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Illuminating diverse RNA silencing pathways using the Arabidopsis Argonautes

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Argonaute (AGO) proteins bind small RNA molecules and are the effectors of RNA silencing. Arabidopsis thaliana has 10 AGO proteins. We have used a combination of AGO immunoprecipitation, sRNA cloning, high throughput sequencing and EST tag sequencing to uncover diverse RNA silencing pathways present in Arabidopsis. The talk will present an overview of known AGO function and relay our current understanding of one AGO (AGO5) that contributes to regulating promoter-associated non-coding RNAs and epigenetic marks.

This talk is part of the Plant Sciences Research Seminars series.

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