Coping with Mechanical Stress: Tissue dynamics in development and repair

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• Dr Yanlan Mao, MRC Laboratory for Molecular Cell Biology, University College London
• Thursday 04 March 2021, 13:30-14:30
• Zoom meeting.

If you have a question about this talk, please contact Caroline Newnham.

Host: Hansong Ma

During growth and development, tissue dynamics, such as tissue folding, cell intercalations and oriented cell divisions, are critical for shaping tissues and organs. However, less is known about how tissues regulate their dynamics during tissue homeostasis and repair, to maintain their shape after development. In this talk, we will discuss how differential growth rates can generate precise folds in tissues. We will also discuss how tissues respond to mechanical perturbations, such as stretching or wounding, by altering their actomyosin contractile structures, to change tissue dynamics, and thus preserve tissue shape and patterning. We combine genetics, biophysics and computational modelling to study these processes.

This talk is part of the Genetics Seminar series.

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