cancer

House Online - Google Meet.

Role of cellular senescence in cancer and ageing: therapeutic opportunities

These talks are aimed at Masters and first year PhD students but all are welcome to attend.

User Dr Daniel Munoz-Espin, Group Leader, Department of Oncology..

Thursday 18 June 2020, 09:30-10:30

House Online - Google Meet.

The promise of proton therapy in Paediatric tumours

These talks are aimed at first year PhD students but all are welcome to attend.

User Dr Thankamma Ajithkumar, Cambridge University Hospitals NHS Foundation Trust.

Thursday 11 June 2020, 09:30-10:30

The clinical and biological basis of prostate cancer - from diagnosis to personalised therapy

These talks are aimed at Masters and first year PhD students but all are welcome to attend.

User Mr Vincent Gnanapragasam, Department of Surgery, Cambridge University Hospitals NHS Foundation Trust.

Thursday 04 June 2020, 09:30-10:30

Artificial Intelligence for identifying novel therapeutic targets, biomarkers and drug repositioning opportunities

These talks are aimed at Masters and first year PhD students but all are welcome to attend.

User Dr Namshik Han, Head of Computational Biology, Milner Therapeutics Institute.

Thursday 28 May 2020, 09:30-10:30

Paediatric Malignancies

These talks are aimed at Masters and first year PhD students but all are welcome to attend.

User Dr Amos Burke, Clinical Consultant - Department of Paediatric Haematology, Oncology and Palliative Care.

Thursday 21 May 2020, 09:30-10:30

Treatment of kidney cancer

These talks are aimed at Masters and first year PhD students but all are welcome to attend.

User Mr Grant Stewart, Cambridge University Hospitals.

Thursday 14 May 2020, 09:30-10:30

The role of transcription factors in cancer

These talks are aimed at first year PhD students but all are welcome to attend.

User Prof Jason Carroll, CRUK Cambridge Institute.

Seminars on Quantitative Biology @ CRUK Cambridge Institute

Thursday 07 May 2020, 09:30-10:30

CANCELLED

User Dr Sarah McClelland from Barts Cancer Institute in London.

House CRUK CI Lecture Theatre (Room 001).

Monday 04 May 2020, 13:00-14:00

Epidemiology of Ovarian Cancer

These talks are aimed at first year PhD students but all are welcome to attend.

User Professor Paul Pharoah, Professor of Genetic Epidemiology .

Thursday 30 April 2020, 09:30-10:30

Mathematical and evolutionary approaches to cancer

These talks are aimed at Masters and first year PhD students but all are welcome to attend.

User Jamie Blundell, Early Detection Programme, Dept of Oncology.

Thursday 23 April 2020, 09:30-10:30

DNA repair: from mechanistic insights to therapeutic applications in cancer

These talks are aimed at first year PhD students but all are welcome to attend.

User Professor Steve Jackson, The Gurdon Institute.

Thursday 09 April 2020, 09:30-10:30

House Sackler Lecture Theatre (Level 7), Cambridge Institute for Medical Research.

CANCELLED - “Cancer genomics: from chromatin structure to new therapeutic targets”

Host: Sakari Vanharanta

User Professor Elisa Oricchio (EPFL, Zurich).

Tuesday 07 April 2020, 11:30-12:30

House Clinical School William Harvey Lecture Theatre.

The microenvironment in the myeloid malignancies

These talks are aimed at Masters and first year PhD students but all are welcome to attend.

User Dr Simon Mendez-Ferrer, Department of Haematology.

Thursday 02 April 2020, 09:30-10:30

House Clinical School William Harvey Lecture Theatre.

Breast cancer: demographics, presentation, diagnosis & patient pathway

These talks are aimed at Masters and first year PhD students but all are welcome to attend.

User Dr Richard Baird, Department of Oncology.

Thursday 26 March 2020, 09:30-10:30

Biological and Clinical Features of High Grade Serous Ovarian Cancer

These talks are aimed at first year PhD students but all are welcome to attend.

User Dr James Brenton, CRUK Cambridge Institute.

Thursday 19 March 2020, 09:30-10:30

The development of cancer risk susceptibility models and application to early detection

These talks are aimed at first year PhD students but all are welcome to attend.

User Professor Antonis Antoniou, Early Detection Programme.

Thursday 12 March 2020, 09:30-10:30

Introduction to the early detection of cancer and novel interventions

These talks are aimed at first year PhD students but all are welcome to attend.

User Professor Rebecca Fitzgerald, Early Detection Programme.

Thursday 05 March 2020, 09:30-10:30

Oncological Imaging: introduction and non-radionuclide techniques & radionuclide techniques

These talks are aimed at first year PhD students but all are welcome to attend.

User Dr. Ferdia Gallagher Department of Radiology & Dr Luigi Aloj, Department of Nuclear Medicine, Cambridge University Hospitals NHS Foundation Trust.

Thursday 27 February 2020, 09:30-10:30

The challenges in therapeutic targeting of the RAF-MEK-ERK signalling pathway

User Dr Simon Cook, Babraham Institute.

Thursday 20 February 2020, 09:30-10:30

The AKT inhibitor Capivasertib (AZD5363): From Discovery to Clinical Proof of Concept

These talks are aimed at first year MRes/PhD students but all are welcome to attend.

User Dr Barry Davies - Director, Clinical and Translational Scientific Alliances, AstraZeneca.

Thursday 13 February 2020, 09:30-10:30

A scientists guide to the art of radiation therapy & Neurosurgery for the Oncologist

These talks are aimed at first year PhD students but all are welcome to attend.

User Dr Raj Jena, Department of Onocology and Mr Adel Helmy, Department of Clinical Neuroscience CUH NHS Foundation Trust.

Thursday 23 January 2020, 09:30-10:30

Cancer Immunotherapy

These talks are aimed at Masters and first year PhD students but all are welcome to attend.

User Dr Christine Parkinson, Department of Oncology, Cambridge University Hospitals NHS Foundation Trust.

Thursday 16 January 2020, 09:30-10:30

Systemic anticancer therapy

These talks are aimed at Masters and first year PhD students but all are welcome to attend.

User Dr Gary Doherty (University of Cambridge).

Thursday 09 January 2020, 10:00-11:00

Exploring the role of the tumour microenvironment: what do other cells do?

These talks are aimed at Masters and first year PhD students but all are welcome to attend.

User Dr Jacqui Shields - MRC Cancer Unit.

Thursday 12 December 2019, 09:30-10:30

House Sackler Lecture Theatre (Level 7), Cambridge Institute for Medical Research.

‘Cell Plasticity in Colon Carcinogenesis’

Host: Grad Student Society -

User Professor Dr Florian Greten, Institute for Tumor Biology and Experimental Therapy, Frakfurt.

Tuesday 03 December 2019, 11:30-12:30

Cancer stem cells, evolution and heterogeneity

These talks are aimed at first year PhD students but all are welcome to attend.

User Professor Brian Huntly, Department of Haematology.

Thursday 28 November 2019, 09:30-10:30

Cancer metabolism, a hallmark of cancer- NB 9am start time

These talks are aimed at first year PhD students but all are welcome to attend.

User Dr Christian Frezza, MRC Cancer Unit.

Thursday 21 November 2019, 09:00-10:00

Introduction to the biology of metastasis

These talks are aimed at first year PhD students but all are welcome to attend.

User Dr Sakari Vanharanta, MRC Cancer Unit.

Thursday 14 November 2019, 09:30-10:30

The mutations that drive cancer

These talks are aimed at first year PhD students but all are welcome to attend.

User Dr Paul Edwards, Emeritus Reader in Cancer Biology.

Thursday 07 November 2019, 09:30-10:30

Overview of the core ideas in cancer research

These talks are aimed at first year PhD students but all are welcome to attend.

User Dr Paul Edwards, Emeritus Reader in Cancer Biology.

Thursday 31 October 2019, 09:30-10:30

Tumour structure and nomenclature

These talks are aimed at Masters and first year PhD students but all are welcome to attend.

User Dr Paul Edwards, Emeritus Reader in Cancer Biology.

Thursday 24 October 2019, 09:30-10:30

House Sackler Lecture Theatre (Level 7), Cambridge Institute for Medical Research.

‘Activation of transcription factor Nrf2 as a strategy to restore the cellular redox and protein homeostasis’

Host: Christian Frezza (CF366@hutchison-mrc.cam.ac.uk)

User Professor Albena Dinkova-Kostova,Jacqui Wood Cancer Centre, Division of Cellular Medicine, University of Dundee .

Tuesday 01 October 2019, 11:30-12:30

House Sackler Lecture Theatre (Level 7), Cambridge Institute for Medical Research.

‘Treatment of cancer by inhibition of mtDNA gene expression’

Host: Christian Frezza - (Hutchison/MRC Research Centre Seminar)

User Nils-Göran Larsson, MD, PhD, Professor, Department of Medical Biochemistry and Biophysics (MBB), Karolinska Institutet, Stockholm .

Tuesday 03 September 2019, 11:30-12:30

MicroRNAs as circulating biomarkers in cancer

User Dr Matthew Murray - Academic Consultant Paediatric Oncologist.

Thursday 25 July 2019, 09:30-10:30

Diagnostics and patient pathways in pancreatic cancer

These talks are aimed at first year PhD students but all are welcome to attend.

User Dr Raaj Praseedom - Consultant HPB-Transplant Surgeon, Lead clinician for the East of England Specialist HPB Specialist Multidisciplinary Team..

Thursday 11 July 2019, 09:30-10:30

House Sackler Lecture Theatre (Level 7), Cambridge Institute for Medical Research.

‘Combining omics data and biological knowledge to understand and treat cancer’

Host: Christian Frezza

User Julio Saez-Rodriguez, Heidelberg University, Faculty of Medicine & EMBL- Heidelberg University Molecular Medicine Partnership Unit.

Wednesday 10 July 2019, 11:30-12:30

House Sackler Lecture Theatre (Level 7), Cambridge Institute for Medical Research.

‘Combining omics data and biological knowledge to understand and treat cancer’

Host: Christian Frezza

User Julio Saez-Rodriguez, Institute for Tumor Biology and Experimental Therapy Frankfurt.

Monday 01 July 2019, 11:30-12:30

Cellular signalling networks in colon cancer and the models to study them. A basic research perspective

These talks are aimed at first year PhD students but all are welcome to attend.

User Dr Marc de la Roche, Lecturer - Department of Biochemistry.

Thursday 27 June 2019, 09:30-10:30

The childhood cancer genome

These talks are aimed at first year PhD students but all are welcome to attend.

User Dr Sam Behjati - Research Fellow in Medical Sciences and Wellcome Trust Intermediate Clinical Fellow, Department of Paediatrics and WTSI.

Thursday 20 June 2019, 09:30-10:30

House Clinical School - Seminar room 10.

‘Why Standard Naming and Pixel-based Contouring/Voluming are important to research in the radiation Oncology area’

Host: Dr Richard Benson (richard.benson@addenbrookes.nhs.uk)

User Prof Andrew Miller, Radiation Oncologist, Illawarra Cancer Care Centre, Wollongong, NSW Australia / Adjunct Professor of Informatics, School of Informatics, University of Wollongong .

Tuesday 11 June 2019, 12:00-13:00

House Sackler Lecture Theatre (Level 7), Cambridge Institute for Medical Research.

‘Next-Generation Biopsies in Gastrointestinal Cancers’

Host: Dr Rebecca Fitzgerald (cf208@mrc-cu.cam.ac.uk)

User Dr Nicola Valeri, Institute of Cancer Research and The Royal Marsden NHS Trust.

Tuesday 11 June 2019, 11:30-12:30

Brain tumours: demographics, presentation, diagnosis, treatment

These talks are aimed at first year PhD students but all are welcome to attend.

User Mr Thomas Santarius, Cambridge University Hospitals NHS Foundation Trust.

Thursday 30 May 2019, 09:30-10:30

Kidney cancer: the most lethal urological malignancy

These talks are aimed at first year PhD students but all are welcome to attend

User Dr Grant Stewart, Department of Surgery, Cambridge University Hospitals NHS Foundation Trust.

Thursday 09 May 2019, 09:30-10:30

House Sackler Lecture Theatre (Level 7), Cambridge Institute for Medical Research.

‘New protagonists of the tumour microenvironment’

Host: Sujath Abbas - sa837@mrc-cu.cam.ac.uk (Grad Student Society)

User Dr Ilaria Malanchi, Tumour-Host Interaction Lab,Francis Crick Institute, London .

