jim Kaufman (jfk31@cam.ac.uk)

Dr Linda Wooldridge, University of Cardiff.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 02 May 2012, 12:30-13:30

Immunology in Pathology

Autoreactive CD4 T Cells and their Antigens in Type 1 Diabetes

Host: Anne Cooke (ac@mole.bio.cam.ac.uk)

Professor Katie Haskins, University of Colorado, Denver.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 25 April 2012, 12:30-13:30

Immunology in Pathology

Surprise, surprise! The molecular evolutionary immunoecology of the ubiquitous protozoal pathogen, Toxoplasma gondii

Host: John Trowsdale, jt233@cam.ac.uk

Professor Jonathan Howard, University of Cologne, Germany.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 14 March 2012, 12:30-13:30

Immunology in Pathology

Memory CD4 T cell generation and survival within secondary lymphoid tissue

Host: Jim Kaufman, jfk31@cam.ac.uk

Dr David Withers, University of Birmingham.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 07 March 2012, 12:30-13:30

Immunology in Pathology

The Aryl Hydrocarbon Receptor: an interpreter of the micro-environment

Host: Jim Kaufman, jfk31@cam.ac.uk

Dr Marc Veldhoen, Babraham Institute, Cambridge.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 29 February 2012, 12:30-13:30

Immunology in Pathology

NK cells: turning off the off switch

Host: Ashley Moffett, am485@cam.ac.uk

Professor Salim Khakoo, University of Southampton.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 22 February 2012, 12:30-13:30

Immunology in Pathology

Lessons from pathogens - identifying novel cell surface receptors targeted by viruses

Host: Adrian Kelly, apk23@cam.ac.uk

Professor Paul Lehner, Cambridge Institute for Medical Research.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 15 February 2012, 12:30-13:30

Immunology in Pathology

Natural Killers or Natural Protectors? The Role of NK cells During Intestinal Inflammation

Host: Dr Francesco Colucci, fc287@medschl.cam.ac.uk

Dr Lindsay Hall, University of East Anglia.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 08 February 2012, 12:30-13:30

Immunology in Pathology

Human NK cell activation and inhibition in vivo

Host: John Trowsdale, jt233@cam.ac.uk

Dr Graham Cook, University of Leeds.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 01 February 2012, 12:30-13:30

Immunology in Pathology

The chicken leukocyte receptor cluster

Host: Jim Kaufman, jfk31@cam.ac.uk

Professor Thomas Gobel, Ludwig Maximillian University, Munich.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 25 January 2012, 12:30-13:30

Immunology in Pathology

Are mammary epithelial cells specialised immune cells?

Host: Jim Kaufman, jfk31@cam.ac.uk

Professor Christine Watson, Department of Pathology.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 18 January 2012, 12:30-13:30

Immunology in Pathology

Origin and Transformation of T Cell Progenitors

Host: Jim Kaufman, jfk31@cam.ac.uk

Professor Hans-Reimer Rodewald, German Cancer Research Center, Heidelberg.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 30 November 2011, 12:30-13:30

Lectureship in Innate Immunity

Clonally transmissible cancers in dogs and Tasmanian devils

Dr Elizabeth Murchison, Wellcome Trust Sanger Institute.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Thursday 24 November 2011, 12:00-13:00

Immunology in Pathology

Protective immunity in HIV infection? A tale of two villages

Host: Ashley Moffett, am485@cam.ac.uk

Professor Sarah Rowland-Jones, University of Oxford.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 23 November 2011, 12:30-13:30

Immunology in Pathology

Positive and negative influences of regulatory T cells in generating the naïve T cell compartment

Host: Nick Holmes, nh106@cam.ac.uk

Dr Joanna Davies, Torrey Pines Institute, California.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Thursday 17 November 2011, 12:30-13:30

Immunology in Pathology

A genome-wide consideration of genes controlling MHC class II function and beyond

