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Mammalian Synthetic Biology – Biomolecular Circuits as Medicine

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  • UserXiaojing Gao, Stanford University
  • ClockMonday 13 February 2023, 14:00-15:00
  • HouseCRUK CI.

If you have a question about this talk, please contact Ciara Adeniyi-Jones.

Dr. Xiaojing Gao is an Assistant Professor of Chemical Engineering from Stanford University. He received a B.S. in Biology from Peking University and a Ph.D. in Biology from Stanford University. He received his postdoctoral training from Biology and Biological Engineering at Caltech. His lab tackles fundamental engineering challenges across different levels of complexity, such as (1) protein components that minimize their crosstalk with human cells and immunogenicity, (2) biomolecular circuits that function robustly in different cells and are easy to deliver, (3) multicellular consortia that communicate through scalable channels, and (4) therapeutic modules that interface with physiological inputs/outputs. Their engineering targets include biomolecules, molecular circuits, viruses, and cells, and their approach combines quantitative experimental analysis with computational simulation. The molecular tools they build will be applied to diverse fields such as immunology, neurobiology, and cancer therapy. In this talk, Xiaojing will share their recently developed tools for controlling protein secretion and sensing RNA in living cells, and the applications they envision for basic research and therapeutics.

This talk is part of the Seminars on Quantitative Biology @ CRUK Cambridge Institute series.

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