Programmed DNA elimination in insects

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• Dr Laura Ross from Institute of Evolutionary Biology, The University of Edinburgh
• Thursday 14 November 2024, 13:00-14:00
• Biffen Lecture theatre and Zoom.

If you have a question about this talk, please contact Caroline Newnham.

Host – John Welch

Under Mendelian inheritance, individuals receive one set of chromosomes from each of their parents, and transmit one set of these chromosomes at random to their offspring. Yet, in thousands of animals Mendel’s laws are broken and the transmission of maternal and paternal alleles becomes unequal. Why such non-Mendelian reproductive systems have evolved repeatedly across the tree of life remains unclear. My lab studies a variety of arthropod species to understand why, when and how the transmission of genes from one generation to the next deviate from Mendel’s laws. We mainly focus on species with Paternal Genome Elimination: Males transmit only those chromosomes they inherited from their mother to their offspring, while paternal chromosomes are excluded from sperm through meiotic drive. I will present recent work aimed at understanding this unusual reproductive strategy, covering a range of topics including the evolution and mechanisms of DNA elimination, genomic imprinting, sex determination and germline-restricted chromosomes.

This talk is part of the Genetics Seminar series.

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