Host: John Trowsdale, jt233@cam.ac.uk

Professor Jacques Neefjes, Netherlands Cancer Institute.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 16 November 2011, 12:30-13:30

Lectureship in Innate Immunity

Complement dysregulation and innate autoreactivity

Dr Jozsi Mihaly, Leibniz Institute for Natural Product Research.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Monday 14 November 2011, 12:00-13:00

Lectureship in Innate Immunity

Human cytomegalovirus manipulation of host cell immune responses

Dr Emma Poole, University of Cambridge.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Friday 11 November 2011, 12:00-13:00

Immunology in Pathology

Dissecting signals of genetic association to complex diseases within the HLA

Host: John Trowsdale, jt233@cam.ac.uk

Professor Gilean McVean, University of Oxford.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 09 November 2011, 12:30-13:30

Lectureship in Innate Immunity

Novel mechanisms of viral DNA sensing

Dr Brian Ferguson, Imperial College London.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Tuesday 08 November 2011, 12:00-13:00

Immunology in Pathology

Membrane rafts in immunoreceptor signaling - reality vs. artefacts

Host: Helga Schneider, hs383@cam.ac.uk

Professor Vaclav Horejsi, The Institute of Molecular Genetics, Prague.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 02 November 2011, 12:30-13:30

Immunology in Pathology

What have we learnt about the evolution of the cytokine network from studies in fish?

Host: Jim Kaufman, jfk31@cam.ac.uk

Professor Christopher Secombes, University of Aberdeen.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 26 October 2011, 12:30-13:30

Immunology in Pathology

Endosomal Feedback at the T-cell Immune Synapse

Host: Chris Rudd, cer51@cam.ac.uk

Dr Marco Purbhoo, Dept of Medicine, Imperial College London.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 19 October 2011, 12:30-13:30

Immunology in Pathology

Understanding copy number variation in human antimicrobial defensin genes

Host: John Trowsdale, jt233@cam.ac.uk

Professor John Armour, University of Nottingham.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 12 October 2011, 12:30-13:30

Immunology in Pathology

Modulation of innate immunity by vaccinia virus

Host: Jim Kaufman, jfk31@cam.ac.uk

Professor Geoffrey Smith, Department of Pathology.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 05 October 2011, 12:30-13:30

Immunology in Pathology

HIV-1 spread between immune cells

Host: Peter Goon, pg336@cam.ac.uk

Professor Quentin Sattentau, University of Oxford.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 15 June 2011, 12:30-13:30

Immunology in Pathology

Stat3: The Secret Ingredient to turn Lysosomes deadly?

Host: Jim Kaufman, jfk31@cam.ac.uk

Peter Kreuzaler, Dept of Pathology, University of Cambridge.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 08 June 2011, 12:30-13:30

Immunology in Pathology

Mechanisms of immune regulation by CTLA-4: Immunology meets cell biology

Host: John Trowsdale, jt233@cam.ac.uk

Dr David Sansom, University of Birmingham.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 01 June 2011, 12:30-13:30

Immunology in Pathology

Imaging Immune Responses In Vivo

Host: Chris Rudd, cer51@cam.ac.uk

Professor Paul Garside, University of Glasgow.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 18 May 2011, 12:30-13:30

Immunology in Pathology

Macrophage paired receptors - structure, interactions and evolution

Host: Jim Kaufman, jfk31@cam.ac.uk

Professor Neil Barclay, University of Oxford.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 11 May 2011, 12:30-13:30

Immunology in Pathology

How cells defend their cytosol against bacterial invasion

Host: Jim Kaufman, jfk31@cam.ac.uk

Dr Felix Randow, MRC-LMB, Cambridge.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 04 May 2011, 12:30-13:30

Immunology in Pathology

Bacterial interference in MHC class II antigen processing

Host: Jim Kaufman, jfk31@cam.ac.uk

Dr Adrian Kelly, Dept of Pathology, University of Cambridge.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 27 April 2011, 12:30-13:30

Immunology in Pathology

MHC and disease: a novel hypothesis

Host: Jim Kaufman, jfk31@cam.ac.uk

Professor Betsy Mellins, Stanford University, California.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 30 March 2011, 12:30-13:30

Immunology in Pathology

What constitutes a protective HLA class I molecule, and why doesn't it always work?

