University of Cambridge > > Immunology in Pathology > HIV microbicides: current and emerging candidates

HIV microbicides: current and emerging candidates

Add to your list(s) Download to your calendar using vCal

If you have a question about this talk, please contact Prof. Jim Kaufman.

Host: Chris Rudd (

My main research interest is early events in infection at mucosal surfaces and particularly microbial attachment to host receptors with the aim of developing approaches to prevent infection. Having previously worked on Streptococcus mutans and Helicobacter pylori, my focus now is the development of compounds (microbicides) which can be applied topically to prevent infection with HIV -1. For the last 6 years, I have been coordinating a project (European Microbicides Project, EMPRO ) with 25 partner institutions funded by the European Commission to develop novel microbicides. These include both HIV -1 entry-inhibitors such (e.g. single-domain antibodies, RANTES analogues and CD4 mimetics) as well as small molecule inhibitors of events post HIV entry. I will present some of the findings from this project including data from in vivo efficacy studies as well more detailed analyses of DC-SIGN enhancement of HIV -1 entry.

This talk is part of the Immunology in Pathology series.

Tell a friend about this talk:

This talk is included in these lists:

Note that ex-directory lists are not shown.


© 2006-2024, University of Cambridge. Contact Us | Help and Documentation | Privacy and Publicity