Tuesday 07 May 2019, 11:30-12:30

House Sackler Lecture Theatre (Level 7), Cambridge Institute for Medical Research.

‘Mammary epithelial cell fate and tumour initiation at the single cell resolution’

Host: Rebecca Fitzgerald

User Walid Khaled, Department of Pharmacology, University of Cambridge.

Tuesday 09 April 2019, 11:30-12:30

The bone marrow microenvironment in myeloid malignancies

These talks are aimed at first year PhD students but all are welcome to attend.

User Dr Simon Mendez-Ferrer (University of Cambridge).

Thursday 28 March 2019, 09:30-10:30

Demographics, Diagnosis and Treatment Pathways in Haematological Malignancies

These talks are aimed at first year PhD students but all are welcome to attend.

User Professor Brian Huntly, Department of Haematology.

Thursday 21 March 2019, 09:30-10:30

Lecture Cancelled

User Lecture Cancelled.

Thursday 14 March 2019, 09:30-10:30

Liquid biopsy biomarkers for early detection; general principles and specific examples

These talks are aimed at first year PhD students but all are welcome to attend.

User Dr Charlie Massie, Early Detection Programme.

Thursday 28 February 2019, 09:30-10:30

House Clifford Albutt Lecture theatre, Clinical School.

‘Multi-dimensional cancer-immune cell interaction during metastasis’

Host: Sakari Vanharanta (SV358@MRC-CU.cam.ac.uk)

User Xiang Zhang, Baylor College of Medicine, Houston, USA.

Wednesday 27 February 2019, 12:00-13:00

Lecture Cancelled

User Louisa Bellis (University of Cambridge).

Thursday 07 February 2019, 09:30-10:30

Systemic Anticancer Therapy

These talks are aimed at first year PhD students but all are welcome to attend.

User Dr Bristi Basu, Department of Oncology, Cambridge University Hospitals NHS Foundation Trust.

Thursday 17 January 2019, 09:30-10:30

House Sackler Lecture Theatre (Level 7), Cambridge Institute for Medical Research.

THIS SEMIAR IS NOW CANCELLED - 'Cell Plasticity in Colon Carcinogenesis'

Host: Graduate Student Society (Sujath Abbas)

User Professor Florian Greten, Institute for Tumor Biology and Experimental Therapy, Frankfurt.

Tuesday 15 January 2019, 11:30-12:30

The integrated approach to the diagnosis of haematological malignancies

These talks are aimed at first year PhD students but all are welcome to attend.

User Dr Mike Scott, Department of Haematology, Cambridge University Hospitals NHS Foundation Trust.

Thursday 03 January 2019, 09:30-10:30

House Sackler Lecture Theatre (Level 7), Cambridge Institute for Medical Research.

‘Executable Disease Networks: Reconstruction, Topology, Dynamics’

Host: Ben Hall

User Anna Niarakis, Université Paris-Saclay, Evry, France.

Tuesday 04 December 2018, 11:30-12:30

Introduction to the biology of metastasis

These talks are aimed at first year PhD students but all are welcome to attend.

User Dr Sakari Vanharanta, MRC Cancer Unit .

Thursday 29 November 2018, 09:30-10:30

MicroRNAs as circulating biomarkers in cancer

These talks are aimed at first year PhD students but all are welcome to attend.

User Dr Matthew Murray, Department of Pathology.

Thursday 26 July 2018, 09:30-10:30

Research frontiers and new therapeutic strategies in pancreatic cancer

These talks are aimed at first year PhD students but all are welcome to attend.

User Dr Tobias Janowitz, Department of Oncology.

Thursday 19 July 2018, 09:30-10:30

Diagnostics and patient pathways in pancreatic cancer

User Mr Raaj Praseedom, Cambridge University Hospitals NHS Foundation Trust.

Thursday 12 July 2018, 09:30-10:30

Lung Cancer. Part 1. Patient pathway and Intervention. Part 2. Lung Cancer: Futurescape

*PLEASE NOTE 09.00 START TIME. These talks are aimed at first year PhD students but all are welcome to attend.

User Dr Robert Rintoul, CUH and Papworth NHS Foundation Trusts, and Dr Frank McCaughan, Department of Biochemistry.

Thursday 05 July 2018, 09:00-10:00

Colorectal cancer. Part 1. Presentation, Diagnosis and Intervention. Part 2. Cellular signalling networks in colon cancer and the models to study them - a basic research perspective

These talks are aimed at first year PhD students but all are welcome to attend.

User Mr Simon Buczacki, CRUK Cambridge Institute and Dr Marc de la Roche, Department of Biochemistry.

Thursday 28 June 2018, 09:30-10:30

Frontiers in paediatric cancer research

These talks are aimed at first year PhD students but all are welcome to attend.

User Dr Suzanne Turner, Department of Pathology.

Thursday 21 June 2018, 09:30-10:30

House Sackler Lecture Theatre (Level 7), Cambridge Institute for Medical Research.

‘Nuclear Mechanopathology & Early Cancer Diagnostics’

Host: Ashok Venkitaraman ((Hutchison/MRC Research Centre Seminar) Contact:pa-venkitaraman@mrc-cu.cam.ac.uk

User Professor GS Shivashankar, Deputy Director, Mechanobiology Institute, National University of Singapore.

Friday 15 June 2018, 10:30-11:30

Paediatric malignancies: an overview

These talks are aimed at first year PhD students but all are welcome to attend.

User Dr Amos Burke, Department of Paediatric Haematology, Oncology and Palliative Care, Cambridge University Hospitals NHS Foundation Trust.

Thursday 14 June 2018, 09:30-10:30

House Sackler Lecture Theatre (Level 7), Cambridge Institute for Medical Research.

‘Cellular Plasticity in Cancer: driving force and therapeutic target’

Host: Sakari Vanharanta (SV358@MRC-CU.cam.ac.uk) Hutchison/MRC Seminar

User Professor Thomas Brabletz, Department of Experimental Medicine, University Erlangen-Nuernberg.

Tuesday 05 June 2018, 11:00-12:00

5 selfish reasons to work reproducibly

These talks are aimed at first year PhD students but all are welcome to attend.

User Dr Florian Markowetz, Group Leader, Cancer Research UK Cambridge Institute, University of Cambridge.

Thursday 31 May 2018, 09:30-10:30

House Sackler Lecture Theatre (Level 7), Cambridge Institute for Medical Research.

‘Accelerating the translation of mutational signatures'

Host: Professor Ashok Venkitaraman (Hutchison/MRC Research Centre Seminar) Contact:pa-venkitaraman@mrc-cu.cam.ac.uk

User Dr Serena Nik-Zainal, Wellcome Sanger Institute.

Thursday 03 May 2018, 11:00-12:00

Translational Science: using biomarkers to guide clinical development in oncology

These talks are aimed at first year PhD students but all are welcome to attend.

User Dr Andy Pierce, AstraZeneca.

Thursday 03 May 2018, 09:30-10:30

Demographics, presentation, diagnosis and patient pathway of haematological malignancies

These talks are aimed at first year PhD students but all are welcome to attend.

User Professor Brian Huntly, Department of Haematology.

Thursday 19 April 2018, 09:30-10:30

Breast cancer - demographics, presentation, diagnosis and patient pathway

These talks are aimed at first year PhD students but all are welcome to attend.

User Dr Charlotte Coles, Department of Oncology, Cambridge University Hospitals NHS Foundation Trust.

Thursday 12 April 2018, 09:30-10:30

House Cambridge Instute Lecture Theatre(CRUK) RobinsonWay Cambridge CB2 0RE.

"Proton Beam Therapy: Current and Future Provision"

Host: Dr Gail Horan

User Yen-Ching Chang, Consultant in Clinical Oncology, UCHL.

Tuesday 20 March 2018, 12:00-13:00

TALK CANCELLED Targets for drug discovery: from target validation to the clinic

These talks are aimed at first year PhD students but all are welcome to attend.

User Dr Paul Smith, AstraZeneca.

Thursday 15 March 2018, 09:30-10:30

Imaging techniques and novel tools for early detection and intervention

These talks are aimed at first year PhD students but all are welcome to attend.

User Dr Sarah Bohndiek and Dr Daniel Munoz-Espin, Early Detection Programme.

Thursday 08 March 2018, 09:30-10:30

House Sackler Lecture Theatre (Level 7), Cambridge Institute for Medical Research.

‘Instituting Molecular Precision in Localised Prostate Cancer - A Cure for All?’

Host: Professor Ashok Venkitaraman

User Rob Bristow, University Professor of Cancer Studies, Director of MCRC.

Tuesday 06 March 2018, 11:30-12:30

Introduction to early detection and tumour development

These talks are aimed at first year PhD students but all are welcome to attend.

User Professor Paul Pharoah and Dr Jamie Blundell, Early Detection Programme.

Thursday 22 February 2018, 09:30-10:30

House Clifford Albutt Lecture theatre, Clinical School.

Oxidative Stress Defences in Cancer

Host: Prof Ashok Venkitaraman (Queries to: AC288@MRC-CU.cam.ac.uk)

User Professor Joan Brugge, Louise Foote Pfeiffer Professor of Cell Biology and Director of the Ludwig Centre at Harvard University.

Tuesday 06 February 2018, 14:30-15:30

DNA repair: from mechanistic insights to therapeutic applications in cancer

These talks are aimed at first year PhD students but all are welcome to attend.

User Professor Steve Jackson, The Gurdon Institute.

Thursday 14 December 2017, 09:30-10:30

House Sackler Lecture Theatre (Level 7), Cambridge Institute for Medical Research.

‘Tracking metabolic reprogramming in cancers with PI3K/Akt activation’

Host: Christian Frezza

User George Poulogiannis, Team Leader, Division of Cancer Biology, Institute of Cancer Research, London.

Tuesday 05 December 2017, 11:30-12:30

Cancer stem cells, evolution and heterogeneity

These talks are aimed at first year PhD students but all are welcome to attend.

User Professor Brian Huntly, Department of Haematology.

Thursday 30 November 2017, 09:30-10:30

Cancer metabolism - a hallmark of cancer

These talks are aimed at first year PhD students but all are welcome to attend.

User Dr Christian Frezza, MRC Cancer Unit.

Thursday 23 November 2017, 09:30-10:30

The mutations that drive cancer

These talks are aimed at first year PhD students but all are welcome to attend.

User Dr Paul Edwards, Emeritus Reader in Cancer Biology.

Thursday 16 November 2017, 09:30-10:30

Overview of the core ideas in cancer research

These talks are aimed at first year PhD students but all are welcome to attend.

User Dr Paul Edwards, Emeritus Reader in Cancer Biology.

Thursday 09 November 2017, 09:30-10:30

House Sackler Lecture Theatre (Level 7), Cambridge Institute for Medical Research.

Metastasis latency: new molecular insights

Host: Sakari Vanharanta

User Roger Gomis, ICREA Research Professor, IRB Barcelona.

Tuesday 07 November 2017, 11:30-12:30

Tumour structure and nomenclature

These talks are aimed at first year PhD students but all are welcome to attend.

User Dr Paul Edwards, Emeritus Reader in Cancer Bioloy.

Thursday 02 November 2017, 09:30-10:30

House Sackler Lecture Theatre (Level 7), Cambridge Institute for Medical Research.

‘The role of Mre11 in DNA double strand break repair - myth and facts’

Host: Ashok Venkitaraman

User Professor Shunichi Takeda, Department of Radiation Genetics, Kyoto University.

Monday 18 September 2017, 14:00-15:00

House Clifford Albutt Lecture theatre, Clinical School.

Satellite RNAs, Heterochromatin and Cancer: A Novel Mechanism of Induction of Breast Cancer by Loss of BRCA1?

Host: Professor Ashok Venkitaraman

User Professor Inder Verma, Salk Institute, San Diego, USA .

Monday 26 June 2017, 15:00-16:00

House Sackler Lecture Theatre (Level 7), Cambridge Institute for Medical Research.

‘Exploring and exploiting aberrant self-fate programs in leukemia’

Host: Sakari Vanharanta (Hutchison/MRC talk)

User Dr Johannes Zuber, Research Institute of Molecular Pathology (IMP), Vienna, Austria.

Tuesday 06 June 2017, 11:30-12:30

House Sackler Lecture Theatre (Level 7), Cambridge Institute for Medical Research.