Host: Peter Goon, pg336@cam.ac.uk

Dr Becca Asquith, Imperial College London.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 16 March 2011, 12:30-13:30

Immunology in Pathology

What are B cells good for?

Host: Jim Kaufman, jfk31@cam.ac.uk

Professor David Gray, University of Edinburgh.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 09 March 2011, 12:30-13:30

Immunology in Pathology

Using our WITS to explore fine structure dynamics of Salmonella and Campylobacter infections

Host: Jim Kaufman, jfk31@cam.ac.uk

Professor Duncan Maskell, Dept of Veterinary Medicine.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 02 March 2011, 12:30-13:30

Immunology in Pathology

Crosstalk between TLR and Stress pathways: relevance to IL-23 expression

Host: John Trowsdale, jt233@cam.ac.uk

Dr Jane Goodall, School of Clinical Medicine.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 23 February 2011, 12:30-13:30

Immunology in Pathology

A selective sweep in chimpanzees: Is SIV the culprit?

Host: Jim Kaufman, jfk31@cam.ac.uk

Dr Ronald Bontrop, Biomedical Primate Research Centre, Rijswijk, The Netherlands.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 09 February 2011, 12:30-13:30

Immunology in Pathology

Probing lymphocyte activation using single chain MHC class I molecules

Host: Peter Goon, pg336@cam.ac.uk

Dr Keith Gould, Imperial College London.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 02 February 2011, 12:30-13:30

Immunology in Pathology

How pathogens reprogram their host: re-wiring of hematopoietic development during acute infection

Host: Anne Cooke, ac@mole.bio.cam.ac.uk

Dr Alexandre Potocnik, National Institute for Medical Research.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 26 January 2011, 12:30-13:30

Immunology in Pathology

BG: a rapidly evolving family of cell surface proteins

Jim Kaufman, jfk31@cam.ac.uk

Professor Jim Kaufman, Department of Pathology, University of Cambridge.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 19 January 2011, 12:30-13:30

Immunology in Pathology

Unraveling the long-term evolutionary history of the bird's MHC class IIB: New data and promising perspectives

Host: Professor Jim Kaufman (jfk31@cam.ac.uk)

Dr Reto Burri.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 15 December 2010, 12:30-13:30

Immunology in Pathology

MHC-dependent sexual and natural selection; insights from ecological studies on birds

Host: Jim Kaufman, jfk31@cam.ac.uk

Dr David Richardson, University of East Anglia.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Monday 13 December 2010, 12:30-13:30

Immunology in Pathology

Specificity and function of NK cells: interplay between HLA class I and KIR gene polymorphism

Host: Ashley Moffett (am485@cam.ac.uk)

Dr Markus Uhrberg, Heinrich Heine University, Dusseldorf.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 01 December 2010, 12:30-13:30

Immunology in Pathology

NK cells: effectors of vaccine-induced immunity?

Professor Eleanor Riley, London School of Hygiene and Tropical Medicine.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 24 November 2010, 12:30-13:30

Immunology in Pathology

The GIMAP/IAN GTPases, regulators of lymphocyte development and survival

Host: John Trowsdale (jt233@cam.ac.uk)

Dr Geoff Butcher, The Babraham Institute.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 17 November 2010, 12:30-13:30

Immunology in Pathology

CD4 T cells during Schistosome infection-limiting liver pathology at the cost of obstructing immunity

Host: Anne Cooke, ac@mole.bio.cam.ac.uk

Dr Mark Wilson, NIMR, London.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 10 November 2010, 12:30-13:30

