Scaling of tissue proportions to body size during vertebrate development

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• Dr Patrick Mueller, Friedrich Miescher Laboratory of the Max Planck Society, Tübingen, Germany
• Thursday 08 February 2018, 14:00-15:00
• Part II Room, Department of Genetics, Downing Site.

If you have a question about this talk, please contact Caroline Newnham.

Host: Alfonso Martinez Arias

Extracellular signals pattern tissues by instructing cells to acquire specific fates during embryogenesis. The spatial range of signals must adjust to the size of the embryo, because small and large embryos give rise to proportionately patterned adults, but it has remained unclear how this is achieved during early vertebrate development. I will present our recent quantitative experiments and mathematical modeling of scale-invariant patterning, revealing a novel mechanism that controls the spatial range of patterning signals in differently sized vertebrate embryos.

This talk is part of the Genetics Seminar series.

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