'Analyses for Rule-Based Models of Cellular Signalling'

SPECIAL COMPUTATIONAL BIOLOGY SEMINAR - Host by: Dr Ben Hall

User Dr Jean Yang, Assistant Professor,Department of Computer Science, Carnegie Mellon University, Pittsburgh USA .

Thursday 25 May 2017, 15:00-16:00

House Sackler Lecture Theatre (Level 7), Cambridge Institute for Medical Research.

‘Alterations of the Polycomb machinery in cancers’

Host: Sakari Vanharanta (Hutchison/MRC talk)

User Raphaël Margueron, Curie Institute, Paris.

Tuesday 02 May 2017, 11:30-12:30

House Sackler Lecture Theatre (Level 7), Cambridge Institute for Medical Research.

‘Non-coding RNA - new roles for old players’

Host: Dr Carla Martins

User Professor Anders Lund, Biotech Research and Innovation Centre, University of Copenhagen.

Tuesday 07 March 2017, 11:30-12:30

House Sackler Lecture Theatre (Level 7), Cambridge Institute for Medical Research.

The interaction between tumor hypoxia and DNA methylation

Host: Professor Ashok Venkitaraman

User Dr Bernard Thienpont, VIB-KU Leuven Center for Cancer Biology, KU Leuven, Belgium.

Tuesday 07 February 2017, 11:30-12:30

CANCELLED - Impact of the Microbiome on cancer and its treatment

Host: Dr Pippa Corrie

User Dr Trevor Lawley, Group Leader, Host-Microbiota Interactions Laboratory, Wellcome Trust Sanger Institute.

Tuesday 29 November 2016, 12:00-13:00

House Sackler Lecture Theatre (Level 7), Cambridge Institute for Medical Research.

"Mechanisms of colon cancer initiation, progression and metastasis"

Host: Sakari Vanharanta (Hutchison/MRC talk)

User Joerg Huelsken, Associate Professor, Debiopharm Chair in Signal Transduction in Oncogenesis, EPFL, Lausanne.

Tuesday 05 July 2016, 11:30-12:30

Mechanisms of lymphomagenesis: Developmental origins of a paediatric cancer

Host Dr Simon Pacey

User Dr Suzanne Turner, Department of Pathology.

Tuesday 28 June 2016, 12:00-13:00

Common germline genetic variation and risk of cancer

User Professor Paul Pharoah, Dept of Oncology, University of Cambridge.

Thursday 16 June 2016, 09:30-10:30

Computational Radiotherapy Symposium, 2016: personalised radiotherapy, or how computers can cure cancer

Organiser: Prof Neil Burnet (jms203@medschl.cam.ac.uk Tel: 01223768433)

User Speakers as detailed in Symposium Programme.

Thursday 09 June 2016, 12:30-17:30

Comparative aspects of canine cancer and therapy

User Dr Jane Dobson, Dept of Veterinary Medicine, University of Cambridge.

Thursday 09 June 2016, 09:30-10:30

Surgery and prostate cancer

User Mr Adam Nelson, CRUK CI and Cambridge University Hospitals.

Thursday 02 June 2016, 09:30-10:30

Cancer immunotherapy

User Dr Robert Wilkinson, MedImmune.

Thursday 19 May 2016, 09:30-10:30

Future of medicines development: capabilities and how industry is evolving and interacting with academia and the NHS

Host: Dr Jean Abraham

User Andrew Hughes, Professor of Experimental Cancer Medicine,The Christie NHS Foundation Trust, Manchester.

Tuesday 17 May 2016, 12:00-13:00

Treatment of lung cancer

User Dr Susan Harden, Cambridge University Hospitals.

Thursday 12 May 2016, 09:30-10:30

House Sackler Lecture Theatre (Level 7), Cambridge Institute for Medical Research.

“Mechanisms of MYC-driven genome instability”

Host: Dr Anna Philpott

User Jean Gautier, Professor of Genetic and Development, Institute for Cancer Genetics, Columbia University, New York (USA).

Tuesday 03 May 2016, 11:30-12:30

Treatment of pancreatic cancer

User Professor Duncan Jodrell, CRUK CI and Cambridge University Hospitals.

Thursday 28 April 2016, 09:30-10:30

Use of surgery in breast cancer treatment

User Mr Parto Forouhi, Cambridge University Hospitals.

Thursday 21 April 2016, 09:30-10:30

DNA damage repair

User Dr Mark O'Connor, AstraZeneca.

Thursday 14 April 2016, 09:30-10:30

Breast cancer

User Professor Carlos Caldas.

Thursday 17 March 2016, 09:30-10:30

“Why Determining Pathogenicity in the Age of Precision Medicine, will Require More than Analyzing Genomic Sequences”

Host: Dr Marc Tischkowitz

User Dr Bruce Gottlieb, Lady Davis Institute for Medical Research, Segal Cancer Centre, Jewish General Hospital, Department of Human Genetics, Department of Medicine, McGill University, Montreal, Canada.

Tuesday 15 March 2016, 12:00-13:00

Prostate cancer

User Dr Vincent Gnanapragasam.

Thursday 10 March 2016, 09:30-10:30

House Berridge Room, Department of Radiology, Level 5.

“New Developments in Molecular Imaging of Prostate Cancer”

Host: Professor Fiona Gilbert

User Professor Wim Oyen, Professor of Nuclear Medicine and Molecular Imaging, ICR, London.

Wednesday 09 March 2016, 17:00-18:00

Innate Genetics and the Tumour Microenvironment Cooperate to Drive Prostate Cancer Aggression

Host: Dr Simon Pacey

User Prof Robert G Bristow, Senior Scientist, Princess Margaret Cancer Centre, Toronto.

Tuesday 23 February 2016, 12:00-13:00

Brain cancer

User Professor Richard Gilbertson.

Thursday 18 February 2016, 09:30-10:30

Ovarian cancer

User Dr Christine Parkinson.

Thursday 11 February 2016, 09:30-10:30

Leukaemia

User Dr Brian Huntly.

Thursday 04 February 2016, 09:30-10:30

Cancer metastasis

User Dr Sakari Vanharanta.

Thursday 28 January 2016, 09:30-10:30

Oesophageal cancer

User Professor Rebecca Fitzgerald.

Thursday 21 January 2016, 09:30-10:30

Colorectal cancer and its management

User Dr Simon Buczacki.

Thursday 14 January 2016, 09:30-10:30

Reproducible Research

User Florian Markowetz, CRUK CI.

Thursday 10 December 2015, 09:30-10:30

‘Combine and conquer: critical pre-clinical and clinical aspects of targeted anti-cancer drugs’

Host: Dr Simon Pacey

User Dr Udai Banerji, Drug Development Unit, ICR.

Tuesday 08 December 2015, 12:00-13:00

Title to be confirmed

User Speaker to be confirmed.

Thursday 03 December 2015, 09:30-10:30

Tumour natural history, structure and nomenclature

User Paul Edwards, Department of Pathology.

Thursday 26 November 2015, 09:30-10:30

"Tumor-induced reprogramming of hepatic metabolism disrupts anti‐tumor immunity”

Host: Dr Simon Pacey

User Dr Tobias Janowitz, Department of Oncology.

Tuesday 24 November 2015, 12:00-13:00

This talk is postponed until Dec 16

User Speaker to be confirmed.

Thursday 19 November 2015, 09:30-10:30

House Sackler Lecture Theatre (Level 7), Cambridge Institute for Medical Research.

Intrinsic and extrinsic determinants of pancreatic cancer stem cells

Host: Hutchison/MRC Research Centre Graduate Student Society

User Professor Christopher Heeschen, Centre Lead, Centre for Stem Cells in Cancer and Ageing, Barts Cancer Institute, London.

Tuesday 17 November 2015, 11:30-12:30

Overview of cancer theoretical framework

User Paul Edwards, Department of Pathology.

Thursday 05 November 2015, 09:30-10:30

Tumour natural history, structure and nomenclature

User Paul Edwards, Department of Pathology.

Thursday 29 October 2015, 09:30-10:30

This talk has been postponed

User Speaker to be confirmed.

Thursday 15 October 2015, 09:30-10:30

Melanoma and the translational cycle of innovation in cancer therapeutics

Host: Dr Pippa Corrie

User Professor Grant McArthur, Peter MacCallum Cancer Centre, Victoria, Australia.

Tuesday 13 October 2015, 12:00-13:00

Genomics of radiation responses and radiosensitivity

Host: Dr Ajithkumar

User Professor Michael McKay, North Coast Cancer Institute, NSW, Australia.

Tuesday 15 September 2015, 12:00-13:00

CANCELLED - "Synergistic effect of radiotherapy and cis-platinum chemotherapy delivered via gold nanoparticles in glioblastoma multiforme"

CANCELLED

User Dr Sara Piccirillo, Department of Clinical Neurosciences and Alexandra Vaideanu, Deptatment of Engineering .

Tuesday 08 September 2015, 12:00-13:00

House Sackler Lecture Theatre (Level 7), Cambridge Institute for Medical Research.

‘Novel dual-action combination therapy enhances angiogenesis whilst reducing tumour growth and spread’

Hosts: Jacqui Shields/Sakari Vanharanta (Hutchison/MRC Research Centre)

User Professor Kairbaan Hodivala-Dilke, Professor of Angiogenesis, Deputy Institute Director QMUL .

Tuesday 07 July 2015, 11:00-12:00

Interrogating the Architecture of Cancer Genomes

Host : Dr Bristi Basu

User Dr Peter Campbell, Head of Cancer Genome Project, Wellcome Trust Sanger Institute..

Tuesday 23 June 2015, 12:00-13:00

'Harnessing hypoxia signalling in cancer'

Host: Dr Simon Pacey

User Professor Margaret Ashcroft, Cambridge Cardiovascular.

Tuesday 09 June 2015, 12:00-13:00

House Sackler Lecture Theatre (Level 7), Cambridge Institute for Medical Research.

'ECM remodelling during cancer progression'

Hosts: Sakari Vanharanta and Jacqui Shields (Hutch)

User Dr Janine Erler, Associate Professor - Biotech Research & Innovation Centre (BRIC),Copenhagen .

Tuesday 02 June 2015, 12:00-13:00

House Sackler Lecture Theatre (Level 7), Cambridge Institute for Medical Research.

DNA damage response: Mechanisms and relevance for cancer development and treatment

Hutchison/MRC Research Centre Seminar - Host: Hutchison/MRC Research Centre Graduate Student Society

User Professor Jiri Bartek, The Danish Cancer Society Research Center Genome Integrity Unit, Denmark.

Tuesday 19 May 2015, 12:00-13:00

"Designing trials to find the right dose"

Host: Dr Simon Pacey

User Dr Adrian Mander - Director of MRC Biostatistics Unit Hub for Trials Methodology Research, Cambridge.

Tuesday 12 May 2015, 12:00-13:00

House Sackler Lecture Theatre (Level 7), Cambridge Institute for Medical Research.

Metastatic Stem Cells, TGF-beta signalling and poor-prognosis in CRC

Hutchison/MRC Research Centre Seminar

User Dr Eduard Batlle (Group Leader, Institute for Research in Biomedicine, Barcelona).

Tuesday 05 May 2015, 12:00-13:00

Defining treatment paradigms in prostate cancer; the UK as a dominant force - past, present, and future

Host: Dr Simon Pacey

User Professor Malcolm Mason, NCRI Prostate Cancer Clinical Studies Group and School of Medicine, Cardiff University.

Tuesday 14 April 2015, 12:00-13:00

Epidemiology

User Paul Pharoah, CRUK Genetic Epidemiology Unit, Strangeways Research Laboratory.

Thursday 05 March 2015, 09:30-10:30

House Sackler Lecture Theatre (Level 7), Cambridge Institute for Medical Research.

Systems Biology of Cancer

Host: Hutchison/MRC Research Centre Graduate Student Society

User Professor Jussi Taipale, Department of Biosciences and Nutrition, Karolinska Institute, Sweden .

Tuesday 03 March 2015, 12:00-13:00

in vivo models

Please note: this talk takes place on WEDNESDAY!

User Suzanne Turner, Department of Pathology.

Wednesday 25 February 2015, 09:30-10:30

Genomic technologies

User Jason Carroll, Cancer Research UK Cambridge Institute.

