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The development of a motor network in Drosophila, the role of precocious neural activity in the emergence of coordination

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If you have a question about this talk, please contact Philip Sterne.

While neural activity has been shown to be essential to the normal development of connectivity between sensory neurons and their central targets in the brain, little is known about the significance of such early activity for the development of the neural networks underlying movement. Nonetheless many embryos show precocious motor activity, in the form of twitches and incomplete movements. Here we apply a novel technique to the embryo of the fruitfly to show that such precocious activation of the motor system is essential for the normal development of patterns of output that underlie coordinated movement.

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