Lévy walk dynamics in intracellular transport

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• Sergei Fedotov (University of Manchester)
• Thursday 24 March 2022, 10:00-10:30
• Seminar Room 1, Newton Institute.

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FD2W02 - Fractional kinetics, hydrodynamic limits and fractals

In this talk, we discuss anomalous directional persistence of organelles in human cells in terms of the phenomenon of cumulative inertia: the longer an organelle moves along a microtubule, the less likely it will detach from it. We suggest several non-Markovian models describing  Lévy walk dynamics in intracellular transport.  In particular, we introduce a persistent random walk model with finite velocity and self-reinforcing directionality, which explains how exponentially distributed runs self-organize into truncated Lévy walks observed in active intracellular transport.

This talk is part of the Isaac Newton Institute Seminar Series series.

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