Thursday 19 February 2015, 09:30-10:30

Computational Biology

This talk was postponed from February 5 2015

User Florian Markowetz, Cancer Research UK Cambridge Institute.

Thursday 12 February 2015, 09:30-10:30

Computational biology

This lecture has been postponed. It will now take place on February 12 at 9:30.

User Florian Markowetz, Cancer Research UK Cambridge Institute.

Thursday 05 February 2015, 09:30-10:30

House Sackler Lecture Theatre (Level 7), Cambridge Institute for Medical Research.

MYC Oncoproteins act as Epigenetic Modifiers

Hutchison/MRC Research Centre Seminar - Host by: Dr Anna Philpott

User Dr Frank Westermann, Research Group Neuroblastoma Genomics, DKFZ, Heidelberg.

Tuesday 03 February 2015, 12:00-13:00

Stem cells and cancer

User Phil Jones, MRC Cancer Unit.

Thursday 29 January 2015, 09:30-10:30

“Optimizing Image Guided Radiotherapy for Patient Benefit”

Host: Professor Neil Burnet

User Dr Peter Remeijer, Medical Physicist NKI /Avl, Amsterdam.

Tuesday 27 January 2015, 12:00-13:00

Senescence, cell death and apoptosis

User Masashi Narita, Cancer Research UK Cambridge Institute.

Thursday 22 January 2015, 09:30-10:30

Metastasis

User Sakari Vanharanta, Department of Oncology.

Thursday 15 January 2015, 09:30-10:30

Explaining the reduction in ovarian cancer mortality 1977 to 2014

Host: Dr Marc Tischkowitz

User Dr Steven Narod, Director, Familial Breast Cancer Research Unit, Women's College Research Institute, Toronto, Canada.

Tuesday 13 January 2015, 12:00-13:00

Ovarian Cancer in Transition

Host: Dr Christine Parkinson

User Mr Douglas Levine, Gynecology Service, Department of Surgery.

Tuesday 16 December 2014, 12:00-13:00

Tumour Metabolism

User Christian Frezza, MRC Cancer Unit.

Thursday 11 December 2014, 09:30-10:30

Oncogenes and tumour suppressors (signalling and pathways)

User Masashi Narita, Cancer Research UK Cambridge Institute.

Thursday 04 December 2014, 09:30-10:30

House Sackler Lecture Theatre (Level 7), Cambridge Institute for Medical Research.

In vivo function-based genomic approaches for cancer drug target discovery

Hutchison/MRC Research Centre Seminar

User Professor Daniel Peeper, Head, Division of Molecular Oncology, The Netherlands Cancer Institute.

Tuesday 02 December 2014, 12:00-13:00

Transcription

User Jason Carroll, Cancer Research UK Cambridge Institute.

Thursday 27 November 2014, 09:30-10:30

Development and the cell cycle

User Anna Philpott, Department of Oncology, MRC-Hutchison Research Centre.

Thursday 20 November 2014, 09:30-10:30

House Sackler Lecture Theatre (Level 7), Cambridge Institute for Medical Research.

Cell fate in response to anti-mitotic chemotherapeutics

Hutchison/MRC Research Centre Seminar (please note unusual date)

User Professor Stephen Taylor, Faculty of Life Sciences, University of Manchester.

Wednesday 19 November 2014, 12:00-13:00

Tracking genomic aberrations of the androgen receptor (AR) in castration-resistant prostate cancer (CRPC)

Host: Dr Simon Pacey

User Dr Gerhardt Attard, Royal Marsden Hospital, London.

Tuesday 18 November 2014, 12:00-13:00

Genetic instability - observation and concepts

User Paul Edwards, Department of Pathology.

Thursday 13 November 2014, 09:30-10:30

“Stratified Medicine in Cancer Therapy - a practical guide”

Host: Dr Nitzan Rosenfeld

User Professor Gary Middleton, Professor in Medical Oncology, School of Cancer Sciences, University of Birmingham.

Tuesday 11 November 2014, 12:00-13:00

Overview of cancer theoretical framework

User Paul Edwards, Department of Pathology.

Thursday 30 October 2014, 09:30-10:30

House CRI Lecture Theatre, Cambridge Research Institute.

"The role of epigenetic regulators and their therapeutic targeting in Acute Myeloid Leukaemia and haematological malignancies”

Host: Professor Duncan Jodrell

User Dr Brian Huntly, Department of Haematology, Cambridge University.

Tuesday 21 October 2014, 12:00-13:00

Tumour natural history, structure and nomenclature (lecture/demonstration)

User Paul Edwards, Department of Pathology.

Thursday 16 October 2014, 09:30-10:30

House CRI Lecture Theatre, Cambridge Research Institute.

CANCELLED - Lung cancer, biomarkers and unanswered questions - a clinical translational perspective

Host: Dr Simon Pacey

User Dr Fiona Blackhall, Consultant Medical Oncologist, The Christie Hospital, Manchester .

Tuesday 14 October 2014, 12:00-13:00

House Sackler Lecture Theatre (Level 7), Cambridge Institute for Medical Research.

The role of stem cells in the pathogenesis of hepato-biliary cancers

Hutchison/MRC Research Centre Seminar

User Professor Nisar Malek, University of Tubingen, Germany.

Tuesday 07 October 2014, 12:00-13:00

“CDD’s new Research Strategy”

Host: Professor Duncan Jodrell

User Dr Nigel Blackburn, Director of Centre for Drug Development, Cancer Research UK.

Tuesday 07 October 2014, 12:00-13:00

House CRI Lecture Theatre, Cambridge Research Institute.

“Paradigm changes produced by targeted agents in Phase I trials in Oncology. Case studies of a TFbeta inhibitor and a Sonic Hedgehog inhibitor”

Host: Dr Richard Baird

User Dr Jordi Rodon, Head of Research Unit for Molecular Therapy of Cancer Oncology Department. Vall D’Hebron University Hospital, Barcelona, Spain.

Tuesday 09 September 2014, 12:00-13:00

House Cancer Research UK Cambridge Institute, Lecture Theatre.

Cellular hierarchies in normal and malignant epithelial tissue

CRUK CI open seminar

User John Stingl, Cancer Research UK Cambridge Institute.

Monday 28 July 2014, 14:45-15:45

House CRI Lecture Theatre, Cambridge Research Institute.

'Scottish Collaboration On Translational Research into Renal Cell Cancer (SCOTRRCC): a springboard for renal cancer biomarker development’.

Host: Professor Tim Eisen

User Mr Grant Stewart, Clinical Senior Lecturer and Honorary Consultant in Urological Surgery, University of Edinburgh .

Tuesday 22 July 2014, 12:00-13:00

Noninvasive cancer genomics

CRUK CI seminar

User Nitzan Rosenfeld, Cancer Research UK Cambridge Institute.

Friday 27 June 2014, 13:45-14:45

Epigenetics and microRNA

This talk has been rescheduled from earlier in the year

User Eric Miska, Wellcome Trust/Cancer Research UK Gurdon Institute.

Thursday 26 June 2014, 09:30-10:30

House CRI Lecture Theatre, Cambridge Research Institute.

Precision Cancer Prevention: Trying to use Genomics to Save Lives

Host: Dr Marc Tischkowitz

User John Hopper, Professor & Director (Research), Centre for Molecular, Environmental, Genetic and Analytic (MEGA) Epidemiology, University of Melbourne, Australia.

Tuesday 24 June 2014, 12:00-13:00

Epidemiology

User Paul Pharoah, Department of Public Health and Primary Care.

Thursday 19 June 2014, 09:30-10:30

MRI and MRS in cancer research and treatment

User John Griffiths, Cancer Research UK Cambridge Institute.

Thursday 12 June 2014, 09:30-10:30

House CRI Lecture Theatre, Cambridge Research Institute.

Breast Imaging research in Cambridge

Host: Dr Richard Baird

User Professor Fiona Gilbert, Head of Department of Radiology, Cambridge.

Tuesday 10 June 2014, 12:00-13:00

Radiotherapy

User Neil Burnet, Department of Oncology.

Thursday 05 June 2014, 09:30-10:30

House Sackler Lecture Theatre (Level 7), Cambridge Institute for Medical Research.

Undermining Myc: Mitochondria Hold the Key

Hutchison/MRC Research Centre Seminar

User Dr Daniel Murphy, Institute of Cancer Sciences, University of Glasgow.

Tuesday 03 June 2014, 12:00-13:00

Metabolism, oxygen and cancer

User John Griffiths, Cancer Research UK Cambridge Institute.

Thursday 29 May 2014, 09:30-10:30

Drug discovery

User Grahame McKenzie, MRC Cancer Unit.

Thursday 22 May 2014, 09:30-10:30

House CRI Lecture Theatre, Cambridge Research Institute.

Personalised Cancer Medicine. How do we get there?

Host: Dr Jean Abraham

User Dr Helena Earl, Dept. of Oncology, University of Cambridge.

Tuesday 20 May 2014, 12:00-13:00

House CRI Lecture Theatre, Cambridge Research Institute.

"From trials evaluating drugs to trials evaluating treatment algorithms – Focus on the SHIVA trial"

Host: Dr Gill Barnett

User Dr Christophe Le Tourneau, Medical Oncologist, Head of the Phase I Program at the Institut Curie, Paris, France,.

Tuesday 13 May 2014, 12:00-13:00

Therapeutics and clinical trials

User Duncan Jodrell, Cancer Research UK Cambridge Institute.

Thursday 08 May 2014, 09:30-10:30

House Sackler Lecture Theatre (Level 7), Cambridge Institute for Medical Research.

Spatio-temporal control of RhoGTPases and the cytoskeleton in invading cancer cells by integrins and endocytic trafficking

Hutchison/MRC Research Centre Seminar

User Dr Patrick Caswell, Wellcome Trust Centre for Cell-Matrix Research, University of Manchester.

Tuesday 06 May 2014, 12:00-13:00

Signal transduction

User Ian Mills, Centre for Molecular Medicine Norway.

Thursday 01 May 2014, 09:30-10:30

Postponed to 22 May Drug discovery

This talk has been postponed until 22 May

User Grahame McKenzie, MRC Cancer Unit.

Thursday 10 April 2014, 09:30-10:30

Centrosome changes in cancer – causes and consequences

CRUK CI guest seminar

User Monica Bettencourt Dias, Instituto Gulbenkian de Ciência.

Wednesday 09 April 2014, 11:00-12:00

House Sackler Lecture Theatre (Level 7), Cambridge Institute for Medical Research.

Targeting bioenergetics in hypoxic and rapidly growing tumours

Hutchison/MRC Research Centre Seminar

User Dr Jacques Pouysseggur, Institute of Research on Cancer and Ageing (IRCAN), Nice, France.

Tuesday 08 April 2014, 12:00-13:00

Postponed to 19 June Epidemiology

Postponed to 19 June

User Paul Pharoah, Department of Public Health and Primary Care.

Thursday 03 April 2014, 09:30-10:30

House CRI Lecture Theatre, Cambridge Research Institute.

“Personalized Medicine in Oncology: The Dutch experience”

Host: Dr Richard Baird

User Professor Jaap Verweij, Erasmus MC Cancer Institute, Weytemaweg 80, 3105 CN Rotterdam, The Netherlands.

Tuesday 01 April 2014, 12:00-13:00

In vivo models

User Suzanne Turner, Department of Pathology.

Thursday 20 March 2014, 09:30-10:30

Genomic technologies

User Jason Carroll, Cancer Research UK Cambridge Institute.

Thursday 13 March 2014, 09:30-10:30

Solid vs. non-solid tumours

Please note change of room, we will meet external attendees in reception and accompany them to the seminar room.

User Brian Huntly, Department of Haematology.

House CRUK CI Room 215.

Thursday 06 March 2014, 09:30-10:30

House Sackler Lecture Theatre (Level 7), Cambridge Institute for Medical Research.

Cell death and autophagy in response to inhibition of glycolysis

Hutchison/MRC Research Centre Seminar

User Dr Cristina Muñoz Pinedo, IDIBELL, Barcelona, Spain.

Tuesday 04 March 2014, 12:00-13:00

Computational biology

Please note change of room, we will meet external attendees in reception and accompany them to the seminar room.

User Florian Markowetz, Cancer Research UK Cambridge Institute.

House CRUK CI Room 215.

Thursday 27 February 2014, 09:30-10:30

Transcriptional regulation and techniques

Please note this talk is on a Wednesday

User Duncan Odom, Cancer Research UK Cambridge Institute.