Immunology in Pathology

Intracellular Immunity: virus neutralisation inside infected cells

Host: John Trowsdale, jt233@cam.ac.uk

Dr Leo James, LMB, Cambridge.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 03 November 2010, 13:30-14:30

Immunology in Pathology

Dispersive Salmonella infections: a hit and run strategy

Host: Adrian Kelly (apk23@cam.ac.uk)

Dr Pietro Mastroeni, Dept of Veterinary Medicine.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 27 October 2010, 12:30-13:30

Immunology in Pathology

Molecular organization and signaling at the T-cell surface: system-level and single molecule-based analysis

Host: Jim Kaufman, jfk31@cam.ac.uk

Professor Simon Davis, University of Oxford.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 20 October 2010, 12:30-13:30

Immunology in Pathology

Marek's disease: an excellent natural model for herpesvirus evolution, vaccines, microRNAs and cancer

Hosts: Jim Kaufman jfk31@cam.ac.uk & Truus Abbink gema2@cam.ac.uk

Professor Venugopal Nair, Institute for Animal Health, Compton.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 13 October 2010, 12:30-13:30

Immunology in Pathology

The immune system in pregnancy

Host: Jim Kaufman jfk31@cam.ac.uk

Professor Ashley Moffett.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 06 October 2010, 12:30-13:30

Immunology in Pathology

The role of drift and selection in shaping worldwide MHC sequence diversity

Host: Jim Kaufman (jfk31@cam.ac.uk)

Dr Francois Balloux, Imperial College, London.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 09 June 2010, 12:30-13:30

Immunology in Pathology

Understanding T cell differentiation through transgenic and semantic analysis of transcriptomes

Host: Nick Holmes (nh106:cam.ac.uk)

Masahiro Ono, King's College, London.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 02 June 2010, 12:30-13:30

Immunology in Pathology

Skin inflammation from genes to function and therapy

Host: Helga Schneider (hs383@cam.ac.uk)

Professor Frank Nestle, King's College, London.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 26 May 2010, 12:30-13:30

Immunology in Pathology

Evolution of quality control strategies in self/non-self discrimination systems

EXTRA TALK; Host: Jim Kaufman (jfk31@cam.ac.uk)

Prof. Dr. Thomas Boehm, University of Freiburg.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 19 May 2010, 15:00-16:00

Immunology in Pathology

Evolution of thymopoiesis in vertebrates

Host: Jim Kaufman (jfk31@cam.ac.uk)

Prof. Dr. Thomas Boehm, University of Freiburg.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 19 May 2010, 12:30-13:30

Immunology in Pathology

Structural defects of the primary and secondary lymphoid organs in the ageing immune system

Host: Adrian Kelly (apk23@cam.ac.uk)

Dr Donald Palmer, Royal Veterinary College, London.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 12 May 2010, 12:30-13:30

Immunology in Pathology

The IFN system in avian influenza infection in chickens

Host: Jim Kaufman (jfk31@cam.ac.uk)

Professor Dr. Bernd Kaspers, University of Munich, Germany.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Tuesday 11 May 2010, 12:30-13:30

Immunology in Pathology

Collagen-binding immune receptors: Form and Function

Host: John Trowsdale (jt233@cam.ac.uk)

Professor Richard Farndale, Dept of Biochemistry, University of Cambridge.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 05 May 2010, 12:30-13:30

Immunology in Pathology

Bridging innate and adaptive immune responses to optimize vaccination strategies

Host: Adrian Kelly (apk23@cam.ac.uk)

Professor Enzo Cerundolo, University of Oxford.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 28 April 2010, 12:30-13:30

Immunology in Pathology

Development of synthetic glycolipid agonists for iNKT cell mediated protection from type 1 diabetes

THIS TALK WILL HAPPEN AS SCHEDULED BUT WITH HOST JIM KAUFMAN (JFK31@CAM.AC.UK) DUE TO ASH CLOUD Host: Anne Cooke (ac@mole.bio.cam.ac.uk)

