Orthologous networks in biological systems

Add to your list(s) Download to your calendar using vCal

• Dr Christopher Penfold (Warwick)
• Wednesday 11 February 2015, 11:00-12:00
• Engineering Department, CBL Room BE-438..

If you have a question about this talk, please contact Zoubin Ghahramani.

How an organism develops and responds to environmental stress is influenced by its gene regulatory network (GRN). Here I outline nonparametric Bayesian approaches to network inference based upon Gaussian processes, that allows networks to be inferred from multiple time series transcriptomic datasets. These approaches have proven to be highly successful at identifying important regulators in a variety of processes in Arabidopsis thaliana. Furthermore, these methods address another key challenge in network inference: how to infer networks from multiple datasets when the underlying networks are expected to be similar, but non-identical. This may be the case when networks are rewired in different treatments (treatment specific networks), where network differences arise due to genetic differences (individual or patient specific networks) and (iii) where data is collected in different but related species.

This talk is part of the Machine Learning @ CUED series.

This talk is included in these lists:

• Seminar
• All Talks (aka the CURE list)
• Biology
• CBL important
• Cambridge Centre for Data-Driven Discovery (C2D3)
• Cambridge Forum of Science and Humanities
• Cambridge Language Sciences
• Cambridge Neuroscience Seminars
• Cambridge talks
• Chris Davis' list
• Creating transparent intact animal organs for high-resolution 3D deep-tissue imaging
• Engineering Department, CBL Room BE-438.
• Featured lists
• Guy Emerson's list
• Hanchen DaDaDash
• Inference Group Summary
• Information Engineering Division seminar list
• Interested Talks
• Joint Machine Learning Seminars
• Life Science
• Life Sciences
• ML
• Machine Learning @ CUED
• Machine Learning Summary
• Neuroscience
• Neuroscience Seminars
• Neuroscience Seminars
• Required lists for MLG
• Simon Baker's List
• Stem Cells & Regenerative Medicine
• Trust & Technology Initiative - interesting events
• bld31
• dh539
• kt532's list
• ndk22's list
• ob366-ai4er
• rp587
• yk373's list

Note that ex-directory lists are not shown.