Wednesday 12 February 2014, 09:30-10:30

House CRI Lecture Theatre, Cambridge Research Institute.

“What can we do to accelerate the discovery of new medicines for patients?”

Host: Dr Bristi Basu

User Professor Chas Bountra, Head of Structural Genomics Consortium, University of Oxford, Nuffield Dept of Clinical Medicine .

Tuesday 11 February 2014, 12:00-13:00

Circulating DNA and diagnostics

User Nitzan Rosenfeld, Cancer Research UK Cambridge Institute.

Thursday 06 February 2014, 09:30-10:30

House Sackler Lecture Theatre (Level 7), Cambridge Institute for Medical Research.

Translating Tumour Metabolism into New Diagnostics and Novel Anti-Cancer Therapeutics

Hutchison/MRC Research Centre Seminar

User Professor Michael Lisanti, Director of the Breakthrough Breast Cancer Research Unit, University of Manchester.

Tuesday 04 February 2014, 12:00-13:00

House CRI Lecture Theatre, Cambridge Research Institute.

Personalized medicine initiative at Gustave Roussy

Host: Dr Richard Baird

User Professor Jean-Charles SORIA - Chef de Service, Professor of Medicine and Medical Oncology, Paris University XI and cancer specialist at Institut Gustave, Roussy..

Tuesday 14 January 2014, 12:00-13:00

House Sackler Lecture Theatre (Level 7), Cambridge Institute for Medical Research.

Chasing metabolic alterations in cancer

Hutchison/MRC Research Centre Seminar

User Dr Arkaitz Carracedo, CIC bioGUNE, (Center for Cooperative Research in Biosciences), Derio, Spain.

Tuesday 07 January 2014, 12:00-13:00

House CRI Lecture Theatre, Cambridge Research Institute.

CANCELLED

Host: Dr Richard Baird

User Prof Josep Tabernero, Head, Medical Oncology Department, Vall d' Hebron University Hospital, Barcelona, Spain.

Tuesday 17 December 2013, 12:00-13:00

Metastasis

User Gill Murphy, Cancer Research UK Cambridge Institute.

Thursday 12 December 2013, 09:30-10:30

Tumour metabolism

User Christian Frezza, MRC Cancer Unit.

Thursday 05 December 2013, 09:30-10:30

House Sackler Lecture Theatre (Level 7), Cambridge Institute for Medical Research.

The autophagy signaling network in the coordination of a cell's response

Hutchison/MRC Research Centre Seminar

User Prof Francesco Cecconi, University of Tor Vergata, Italy .

Tuesday 03 December 2013, 12:00-13:00

House CRI Lecture Theatre, Cambridge Research Institute.

"The Cambridge Breast Cancer Programme"

Host: Dr Richard Baird

User Prof Carlos Caldas, CRUK Cambridge Research Institute.

Tuesday 26 November 2013, 12:00-13:00

Stem cells and cancer

User Phil Jones, MRC Cancer Unit.

Thursday 21 November 2013, 09:30-10:30

Introduction to cancer in Cambridge (BP) followed by Cell cycle and checkpoints (AP)

User Bruce Ponder and Anna Philpott, Department of Oncology.

MRC Cancer Unit Annual Lecture

Thursday 14 November 2013, 09:30-10:30

The p53 pathway: 21 years of the "guardian of the genome"

Refreshments will be available after this talk outside the lecture theatre

User Prof Sir David Lane, Chief Scientist, A*STAR, Singapore.

House Max Perutz Lecture Theatre, MRC Laboratory of Molecular Biology.

Monday 04 November 2013, 16:00-17:30

House CRI Lecture Theatre, Cambridge Research Institute.

CANCELLED - Scottish Collaboration On Translational Research into Renal Cell Cancer, developing a systems medicine approach to personalised treatment

User Mr Grant Stewart, Department of Urology and Edinburgh Urological Cancer Group,Western General Hospital. Edinburgh.

Tuesday 29 October 2013, 12:00-13:00

Development

User Anna Philpott, Department of Oncology.

Thursday 17 October 2013, 09:30-10:30

House CRI Lecture Theatre, Cambridge Research Institute.

Spotlight on Cambridge Clinical Trials; Presentations from the American Society of Oncology (ASCO) Annual Meeting 2013

Host: Dr Simon Pacey

User Prof Tim Eisen, Dr Hugo Ford, Dr Pippa Corrie & Dr Kate Fife.

Tuesday 08 October 2013, 12:00-13:00

House CRI Lecture Theatre, Cambridge Research Institute.

Target-Based Approach in Early-Phase Clinical Trials in Cancer

Host: Dr Richard Baird

User Filip Janku, Investigational Cancer Therapeutics, (Phase I Clinical Trials Program), The University of Texas MD Anderson Cancer Center, Houston.

Tuesday 01 October 2013, 12:00-13:00

CANCELLED

User Professor Charles Swanton, CRUK & UCL Trials Centre, UCL.

Tuesday 24 September 2013, 12:00-13:00

Advances in non-surgical treatment for cervix cancer

User Dr Li Tee Tan, Addenbrooke's .

Tuesday 10 September 2013, 12:00-13:00

House Sackler Lecture Theatre (Level 7), Cambridge Institute for Medical Research.

Insights for the role of tumour-related inflammation and stem cells in Drosophila

Hutchison/MRC Research Centre Seminar

User Dr Marcos Vidal, Beatson Institute, Glasgow .

Tuesday 03 September 2013, 12:00-13:00

House CRI Lecture Theatre, Cambridge Research Institute.

Risk and uncertainty in radiotherapy. Why I am the weakest link?

User Dr Tom Roques, Lead of Head and Neck Cancer Multidisciplinary Team, Norfolk and Norwich Hospital.

Tuesday 16 July 2013, 12:00-13:00

House Sackler Lecture Theatre (Level 7), Cambridge Institute for Medical Research.

Genetic modifiers and microenvironmental control of tumor invasiveness

Hutchison/MRC Research Centre Seminar- Please note unusual time and 1:00pm start

User Prof Douglas Hanahan, EPFL, Switzerland .

Tuesday 02 July 2013, 13:00-14:00

House CRI Lecture Theatre, Cambridge Research Institute.

"Image guidance – benefits and risks"

User Professor Marcel van Herk, Imaging Physicist, Project Leader, The Netherlands Cancer Institute.

Tuesday 25 June 2013, 12:00-13:00

Economics of Cancer Medicines

User Professor Richard Sullivan, Guy's Hospital, London.

Tuesday 11 June 2013, 12:00-13:00

House Sackler Lecture Theatre (Level 7), Cambridge Institute for Medical Research.

Control of cytokinesis and the dark side of actomyosin forces

Hutchison/MRC Research Centre Seminar

User Dr Mark Petronczki, London Research Institute.

Tuesday 04 June 2013, 12:00-13:00

"Renal Cancer and Oxygen Sensing"

User Prof Patrick Maxwell, Regius Professor of Physic, University of Cambridge.

Tuesday 28 May 2013, 12:00-13:00

‘CLL – from chemotherapy to targeted kinase inhibition’

Buffet Lunch will be provided by courtesy of Chugai Pharma UK Ltd.

User Dr George Follows, Consultant Haematologist, Addenbrooke's .

Tuesday 14 May 2013, 12:00-13:00

House Sackler Lecture Theatre (Level 7), Cambridge Institute for Medical Research.

Macrophages Into Tumor Hypoxic Areas: Should I Stay Or Should I Go?

Hutchison/MRC Research Centre Seminar

User Dr Massimiliano Mazzone, VIB Vesalius Research Center, Belgium.

Tuesday 07 May 2013, 12:00-13:00

House CRI Lecture Theatre, Cambridge Research Institute.

“The identification of patients who benefit from targeted therapy in renal cancer”

(The lunch will be provided by courtesy of Pfizer)

User Professor Thomas Powles, Barts Cancer Institute, Queen Mary University of London.

Tuesday 23 April 2013, 12:00-13:00

Computational biology

User Florian Markowetz, Cancer Research UK Cambridge Research Institute.

Thursday 21 March 2013, 09:30-10:30

CANCELLED

User Dr Fiona Blackhall, Manchester University, Manchester Cancer Research Centre Lung Group Lead.

Tuesday 12 March 2013, 12:00-13:00

Epigenetic cancer conspirators: DNA methylation, non-coding RNA and chromatin loops

This is an open seminar, all are welcome to attend

User Adele Murrell, CRUK Cambridge Institute.

Thursday 07 March 2013, 09:45-10:45

Challenges in Implementing Personalized Cancer Medicine: the IGR experience

User Professor Alexander Eggermont, Director General, Institut de Cancérologie Gustave Roussy, France.

Tuesday 19 February 2013, 12:00-13:00

House Sackler Lecture Theatre (Level 7), Cambridge Institute for Medical Research.

Telomeres and the challenges to chromosome integrity

Hutchison/MRC Research Centre Seminar

User Dr Julie Cooper, London Research Institute.

Tuesday 05 February 2013, 12:00-13:00

Proteinases and Cancer

User Gill Murphy, CRUK Cambridge Research Institute.

Thursday 31 January 2013, 09:30-10:30

Stem cells and cancer

User John Stingl, Cambridge Research Institute.

Thursday 24 January 2013, 09:30-10:30

Estrogen receptor and its role in transcription and breast cancer

User Jason Carroll, CRI.

Thursday 17 January 2013, 09:30-10:30

Microtubules: boring polymers or the Achilles heel of cancer?

User Fanni Gergely, CRUK Cambridge Research Institute.

Thursday 13 December 2012, 09:30-10:30

House Sackler Lecture Theatre (Level 7), Cambridge Institute for Medical Research.

Localisation-based feedback controls during mitosis and the maintenance of chromosomal stability

Hutchison/MRC Research Centre Seminar

User Dr Adrian Saurin, University Medical Center Utrecht, The Netherlands.

Tuesday 04 December 2012, 12:00-13:00

Talk postponed Introduction to statistics

**Talk postponed** Will be rescheduled next year

User Sarah Vowler, CRI.

Thursday 29 November 2012, 09:30-10:30

Cellular responses to DNA damage: translating molecular insights towards new cancer therapies

User Prof Steve Jackson, Head of Cancer Research UK Laboratories The Gurdon Institute, Cambridge.

Tuesday 27 November 2012, 12:00-13:00

House CRI Lecture Theatre, Cambridge Research Institute.

Mechanisms of Estrogen Receptor Transcription in Breast Cancer

User Dr Jason Carroll, CRUK Cambridge Research Institute.

Tuesday 20 November 2012, 12:00-13:00

"Towards personalized medicine in Breast Cancer"

User Prof. Dr. Sabine C. Linn, medical oncologist Netherlands Cancer Institute – Antoni van Leeuwenhoek Hospital, Amsterdam, the Netherlands.

Tuesday 13 November 2012, 12:00-13:00

A systems view of the cancer cell: from missing genetic variability to combination therapy

User Andrea Califano, Columbia University.

Wednesday 07 November 2012, 10:30-11:30

A genomic Odyssey of predicting drug response: is Ulysses home yet?

User Dr Federico Innocenti, UNC Institute for Pharmacogenomics and Individualized Therapy.

Tuesday 06 November 2012, 16:00-17:00

House Sackler Lecture Theatre (Level 7), Cambridge Institute for Medical Research.

Signalling Networks in Cell Proliferation and Fate Control

Hutchison/MRC Research Centre Seminar

User Professor Sibylle Mittnacht, UCL Cancer Institute.

Tuesday 06 November 2012, 12:00-13:00

'Circulating Tumour Cells: Biomarker Utility and Insights to Metastasis'

User Professor Caroline Dive, Clinical and Experimental Pharmacology Group, Paterson Institute for Cancer Research, Manchester.

Tuesday 14 August 2012, 12:00-13:00

Understanding Response & Resistance Mechanisms to Targeted Therapy

Note unusual day and time

User Dr Keith Flaherty, Director of Developmental Therapeutics at Massachusetts General Hospital.

Thursday 21 June 2012, 16:00-17:00

House CRI Lecture Theatre, Cambridge Research Institute.

Cancer-related inflammation

User Dr Thorsten Hagemann, Barts Cancer Institute, Queen Mary University of London.

Tuesday 12 June 2012, 12:00-13:00

House CRI Lecture Theatre, Cambridge Research Institute.