Professor Terry Delovitch, University of Western Ontario, Canada.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Friday 23 April 2010, 11:30-12:30

Immunology in Pathology

Maintenance of T helper cell memory

Host: Nick Holmes (nh106@cam.ac.uk)

Prof. Dr. Andreas Radbruch, DRFZ, Berlin, Germany.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 24 March 2010, 18:15-19:15

Immunology in Pathology

Controlling secretion at the immunological synapse

Host: Nick Holmes (nh106@cam.ac.uk)

Professor Gillian Griffiths, CIMR, University of Cambridge.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 10 March 2010, 12:30-13:30

Immunology in Pathology

Evolution and involution of CD4 memory

Host: Nick Holmes (nh106@cam.ac.uk)

Professor Peter Lane, University of Birmingham.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 03 March 2010, 12:30-13:30

Immunology in Pathology

The role of natural killer cells in MS

Host: John Trowsdale (jt233@cam.ac.uk); SPONSORED BY Cambridge Research Biochemicals

Professor Danny Altmann, Imperial College, London.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 24 February 2010, 12:30-13:30

Immunology in Pathology

Imaging T cell activation and functional diversification in vivo

Host: Helga Schneider (hs383@cam.ac.uk)

Dr Philippe Bousso, Pasteur Institute, France.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 17 February 2010, 12:30-13:30

Immunology in Pathology

How inhibition leads to activation - the dynamics of natural killer cell education

Host: Francesco Colucci (francesco.colucci@bbsrc.ac.uk)

Professor Petter Höglund, Karolinska Institute, Sweden.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Tuesday 16 February 2010, 12:30-13:30

Immunology in Pathology

The role of NK cells and their receptors in cancer and transplantation

Host: Ashley Moffett (am485@cam.ac.uk)

Professor Jeffrey Miller, University of Minnesota.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Monday 15 February 2010, 12:30-13:30

Immunology in Pathology

Human T cell immunity against tumour antigens

Host: Peter Goon (pg336@cam.ac.uk)

Dr Stephen Man, University of Cardiff.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 10 February 2010, 12:30-13:30

Immunology in Pathology

T cell responses to EBV: viral evasion, antigen immunodominance and priming

Host: Jim Kaufman (jfk31@cam.ac.uk)

Professor Alan Rickinson, University of Birmingham.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 03 February 2010, 12:30-13:30

Immunology in Pathology

New insights into T cell antigen receptor signalling

Host: Chris Rudd (cer51@cam.ac.uk)

Professor Oreste Acuto, Dunn School, University of Oxford.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 27 January 2010, 12:30-13:30

Immunology in Pathology

Immunity and immunopathology in an experimental malaria infection

Host: Anne Cooke (ac@mole.bio.cam.ac.uk)

Dr. Jean Langhorne, National Institute for Medical Research.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 20 January 2010, 12:30-13:30

Immunology in Pathology

Temporal and spatial regulation of cell surface proteinase, MT1-MMP: an essential mechanism for cellular invasion

Host: Helga Schneider (hs383@cam.ac.uk)

Dr. Yoshifumi Itoh, Kennedy Institute, Imperial College London.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 13 January 2010, 12:30-13:30

Immunology in Pathology

HIV microbicides: current and emerging candidates

Host: Chris Rudd (cer51@cam.ac.uk)

Professor Charles Kelly, Oral Immunology, King's College, London.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 02 December 2009, 12:30-13:30

Immunology in Pathology

Adaptive variation and evolutionarily conserved MHC-DRB supertype-binding motifs in Old World primates

Host: Jim Kaufman (jfk31@cam.ac.uk)

Dr Leslie Knapp, Dept of Biological Anthropology, University of Cambridge.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 25 November 2009, 12:30-13:30

