Lecture 15 (University of Cambrdige). Polymer model, mean looping time and interpretation of Hi-C data (Enounter frequencies data)
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SDB - Stochastic dynamical systems in biology: numerical methods and applications
In this talk, I will present the computation of the mean time for a Rouse polymer to loop in free and confined domains. The results are used to extract information (such the radius of confinement) from Hi-C data for the chromatin organization. The methods is based on the asymptotic analysis of the Fokker-Planck equation.
This talk is part of the Isaac Newton Institute Seminar Series series.
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