Autoencoders and Causality in the Light of Drug Repurposing for COVID-19

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• Caroline Uhler (Massachusetts Institute of Technology)
• Tuesday 23 November 2021, 15:00-16:00
• Seminar Room 1, Newton Institute.

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MDLW04 - The power of women in deep learning

Massive data collection holds the promise of a better understanding of complex phenomena and ultimately, of better decisions. An exciting opportunity in this regard stems from the growing availability of perturbation / intervention data (for example in genomics, advertisement, education, etc.). In order to obtain mechanistic insights from such data, a major challenge is the development of a framework that integrates observational and interventional data and allows causal transportability, i.e., predicting the effect of yet unseen interventions or transporting the effect of interventions observed in one context to another. I will propose an autoencoder framework for this problem. In particular, I will characterize the implicit bias of overparameterized autoencoders and show how this links to causal transportability and can be applied for drug repurposing in the current COVID -19 crisis.

This talk is part of the Isaac Newton Institute Seminar Series series.

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