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When The Golden Chain Breaks: Sleep Dysfunction in Neurogenerative Disorder

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Sleep is a core part of our 24-hour day and plays a major role in ensuring normal cognitive functioning, well-being and health. Sleep disruption in neurologically normal people is debilitating. People who work long shifts or night shifts, such as medical personnel or other emergency workers, are particularly affected. But for many patients with neurological disorders, sleep disturbance is part of their lives. Sleep disturbance is recognised as important in depression and anxiety. Yet it has only recently been recognised that sleep disorder may be part of the disease process in neurodegenerative diseases such as Alzheimer’s and Parkinson’s disease. In this talk, Dr Jenny Morton will present evidence that this is also the case for Huntington’s disease. If sleep and circadian disturbance are core symptoms of neurodegenerative diseases, rather than just being a knock-on effect of being unwell, they represent important therapeutic targets.

This talk is part of the SciSoc – Cambridge University Scientific Society series.

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