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The development and structure of the insect cuticle

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How does the Drosophila skin withstand the internal hydrostatic pressure? The skin of the fruit fly Drosophila melanogaster produces an extracellular matrix, the cuticle that among others serves as an exoskeleton withstanding the internal hydrostatic pressure and thereby allowing locomotion. The cuticle elements responsible for this function and their assembly have been unidentified before we stumbled on it. In my presentation, I will report on Alas and Schlaff that are two essential components constructing and implementing, respectively, the skeletal property of the cuticle.

This talk is part of the Genetics Seminar Series series.

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