University of Cambridge > Talks.cam > Isaac Newton Institute Seminar Series > How to untie it-translocation of a knotted protein through a pore

How to untie it-translocation of a knotted protein through a pore

Add to your list(s) Download to your calendar using vCal

If you have a question about this talk, please contact Mustapha Amrani.

Topological Dynamics in the Physical and Biological Sciences

Proteins need to be unfolded when translocated through the pores in mitochondrial and other cellular membranes. Knotted proteins, however, might get stuck during this process since the diameter of the pore is smaller than the size of maximally tightened knot. We report the result of computer simulations of knotted protein translocation, which show how the protein can avoid the topological traps and untie its knot during the translocation

This talk is part of the Isaac Newton Institute Seminar Series series.

Tell a friend about this talk:

This talk is included in these lists:

Note that ex-directory lists are not shown.

 

© 2006-2021 Talks.cam, University of Cambridge. Contact Us | Help and Documentation | Privacy and Publicity