Immunology in Pathology

Regulation of airway remodelling in asthma

Host: Andrew Wyllie

Prof. Barry Kay, National Heart and Lung Institute, Imperial College.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 18 November 2009, 12:30-13:30

Immunology in Pathology

Haplotype-specific transcription in the human MHC and susceptibility to autoimmune disease

Host: John Trowsdale (jt233@cam.ac.uk); sponsored by Gen-Probe

Dr Julian Knight, Wellcome Trust Centre for Human Genetics, University of Oxford.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 11 November 2009, 12:30-13:30

Immunology in Pathology

miRNA-155 regulates immune responses

Host: Anne Cooke (ac@mole.bio.cam.ac.uk)

Dr Elena Vigorito, Babraham Institute, Cambridge.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 04 November 2009, 12:30-13:30

Immunology in Pathology

Reverse Phenotyping: towards an integrated (epi)genomic approach to common disease and complex phenotypes

Host: John Trowsdale (jt233@hermes.cam.ac.uk)

Prof. Stephan Beck, University College London.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Monday 26 October 2009, 12:30-13:30

Immunology in Pathology

Additional layers of complexity in the KIR:MHC systems

Host: Ashley Moffet (am485@cam.ac.uk)

Professor Salim Khakoo, Division of Medicine, Imperial College London.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 21 October 2009, 12:30-13:30

Immunology in Pathology

HPV vaccines – will they do their job?

Host: Jim Kaufman (jfk31@cam.ac.uk)

Professor Margaret Stanley, Dept of Pathology, University of Cambridge.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 14 October 2009, 12:30-13:30

Immunology in Pathology

Lymphoid tales: TNFAIP8 in glucocorticoid killing – E4BP4 and the origin of NK cells

Host: Ashley Moffet (am485@cam.ac.uk)

Dr Hugh Brady, Division of Immunology and Infection, Imperial College London.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Monday 12 October 2009, 12:30-13:30

Immunology in Pathology

A journey through parasite genetics in search of protective antigens

Host: Jim Kaufman (jfk31@cam.ac.uk)

Dr Adrian Smith, Dept of Zoology, University of Oxford.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 07 October 2009, 12:30-13:30

Immunology in Pathology

Human NK Cell Receptor Diversity Shaped by Natural Selection

Host: John Trowsdale (jt233@cam.ac.uk)

Dr. Paul Norman, Stanford University.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 24 June 2009, 12:30-13:30

Immunology in Pathology

CD22 and Siglec-G: Two inhibitory receptors on B cells with distinct functions

Host: John Trowsdale (jt233@cam.ac.uk)

Professor Lars Nitschke, University of Erlangen, Germany.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 17 June 2009, 12:30-13:30

Immunology in Pathology

Notch and peripheral immunity

Host: Chris Rudd (cer51@hermes.cam.ac.uk)

Prof. Maggie Dahlman, Faculty of Natural Sciences, Imperial College London.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 10 June 2009, 12:30-13:30

Immunology in Pathology

The global circulation of seasonal influenza viruses

Host: Jim Kaufman (jfk31@cam.ac.uk)

Dr. Colin Russell, Department of Zoology, University of Cambridge.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 03 June 2009, 12:30-13:30

Immunology in Pathology

Regulatory T cells inhibit antigen-dependent T cell function but not bystander T cell activity: implications for pathogenesis of RA

Host: Helga Schneider (hs383@cam.ac.uk)

Professor Fionula Brennan, Kennedy Institute of Rheumatology, Imperial College London.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 27 May 2009, 12:30-13:30

Immunology in Pathology

Why does HLA-B27 predispose to autoimmune Spondyloarthritis?

Host: John Trowsdale (jt233@cam.ac.uk)

Dr Paul Bowness, MRC Human Immunology Unit, Institute of Molecular Medicine, University of Oxford.

Lecture Theatre, Department of Pathology, Tennis Court Road.

Wednesday 20 May 2009, 12:30-13:30