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Large scale organization of chromatin

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Topological Dynamics in the Physical and Biological Sciences

In the cell nucleus chromosomes have a complex architecture serving vital functional purposes. One of the current key open problem concerns the principles which orchestrate their 3D structure. We discuss a model of the molecular mechanisms of chromatin self- organization which we compare against available FISH and Hi-C data.

This talk is part of the Isaac Newton Institute Seminar Series series.

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