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Modelling virus infections in the context of cancer therapies (and other diseases)

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IDPW04 - Within-Host Modelling

Over the past years oncolytic viruses have generated much interest in cancer therapy, mainly due to the fact that once a virus is injected into the patient it can actively search for cancer cells and destroy them. However, the anti-tumour effect of oncolytic viruses is greatly diminished by anti-viral immune responses (both innate and adaptive responses), as well as by physical barriers inside the tumour. 
Using various single-scale and multi-scale mathematical modelling approaches, we will investigate the delicate balance between anti-viral and anti-tumour immune responses in the context of virus-tumour-immune interactions.





This talk is part of the Isaac Newton Institute Seminar Series series.

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