Pancreatic cancer: Genetic models to develop novel diagnostic and therapeutic strategies

User Dr Dieter Saur, The Technical University of Munich.

Tuesday 29 May 2012, 12:00-13:00

"Strategies to enhance effectiveness of Radiotherapy in Pancreatic Cancer"

User Dr Thomas Brunner, Gray Institute for Radiation Oncology and Biology, Oxford.

Tuesday 15 May 2012, 12:00-13:00

House Max Perutz Lecture Theatre, MRC LMB.

Investigating key effectors downstream of APC (adenomatous polyposis coli) deletion in vivo

Hutchison/MRC Research Centre Seminar

User Prof Owen Sansom, Beatson Institute, Glasgow.

Tuesday 08 May 2012, 12:00-13:00

ALK Hunting in Colorado - new drugs for lung cancer's new diseases

Note unusual day and time

User Dr Ross Camidge, University of Colorado Hospital (UCH) and the University of Colorado Cancer Center,.

Thursday 03 May 2012, 17:00-18:00

CANCELLED

User Prof Richard Sullivan, Professor, Kings College London, Director, Centre for Global OncoPolicy & Health Kings Health Partners.

Tuesday 24 April 2012, 12:00-13:00

House Sackler Lecture Theatre (Level 7), Cambridge Institute for Medical Research.

Always on guard: p53 dynamics in single living cells

Hutchison/MRC Research Centre Seminar

User Dr Alexander Loewer, Berlin Institute for Medical Systems Biology, Max Delbrueck Center, Germany.

Tuesday 03 April 2012, 12:00-13:00

House Seminar Room 2, Clinical School, Addenbrooke’s.

"Exploiting ASS1 deficiency in the treatment of mesothelioma"

User Dr Peter Szlosarek, Cancer Research UK Clinician Scientist, Senior Lecturer and Honorary Consultant in Medical Oncology, Barts and The London.

Tuesday 27 March 2012, 11:30-13:00

"Thalidomide and its analogues ; How molecules selected for anti-TNFa activity affect so many different pathways with direct binding with Cereblon mediating both anti proliferative and Immunomodulatory functions"

Individuals who are interested in meeting with any of the speakers should contact me asap. Thanks, Jonathan (jlh66@cam.ac.uk)

User Jerome B. Zeldis CEO of Celgene Global Health & Angus Dalgleish, St George's Hospital London.

Tuesday 20 March 2012, 12:00-13:00

Clinical lectures on prostate, bladder, renal and testis cancer

User David Neal, Cancer Research UK Cambridge Research Institute.

Thursday 15 March 2012, 09:30-10:30

House CRI Lecture Theatre, Cambridge Research Institute.

"Re Service Reforms in the new Commissioning Landscape"

User Hannah Farrar, Director of Strategy and System Management, NHS, London.

Tuesday 13 March 2012, 12:00-13:00

"DICER1 and miRNA processing - a novel paradigm in cancer predisposition"

User Dr Marc Tischkowitz, Dept of Medical Genetics, University of Cambridge.

Tuesday 28 February 2012, 12:00-13:00

Functional breast cancer genomics: from basic biology to clinical application

**Talk postponed**

User Carlos Caldas, CRI.

Thursday 23 February 2012, 09:30-10:30

"Myeloproliferative neoplasms – JAK/STAT signalling and stem cell subversion"

User Prof Tony Green, University of Cambridge Department of Haematology.

Tuesday 21 February 2012, 12:00-13:00

Imaging tumour responses to treatment

User Kevin Brindle, Dept. Biochemistry and Cambridge Research Institute.

Thursday 16 February 2012, 09:30-10:30

"Radiotherapy toxicity, Radiogenomics and RAPPER"

User Dr Gill Barnett, Dept. of Oncology.

Tuesday 14 February 2012, 12:00-13:00

House Sackler Lecture Theatre (Level 7), Cambridge Institute for Medical Research.

Transcriptional control of EMT and malignant tumor progression

Hutchison/MRC Research Centre Seminar

User Prof Gerhard Christofori, University of Basel, Switzerland.

Tuesday 07 February 2012, 12:00-13:00

MRI and MRS in cancer research and cancer treatment

User John Griffiths, Cambridge Research Institute.

Thursday 02 February 2012, 09:30-10:30

House Sackler Lecture Theater on level 7 of the CIMR (Cambridge Institute for Medical Research).

“Imaging Biomarkers in Cancer”

User Prof. Fiona Gilbert, Dept. of Radiology.

Tuesday 24 January 2012, 12:00-13:00

Neo-adjuvant radiochemotherapy in breast cancer

User Dr Alain Fourquet, Department of Radiation Oncology, Institut Curie, Paris.

Tuesday 13 December 2011, 12:00-13:00

Integration of Cell Growth and Cell Metabolism by Myc

Hutchison/MRC Research Centre Seminar

User Prof Martin Eilers, Theodor-Boveri-Institute, University of Würzburg, Germany.

Tuesday 06 December 2011, 12:00-13:00

Cancer Therapeutics

User Duncan Jodrell, Cambridge Research Institute and Department of Oncology.

Thursday 01 December 2011, 09:30-10:30

Barrett's oesophagus as a model for early cancer detection/treatment

User Rebecca Fitzgerald, Hutchison/MRC Research Centre.

Thursday 10 November 2011, 09:30-10:30

House Max Perutz Lecture Theatre, MRC LMB.

Cancer Gene Discovery in the Mouse

Hutchison/MRC Research Centre Seminar

User Dr David Adams, Wellcome Trust Sanger Institute.

Tuesday 01 November 2011, 12:00-13:00

‘Genetic predisposition to cancer’

User Prof Bruce Ponder, Cancer Research UK Cambridge Research Institute.

Tuesday 18 October 2011, 12:00-13:00

Tumour-stroma Interactions in Breast Cancer

Hutchison/MRC Research Centre Seminar

User Prof Clare Isacke, Breakthrough Breast Cancer Research Centre, Institute of Cancer Research.

Tuesday 04 October 2011, 12:00-13:00

DNA repair inhibitors in cancer treatment

User Prof Hilary Calvert, UCL Cancer Institute.

Tuesday 20 September 2011, 12:00-13:00

House Max Perutz Lecture Theatre, MRC LMB.

Haploid Genetic Screens in Human Cells

Hutchison/MRC Research Centre Seminar

User Dr Thijn Brummelkamp, Netherlands Cancer Institute.

Tuesday 06 September 2011, 12:00-13:00

The ATM-mediated DNA damage response: moving between the forest and the trees

Hutchison/MRC Research Centre Seminar

User Dr Yossi Shiloh, Tel Aviv University, Israel.

Tuesday 28 June 2011, 12:00-13:00

‘Viral and host contributions to cervical carcinogenesis’

User Dr Nick Coleman, Department of Pathology & Hutchison/MRC Research Centre.

Tuesday 21 June 2011, 12:00-13:00

"Advances in Head and Neck Radiotherapy"

User Dr Chris Nutting, Royal Marsden Hospital.

Tuesday 14 June 2011, 12:00-13:00

"Developing Medicines for Pancreatic Cancer"

User Dr Dave Tuveson, CRUK Cambridge Research Institute.

Tuesday 07 June 2011, 12:00-13:00

SOCCAR trial: an update

User Dr Joe Maguire, Consultant Clinical Oncologist, Clatterbridge Centre for Oncology.

Tuesday 31 May 2011, 12:00-13:00

Genomic Imprinting and Cancer

User Adele Murrell, CRUK Cancer Research Institute.

Thursday 26 May 2011, 09:30-10:30

“What lessons can we learn from transcriptional evolution in cancer research?”

User Dr Duncan Odom, CRUK Cambridge Research Institute.

Tuesday 24 May 2011, 12:00-13:00

CANCELLED

User Prof. Roy Rampling, University of Glasgow and The Beatson Cancer Centre, Glasgow.

Tuesday 17 May 2011, 12:00-13:00

"Multi-site post-translational modification as a quantitative regulator of transcriptional output during neurogenesis"

User Dr Anna Philpott, Department of Oncology, MRC-Hutchison Research Centre.

Tuesday 10 May 2011, 12:00-13:00

CANCELLED

Hutchison/MRC Research Centre Seminar

User Prof Sibylle Mittnacht, The Institute of Cancer Research.

Tuesday 03 May 2011, 12:00-13:00

CANCELLED

User Dr Vincent Gnanapragasam, Hutchison/MRC Research Centre & Addenbrooke's Hospital.

Tuesday 26 April 2011, 12:00-13:00

Signal transduction and membrane trafficking

User Ian Mills, CRUK Cambridge Research Institute.

Thursday 14 April 2011, 09:30-10:30

"Somatic Genetics of Human Cancer - Moving Towards Large Scale Resequencing of Cancer Genomes"

User Dr Andy Futreal, The Wellcome Trust Sanger Institute, Hinxton.

Tuesday 12 April 2011, 12:00-13:00

"The Cambridge breast cancer program- recent progress"

User Dr Carlos Caldas, CRUK Cambridge Research Institute.

Tuesday 15 March 2011, 12:00-13:00

"FGF-2, S6 Kinase 2 and Chemo-resistance in Lung Cancer"

User Prof. Michael Seckl, Imperial College, London and Charing Cross Hospital.

Tuesday 08 March 2011, 12:00-13:00

Mesothelioma: a disease of our time

User Dr David Gilligan, Addenbrooke's Hospital.

Tuesday 22 February 2011, 12:00-13:00

"Targetting pre-neoplasia in the bronchus"

User Dr Robert Rintoul, Papworth Hospital.

Tuesday 15 February 2011, 12:00-13:00

Application of Systems Biology Approaches to Study Cell Signalling and Transcription

Hutchison/MRC Research Centre Seminar

User Prof Mike White, University of Liverpool.

Tuesday 01 February 2011, 12:00-13:00

Control of DNA Replication

User Ron Laskey, MRC Cancer Cell Unit, MRC-Hutchison Research Centre.

Thursday 27 January 2011, 09:30-10:30

"Leukaemia stem cells: how normal stem cell function is subverted in haematological malignancies"

User Dr Brian Huntly, Department of Haematology.

Tuesday 25 January 2011, 12:00-13:00

Systems approaches to understanding transcriptional regulation

User Duncan Odom, CRUK Cambridge Research Institute.

Thursday 20 January 2011, 09:30-10:30

“Breast MRI by the Shutter-Speed Method: Elimination of Unnecessary Breast Biopsies"

User Dr Charles S. Springer, Jr., Advanced Imaging Research Centre. Oregon Health & Science University.

Tuesday 21 December 2010, 12:00-13:00

RCC Cinderella comes of age

User Prof. Tim Eisen, Dept. of Oncology, University of Cambridge & Addenbrooke's Hospital.

Tuesday 14 December 2010, 12:00-13:00

Neuroblastoma- Disordered Developmental Programs Contribute to Tumorigenesis

Hutchison/MRC Research Centre Seminar- Please note change to regular time and date

User Prof Carol Thiele, National Cancer Institute, USA.

Thursday 02 December 2010, 14:30-15:30

"Susceptibility to Cancer - What's New?"

User Prof Doug Easton, Strangeways Research Laboratory.

Tuesday 30 November 2010, 12:00-13:00

Tumour suppressors mechanisms and cellular senescence

User Masashi Narita, CRUK Cambridge Research Institute.

Thursday 25 November 2010, 09:30-10:30

Targeting NG2 Cells in Glioblastoma

User Dr Colin Watts, Cambridge Centre for Brain Repair.

Tuesday 23 November 2010, 12:00-13:00

Oncogenes and Tumour Suppressors 1 & 2

Note extended session - finish time 11 am

User Ashok Venkitaraman & Dave Tuveson; Hutchison/MRC Research Centre & Cambridge Research Institute.

Thursday 18 November 2010, 09:30-11:00

"Chromosome Translocations and Tumour Suppressors in Breast Cancer"

User Dr Paul Edwards, Hutchison/MRC Research Centre.

Tuesday 26 October 2010, 12:00-13:00

"Brain Metastases – a cross cutting theme: Review of the Brain Metastasis Service and Future Research Potential"

User Dr Sarah Jefferies, Addenbrooke's Hospital.

Tuesday 19 October 2010, 12:00-13:00

"Imaging Tumour Cell Death"

User Prof. Kevin Brindle, CRUK Cambridge Research Institute.

