Approximation of the individual Fisher information matrix and its use in design of population PK/PD studies

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• Leonov, S (GlaxoSmithKline)
• Friday 12 August 2011, 09:45-10:30
• Seminar Room 1, Newton Institute.

If you have a question about this talk, please contact Mustapha Amrani.

Design and Analysis of Experiments

We continue a discussion started at PODE 2010 meeting about different types of approximation of the individual Fisher information matrix and their use in design of population PK/PD studies which are described by nonlinear mixed effects models. We focus on several Monte Carlo-based options and provide examples of their performance.

This talk is part of the Isaac Newton Institute Seminar Series series.

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