University of Cambridge > Talks.cam > SciSoc – Cambridge University Scientific Society > Structural Bio in the 21st Century

Structural Bio in the 21st Century

Add to your list(s) Download to your calendar using vCal

If you have a question about this talk, please contact rv347.

The tools of structural biology have become more powerful during the last 60 years. The first protein structure, that of sperm whale myoglobin, was solved in 1960 using X-ray crystallography, a method that has grown to produce over 10,000 structures per year, all of them being deposited in the Protein Data Bank (PDB). In recent years, electron cryomicroscopy (cryoEM) of single particles plunge-frozen in a thin film of amorphous ice, has developed rapidly in power and resolution, so that well over 3,000 PDB depositions will be made this year for structures solved by cryoEM. Many of these cryoEM structures represent unstable or flexible assemblies whose structure cannot be determined by any other method, and almost all of them involve images collected on 300 keV state-of-the-art transmission electron cryo-microscopes.

Entry for talks is £3 for non-members and FREE for SciSoc Members! Get a membership today at scisoc.com 🥳

This talk is part of the SciSoc – Cambridge University Scientific Society series.

Tell a friend about this talk:

This talk is included in these lists:

Note that ex-directory lists are not shown.

 

© 2006-2022 Talks.cam, University of Cambridge. Contact Us | Help and Documentation | Privacy and Publicity