A stochastic model of coupled enzymatic degradation

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• Williams, R (UC, San Diego)
• Wednesday 24 March 2010, 09:30-10:30
• Seminar Room 1, Newton Institute.

If you have a question about this talk, please contact Mustapha Amrani.

Stochastic Processes in Communication Sciences

Joint work with Natalie Cookson, Jeff Hasty, Will Mather, Octavio Mondragon-Palomino and Lev Tsimring

A major challenge for systems biology is to deduce the molecular interactions that underly correlations observed between concentrations of different intracellular molecules. While direct explanations such as coupled transcription/translation or direct protein-protein interactions are often considered, potential indirect sources of coupling have received much less attention. In this talk, I will report on an investigation involving both theory and experiment of how correlations can arise generically from a post-translational coupling mechanism involving the processing of multiple protein species by a common enzyme.

This talk is part of the Isaac Newton Institute Seminar Series series.

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