Developing tools to map the brain at synaptic resolution

Add to your list(s) Download to your calendar using vCal

• Marta Costa (Dept. Genetics) and Philipp Schlegel (Dept. Zoology / L.M.B)
• Wednesday 07 December 2016, 18:30-20:00
• Postdoc Centre, 16 Mill Lane.

If you have a question about this talk, please contact Mark Dunning.

The Drosophila mushroom body (MB) is a complex neuropil, used as a model for associative memory storage and state-dependent behaviours. In an international effort, we are generating a wiring diagram of the MB and MB-associated neurons at synaptic resolution using an electron microscopy volume of the entire fruit fly brain. In order to manage a project on this scale, analytic tools have been developed to manage and analyse massive amounts of data.

One of these is NBLAST , a neuron similarity algorithm that compares the shape and position of two neurons, and returns a similarity score. NBLAST is able to distinguish neuron types and identify new ones. NBLAST can also be used to organise large datasets of neurons into groups of similar ones, making it easier to deal with big volumes of data.

We will describe the MB project, touching on technical challenges, the NBLAST algorithm, and its available resources.

This talk is part of the "Life Sciences Masterclass" series.

This talk is included in these lists:

• "Life Sciences Masterclass"
• Cambridge Centre for Data-Driven Discovery (C2D3)
• Cambridge talks
• Chris Davis' list
• Featured lists
• Featured talks
• Guy Emerson's list
• Interested Talks
• PMRFPS's
• Postdoc Centre, 16 Mill Lane
• Trust & Technology Initiative - interesting events
• bld31
• custom
• ndk22's list
• ob366-ai4er
• rp587
• se393's list

Note that ex-directory lists are not shown.