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Computational Neuroscience Journal Club

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Andrey Stoychev will cover:

• Mutual inhibition of lateral inhibition: a network motif for an elementary computation in the brain

• Minoru Koyama, Avinash Pujala

• Current Opinion in Neurobiology (2018)

https://www.sciencedirect.com/science/article/pii/S095943881730291X?via%3Dihub

Abstract: A series of classical studies in non-human primates has revealed the neuronal activity patterns underlying decision-making. However, the circuit mechanisms for such patterns remain largely unknown. Recent detailed circuit analyses in simpler neural systems have started to reveal the connectivity patterns underlying analogous processes. Here we review a few of these systems that share a particular connectivity pattern, namely mutual inhibition of lateral inhibition. Close examination of these systems suggests that this recurring connectivity pattern (‘network motif’) is a building block to enforce particular dynamics, which can be used not only for simple behavioral choice but also for more complex choices and other brain functions. Thus, a network motif provides an elementary computation that is not specific to a particular brain function and serves as an elementary building block in the brain.

This talk is part of the Computational Neuroscience series.

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