Tuesday 12 October 2010, 12:00-13:00

“EGFR Mutation Screening in NSCLC”

User Dr David Gonzalez de Castro, The Institute of Cancer Research and Royal Marsden Hospital.

Tuesday 28 September 2010, 12:00-13:00

Pathway Analysis of Glioblastoma Tissue After Preoperative Treatment with the EGFR Tyrosine Kinase Inhibitor Gefitinib – A Phase “0 Trial”

User Dr Monika Hegi, University Hospital (CHUV), Lausanne, Switzerland.

Tuesday 21 September 2010, 12:00-13:00

Interactions of Epidermal Growth Factor Receptor Inhibition with DNA damage in the treatment of gastrointestinal cancer

User Prof Daniel Hochhauser, University College London.

Tuesday 14 September 2010, 12:00-13:00

Unravelling cancer cell signalling networks and screening for novel drug targets

Hutchison/MRC Research Centre Seminar

User Daniel Peeper, The Netherlands Cancer Institute.

Tuesday 07 September 2010, 12:00-13:00

"Breast Radiotherapy - Past, Present and Future"

User Dr Charlotte Coles, Addenbrooke's Hospital.

Tuesday 29 June 2010, 12:00-13:00

"Gastro Intestinal Stroma Tumours (GISTS)"

User Dr Ramesh Bulusu, Addenbrooke's Hospital.

Tuesday 22 June 2010, 12:00-13:00

Dynamic Notch signaling in neural progenitor cells

Hutchison/MRC Research Centre Seminar

User Ryoichiro Kageyama, Kyoto University, Japan.

Tuesday 15 June 2010, 12:00-13:00

New approaches to the clinical management of cervical cancer

User Nick Coleman, MRC Cancer Cell Unit, Hutchison-MRC Research Centre.

Thursday 10 June 2010, 09:30-10:30

"A New Window of Opportunity in Prostate Cancer"

User Dr Danish Mazhar, Addenbrooke's Hospital.

Tuesday 25 May 2010, 12:00-13:00

Talk Cancelled

Cancelled due to unforseen circumstances, apologies for the inconvenience

User Guillermo de la Cueva Mendez, Hutchison/MRC Research Centre Cancer Cell Unit..

Thursday 20 May 2010, 09:30-10:30

"Stem cell identity and mRNA export: unexpected roles of geminin and GANP"

User Prof. Ron Laskey, Hutchison/MRC Research Centre.

Tuesday 18 May 2010, 12:00-13:00

"Cellular Senescence as a Tumour Suppressor Mechanism, Particular Focus will be on the Autophagy/mTOR Pathway"

User Dr Masashi Narita, CRUK Cambridge Research Institute.

Tuesday 11 May 2010, 12:00-13:00

Mechanisms regulating neural differentiation

Hutchison/MRC Research Centre Seminar

User Kate Storey, University of Dundee.

Tuesday 04 May 2010, 12:00-13:00

Radiotherapy in the management of cancer

User Neil Burnet, Department of Oncology and Addenbrooke's Hospital.

Thursday 29 April 2010, 09:30-10:30

“Macromolecular interactions in the control of chromosome instability”

User Prof. Ashok Venkitaramann, (Hutchison-MRC Research Centre).

Tuesday 27 April 2010, 12:00-13:00

Stem cell fate

User Phil Jones, MRC Cancer Cell Unit, Hutchison-MRC Research centre.

Thursday 22 April 2010, 09:30-10:30

The NCAG Report: Delivering a World Class Chemotherapy Service

User Prof Roger James, Previously: • Deputy Medical Director Maidstone and Tunbridge Wells NHS Trust • Medical Director Kent & Medway Cancer Network.

Tuesday 20 April 2010, 12:00-13:00

CANCELLED

User Dr James Brenton, CRUK Cambridge Research Institute.

Tuesday 13 April 2010, 12:00-13:00

"Non-Invasive Diagnosis of Brain Cancer"

User Prof. John Griffiths, CRUK Cambridge Research Institute.

Tuesday 30 March 2010, 12:00-13:00

Deciphering the Mammary Epithelial Cell Hierarchy

User Dr John Stingl, CRUK Cambridge Research Institute.

Tuesday 16 March 2010, 12:00-13:00

"The Fine Scale Mapping of Breast Cancer Loci found via GWAS - searching for the Causative Variants"

User Dr Alison Dunning, Strangeways Research Laboratory.

Tuesday 09 March 2010, 12:00-13:00

The Role of the Receptor Tyrosine Kinase Antagonist, Lrig1, in Normal Tissue Homeostasis and Cancer

Hutchison/MRC Research Centre Seminar

User Kim Jensen, Anne McLaren Laboratory for Regenerative Medicine and Department of Oncology.

Tuesday 02 March 2010, 12:00-13:00

CANCELLED

User Dr Alison Dunning, Strangeways Research Laboratory & Dept. of Oncology.

Tuesday 23 February 2010, 12:00-13:00

The prognostic significance of subtypes of breast cancer classified using immunohistochemistry

User Dr Paul Pharoah, Strangeways Research Laboratory/Oncology.

Tuesday 16 February 2010, 12:00-13:00

Why computational biology is useful in the cancer world

User Simon Tavaré, CRUK Cambridge Research Institute.

Thursday 11 February 2010, 09:30-10:30

High-throughput Cancer Cell line Screens: Linking Drug Response to Molecular Signatures

User Dr Ultan McDermott, Cancer Genome Project, Wellcome Trust Sanger Institute.

Tuesday 09 February 2010, 12:00-13:00

Can we age in utero? Can we kill cancer cells by making them replicate faster? And other ATR stories…

Hutchison/MRC Research Centre Seminar

User Oscar Fernandez-Capetillo, Spanish National Cancer Research Centre (CNIO).

Tuesday 02 February 2010, 12:00-13:00

HPV vaccines - will they do their job?

User Prof. Margaret Stanley, Dept. of Pathology, University of Cambridge.

Tuesday 26 January 2010, 12:00-13:00

Investigating the interaction of Radiotherapy & Temozolomidefor Glioblastoma

User Dr Raj Jena, Addenbrooke's Hospital.

Tuesday 19 January 2010, 12:00-13:00

PREDICT: A NEW UK PROGNOSTIC MODE THAT PREDICTS SURVIVAL FOLLOWING SURGERY FOR INVASIVE BREAST CANCER (GC Wishart, EM Azzato, PDP Pharoah, DC Greenberg, J Rashbass, O Kearins, G Lawrence, C Caldas C, PM Ravdin)

User Prof. Gordon Wishart, Addenbrooke's Hospital.

Tuesday 12 January 2010, 12:00-13:00

The new LAW of microRNA-mediated gene silencing: implications for lung cancer development

User Dr Tyson V. Sharp, School of Biomedical Sciences, University of Nottingham.

Tuesday 15 December 2009, 12:00-13:00

Cellular senescence: molecular mechanisms and implications for cancer and aging

Hutchison/MRC Research Centre Seminar

User Peter Adams, Beatson Institute for Cancer Research, Glasgow.

Tuesday 01 December 2009, 12:00-13:00

Cell Signalling

User Ermanno Gherardi, MRC Laboratory of Molecular Biology.

Thursday 26 November 2009, 09:30-10:30

“Intensity modulated radiotherapy for children’s tumours and estimation of the carcinogenic risk”

User Dr Michael Williams & Dr Gail Horan, Addenbrooke's Hospital.

Tuesday 24 November 2009, 12:00-13:00

"The Arguments for and against Sentinel Node Biopsy (SNB) in Melanoma"

User Prof. J Meirion Thomas, Royal Marsden Hospital & Imperial College, London.

Tuesday 17 November 2009, 12:00-13:00

The irreversibility of cell cycle transitions: why the clock never turns back

Hutchison/MRC Research Centre Seminar

User Frank Uhlmann, CRUK London Research Institute.

Tuesday 03 November 2009, 12:00-13:00

Steroid Hormone Receptors in Prostate Cancer: A Hard Habit to Break?

User Dr Gerhardt Attard, The Institute of Cancer Research and the Royal Marsden Hospital.

Tuesday 27 October 2009, 12:00-13:00

"Phospholipase and lysophospholipase D signalling in cancer"

User Prof. Michael Wakelam, Institute Director, The Babraham Institute.

Tuesday 20 October 2009, 12:00-13:00

"Immunostimulatory antibodies in cancer treatment"

User Prof. Peter Johnson, Professor of Medical Oncology, University of Southampton.

Tuesday 13 October 2009, 12:00-13:00

Molecular Mechanisms of Cellular Senescence in Cancer and Ageing

Hutchison/MRC Research Centre Seminar

User Fabrizio d'Adda di Fagagna, IFORM-IEO, Milan.

Tuesday 29 September 2009, 12:00-13:00

Clinical Aspects of Proton Radiotherapy

User Prof Tony Lomax, Head of Medical Physics, Centre for Proton Radiation Therapy, Paul Scherrer Institute, Switzerland.

Tuesday 15 September 2009, 12:00-13:00

Adoptive T Cell Therapy of Cancer

User Cassian Yee, Fred Hutchinson Research Center, Seattle.

Tuesday 08 September 2009, 12:00-13:00

Prospective translational research in clinical trials

User Helena Earl, Department of Oncology.

Thursday 02 July 2009, 09:30-10:30

Genome scans in breast and prostate cancer - what have we learned & where next?

User Doug Easton, Strangeways Research Laboratory.

Tuesday 30 June 2009, 12:00-13:00

House Cancer Research UK Cambridge Research Institute, Lecture Theatre.

Germ Cell Tumours (GCTs) of Young People: Clinical and Biological Approaches

User James Nicholson and Matthew Murray, Paediatrics, Addenbrooke's Hospital.

Tuesday 23 June 2009, 12:00-13:00

House Cancer Research UK Cambridge Research Institute, Lecture Theatre.

Is brain cancer a stem cell disease?

User Colin Watts, Department of Clinical Neurosciences.

Tuesday 16 June 2009, 12:00-13:00

House Cancer Research UK Cambridge Research Institute, Lecture Theatre.

Translational imaging studies in ovarian cancer

User James Brenton, CRUK Cambridge Research Institute and Evis Sala, Department of Radiology.

Tuesday 09 June 2009, 12:00-13:00

A model for all genomes: the role of RNA polymerases fixed in factories

User Peter Cook, University of Oxford.

Tuesday 02 June 2009, 12:00-13:00

House Cancer Research UK Cambridge Research Institute, Lecture Theatre.

Using genetics to personalize melanoma therapy

User Keiran Smalley, Moffitt Cancer Center.

Tuesday 26 May 2009, 12:00-13:00

House Cancer Research UK Cambridge Research Institute, Lecture Theatre.

Common germline variation and colorectal cancer

User Richard Hubner, Royal Marsden Hospital.

Tuesday 19 May 2009, 12:00-13:00

Inherited susceptibility to cancer

User Bruce Ponder, CRUK Cambridge Research Institute.

Thursday 14 May 2009, 09:30-10:30

Assessing responses to cancer therapy using molecular imaging magnetic resonance methods

User Kevin Brindle and John Griffiths, CRUK Cambridge Research Institute.

Thursday 07 May 2009, 09:30-10:30

Taming the tiger by the tail: modulation of DNA damage responses by telomeres

User David Lydall, Institute for Ageing and Health, Newcastle University.

Tuesday 05 May 2009, 12:00-13:00

OPCML in Tumour Gene Therapy in Ovarian Cancer

User Hani Gabra, Faculty of Medicine, Imperial College London.

Tuesday 28 April 2009, 12:00-13:00

Stem cells and cancer (epithelial cancers)

User Fiona Watt, CRUK Cambridge Research Institute.

Thursday 23 April 2009, 09:30-10:30

Preservation of fertility in patients with cancer

User Raj Mathur (Addenbrooke's Hospital) and Tom Mathews (Medical Director, Bourn Hall).

Tuesday 21 April 2009, 12:00-13:00

Connecting Lung Epithelial Stem Cells and Lung Cancer by Stress-Activated Protein Kinases

User Juan Jose Ventura, Wellcome Trust Centre for Stem Cell Research, University of Cambridge.

Tuesday 07 April 2009, 12:00-13:00

Analysis of early events after DNA damage in living cells; the HP1 paradigm

User Anand Jeyasekharan, Hutchison/MRC Research Centre.

Tuesday 31 March 2009, 12:00-13:00

What comes after cancer stem cells?

User Doug Winton, CRUK Cambridge Research Institute.

