University of Cambridge > Talks.cam > Graduate Programme in Cognitive and Brain Sciences > From impulsivity to compulsivity: cross-species studies in humans and other animals relevant to neuropsychiatric disorders.

  Browse A-Z

Log in

Cambridge users (raven)details Other usersdetails No account?details

Information on

Subscribing to talksdetails Finding a talkdetails Adding a talkdetails Disseminating talksdetails Help and Documentationdetails

From impulsivity to compulsivity: cross-species studies in humans and other animals relevant to neuropsychiatric disorders.

Add to your list(s) Download to your calendar using vCal

If you have a question about this talk, please contact Mandy Carter.

This lecture will focus on the utility of the impulsivity and compulsivity constructs for addiction, attention deficit/hyperactivity disorder (ADHD) and obsessive-compulsive disorder OCD ), based on analyses of their neuropsychological and neurochemical basis in humans and in other species. Evidence will be reviewed for striatal and prefrontal cortical components of these potential neural endophenotypes, as well as their differential chemical modulation by the ascending arousal systems, including the monoamines and acetylcholine. Evidence will be drawn from studies using techniques ranging from functional and structural MR, positron emission tomography, selective lesions, intra-cerebral infusions and systemic psychopharmacology. These methods are used to study performance in tasks measuring different forms of impulsivity, including the stop-signal task, as well as tests of compulsivity including reversal learning and extra-dimensional set-shifting. The overall theme of the lecture is to illustrate how work in basic cognitive and behavioural neuroscience may be translated into the clinical context.

References

Everitt BJ, Robbins TW (2005) Neural systems of reinforcement for drug addiction: from actions to habits to compulsion. Nature Neuroscience 8, 1481-1489

Robbins TW (2007). Shifting and stopping: fronto-striatal substrates, neurochemical modulation and clinical implications. Philosophical Transactions of The Royal Society B, 362, 917-932

This talk is part of the Graduate Programme in Cognitive and Brain Sciences series.

Tell a friend about this talk:

This talk is included in these lists:

Note that ex-directory lists are not shown.

Other lists

Whiston Society Science Talks Type the title of a new list here Combined TCM Seminars and TCM blackboard seminar listing

Other talks

XZ: X-ray spectroscopic redshifts of obscured AGN Understanding Ellipsis: Corpus, Annotation, Theory The homelands of the plague: Soviet disease ecology in Central Asia, 1920s–1950s Nuclear fuel manufacture at Westinghouse Springfields past, present and future Action Stations! 'The Japanese Mingei Movement and the art of Katazome' 'Politics in Uncertain Times: What will the world look like in 2050 and how do you know? Picturing the Heart in 2020 An SU(3) variant of instanton homology for webs Constructing the virtual fundamental cycle Why Do We Need Another Biography of Hitler?
 

© 2006-2024 Talks.cam, University of Cambridge. Contact Us | Help and Documentation | Privacy and Publicity