Tuesday 24 March 2009, 12:00-13:00

Outreach chemotherapy programme

User Pippa Corrie, Addenbrooke's Hospital.

Tuesday 17 March 2009, 12:00-13:00

Intestinal cancer models and stem cell biology

User Doug Winton, CRUK Cambridge Research Institute.

Thursday 12 March 2009, 09:30-10:30

Radiation-induced bowel damage: let's put right what is wrong

User Jervoise Andreyev, Royal Marsden Hospital.

Tuesday 10 March 2009, 12:00-13:00

The spatial organisation of Ras signaling

User Philippe Bastiaens, Max Planck Institute of Molecular Physiology, Germany.

Tuesday 03 March 2009, 12:00-13:00

Genetic association studies to find common disease susceptibility alleles

User Alison Dunning, Strangeways Research Laboratories.

Thursday 26 February 2009, 09:30-10:30

House Cancer Research UK Cambridge Research Institute, Lecture Theatre.

The role of cyclin-kinase inhibitors in the development of cancer

User Nisar Malek, Hannover Medical School, Germany.

Tuesday 24 February 2009, 12:00-13:00

Clinical potential of functional ion channel expression in cancer

User Mustafa Djamgoz, Imperial College London.

Tuesday 10 February 2009, 12:00-13:00

Role of the c-Myc-target gene Misu (NSun2) in regulating epidermal stem cell fate and its implications for cancer

User Michaela Frye, Wellcome Trust Centre for Stem Cell Research, University of Cambridge.

Tuesday 03 February 2009, 12:00-13:00

House Cancer Research UK Cambridge Research Institute, Lecture Theatre.

Sarcomas and the insulin-like growth factor pathway

User Robert Maki, Memorial Sloan-Kettering Research Center.

Tuesday 27 January 2009, 12:00-13:00

House Cancer Research UK Cambridge Research Institute, Lecture Theatre.

The evidence for lifestyle after cancer to reduce relapse and survival

User Robert Thomas, Addenbrooke's Hospital.

Tuesday 20 January 2009, 12:00-13:00

Patterns of stem and progenitor cell fate in adult tissues

User Professor Ben Simons, Department of Physics, Cambridge University.

Tuesday 06 January 2009, 12:00-13:00

House Alice Fisher Lecture Theatre, S Block, Addenbrooke's Site.

Title to be confirmed

This talk has now been postponed until next year

User Rebecca Fitzgerald, Cancer Cell Unit, Hutchison/MRC Research Laboratory.

Tuesday 09 December 2008, 12:00-13:00

House Room 009, Cancer Research UK Cambridge Research Institute.

Tumour suppressors 1 and 2

User Ashok Venkitaraman & Dave Tuveson; Hutchison/MRC Research Centre & Cambridge Research Institute.

Wednesday 03 December 2008, 09:30-10:30

Delineating the Fanconi Anaemia DNA repair defect

User KJ Patel, MRC Laboratory of Molecular Biology.

Tuesday 02 December 2008, 12:00-13:00

House Alice Fisher Lecture Theatre, S Block, Addenbrooke's Site.

The role of developmental biology in cancer research

User Anna Philpott and Shin-ichi Ohnuma, Department of Oncology, MRC-Hutchison Research Centre.

Tuesday 25 November 2008, 12:00-13:00

House Alice Fisher Lecture Theatre, S Block, Addenbrooke's Site.

Colorectal neoplasia: what we know and don't know about genes and environment

User John Potter, Fred Hutchinson Cancer Research Centre.

Tuesday 18 November 2008, 12:00-13:00

House Cancer Research UK Cambridge Research Institute, Lecture Theatre.

The Editorial Process Demystified

Note unusual time and venue

User Andrew Sugden, International Managing Editor, Science Magazine.

Thursday 13 November 2008, 13:00-14:00

House Alice Fisher Lecture Theatre, S Block, Addenbrooke's Site.

The West Anglia CLRN, TCRNs and the Coordinated System for gaining NHS Permission – How is it all going to work?

User Lena Pettersson, Lead RM and G Manager, West Anglia NIHR CLRN.

Tuesday 11 November 2008, 12:00-13:00

Mechanisms of DNA replication

User Nick Robinson, MRC Cancer Cell Unit, Hutchison/MRC Centre.

Thursday 06 November 2008, 09:30-10:30

House Alice Fisher Lecture Theatre, S Block, Addenbrooke's Site.

The role of Fam38 in integrin activation and lung cancer

User Tariq Sethi, Chair of Respiratory and Lung Cancer Biology, Centre for Inflammation Research, University of Edinburgh.

Tuesday 28 October 2008, 12:00-13:00

House Alice Fisher Lecture Theatre, S Block, Addenbrooke's Site.

High-throughput cancer cell line screening: a tool for discovery

User Ultan McDermott, Massachusetts General Hospital Cancer Center and Harvard Medical School.

Tuesday 14 October 2008, 12:00-13:00

House Alice Fisher Lecture Theatre, S Block, Addenbrooke's Site.

Title to be confirmed

User Richard Benson, Addenbrooke's Hospital.

Tuesday 30 September 2008, 12:00-13:00

House Alice Fisher Lecture Theatre, S Block, Addenbrooke's Site.

Title to be confirmed

User Nick Carroll, Department of Radiology.

Tuesday 23 September 2008, 12:00-13:00

House Alice Fisher Lecture Theatre, S Block, Addenbrooke's Site.

Early phase clinical trials in Cambridge

User Duncan Jodrell, Cambridge Research Institute and Department of Oncology.

Tuesday 16 September 2008, 12:00-13:00

Special seminar: Analysing the dynamic glycome

Please note that this lecture is on a Wednesday at the CRI.

User Lara Mahal, University of Texas, Austin.

Wednesday 03 September 2008, 12:00-13:00

House The Sackler Lecture Theatre, Level 7, Wellcome Trust/MRC Building, Addenbrooke's Site.

Chromatin modifying enzymes: their function and role in cancer

User Tony Kouzarides, WT/CRUK Gurdon Institute.

Tuesday 02 September 2008, 12:00-13:00

House Alice Fisher Lecture Theatre, S Block, Addenbrooke's Site.

TBC

User Gill Murphy, CRI and Charles Wilson, Addenbrooke's Hospital.

Tuesday 24 June 2008, 12:00-13:00

House Alice Fisher Lecture Theatre, S Block, Addenbrooke's Site.

Using Bayesian analysis in randomised phase II clinical trials to determine the worth of proceeding to phase III

User Cindy Billingham, University of Birmingham.

Tuesday 17 June 2008, 12:00-13:00

House Alice Fisher Lecture Theatre, S Block, Addenbrooke's Site.

'Mechanisms of tamoxifen action and resistance' and 'Cambridge Oncology - Past, Present & Future: A tour from the 18th to 21st Century'

User Jason Carroll, CRI and David Gilligan, Addenbrooke's Hospital.

Tuesday 10 June 2008, 12:00-13:00

Taming Glioblastoma -Targeting Angiogenesis (CRI Special Seminar)

User Dr Steve Brem, Moffitt Cancer Center.

Monday 09 June 2008, 13:00-14:00

House Alice Fisher Lecture Theatre, S Block, Addenbrooke's Site.

Trials and Tribulations in the Management of Head and Neck Cancer

User Sarah Jefferies, Addenbrooke's Hospital.

Tuesday 27 May 2008, 12:00-13:00

House Alice Fisher Lecture Theatre, S Block, Addenbrooke's Site.

TBC

User Phil Jones, MRC Cancer Cell Unit, Hutchison-MRC Research Centre and Kate Fife, Addenbrooke's Hospital.

Tuesday 20 May 2008, 12:00-13:00

House Alice Fisher Lecture Theatre, S Block, Addenbrooke's Site.

TBC

User Adele Murrell, CRUK Cancer Research Institute and TBC.

Tuesday 13 May 2008, 12:00-13:00

Targeting Hyperactive Ras and Uncovering Mechanisms of Therapeutic Resistance in Genetically Engineered Mice

User Kevin Shannon, University of California San Francisco.

Tuesday 29 April 2008, 12:00-13:00

House Alice Fisher Lecture Theatre, S Block, Addenbrooke's Site.

Chromosome translocations and gene fusions in breast cancer and Improving outcomes in melanoma: a fresh look

User Paul Edwards (Hutchison/MRC Research Centre) and Pippa Corrie (Addenbrooke's Hosptial, Clinical Oncologist, Lung and Upper GI Cancer).

Tuesday 22 April 2008, 12:00-13:00

House Alice Fisher Lecture Theatre, S Block, Addenbrooke's Site.

Title to be confirmed

User Hugo Ford, Addenbrooke's Hospital.

Tuesday 15 April 2008, 12:00-13:00

House Alice Fisher Lecture Theatre, S Block, Addenbrooke's Site.

Breast Cancer Heterogeneity and the Cancer Stem Cell Hypothesis

User John Stingl, Cambridge Research Institute.

Tuesday 08 April 2008, 12:00-12:30

House Alice Fisher Lecture Theatre, S Block, Addenbrooke's Site.

Title to be confirmed

User Ermanno Gherardi (MRC Laboratory of Molecular Biology) and Helena Earl (Medical Oncologist; Sarcoma, breast and ovarian cancer), Addenbrooke's Hospital).

Tuesday 25 March 2008, 12:00-13:00

House Alice Fisher Lecture Theatre, S Block, Addenbrooke's Site.

'Monitoring anticancer drug uptake by magnetic imaging and spectroscopy' and 'Breast cancer heterogeneity- a clinical challenge'

User John Griffiths (CRUK Cambridge Research Institute) and Carlos Caldas (CRUK Cambridge Research Institute).

Tuesday 18 March 2008, 12:00-13:00

House Alice Fisher Lecture Theatre, S Block, Addenbrooke's Site.

Title to be confirmed

User Paul Pharoah (Strangeways Research Laboratories) and Rajesh Jena (Addenbrooke's Hospital)).

Tuesday 11 March 2008, 12:00-13:00

House Alice Fisher Lecture Theatre, S Block, Addenbrooke's Site.

Experimental manipulation of the epidermis to study normal and cancer stem cells and The GIST of GISTS (Gastrointestinal Stromal tumours)

User Fiona Watt, CRUK Cambridge Research Institute and Ramesh Bulusu, Clinical Oncologist (Lung/Upper GI/Lymphoma), Addenbrooke's Hospital.

Tuesday 26 February 2008, 12:00-13:00

House Alice Fisher Lecture Theatre, S Block, Addenbrooke's Site.

Title to be confirmed

User Stefanie Reichelt (CR UK Cambridge Research Institute) and Sara Booth (Palliative Care), Addenbrooke's Hospital.

Tuesday 19 February 2008, 12:00-13:00

House Alice Fisher Lecture Theatre, S Block, Addenbrooke's Site.

Imaging biology in the cancer patient (K. Brindle)

User Kevin Brindle (CRUK Cambridge Research Institute and Department of Biochemistry) and Athar Ahmad (Medical Oncologist, Colorectal Tumours), Addenbrooke's Hospital.

Tuesday 12 February 2008, 12:00-13:00

Ubiquitin / proteasome mediated protein degradation

User Laura Itzhaki, MRC Cancer Cell Unit, MRC-Hutchison Research Centre.

Thursday 31 January 2008, 09:30-10:30

House Alice Fisher Lecture Theatre, S Block, Addenbrooke's Site.

"Computational biology and cancer: the CRI perspective" and "Lung Cancer: A New Strategy"

User Simon Tavaré, CRUK Cambridge Research Institute and Tim Eisen, Medical Oncologist (Lung and Renal cancer), Addenbrooke's Hospital.

Tuesday 29 January 2008, 12:00-13:00

House Alice Fisher Lecture Theatre, S Block, Addenbrooke's Site.

Acute Myeloid Leukaemia: Molecular Pathogenesis, Prognostication and Targeted therapy (Brian Huntly)

User Brian Huntly (Department of Haematology, Cambridge Institute of Medical Research) & Charles Crawley (Oncology Department, Addenbrookes Hospital).

Tuesday 22 January 2008, 12:00-13:00

Beyond VEGF: vascular signaling targets for therapeutic manipulation

User David Quinn, University of Southern California.

Tuesday 18 December 2007, 12:00-13:00

House The Sackler Lecture Theatre, Level 7, Wellcome Trust/MRC Building, Addenbrooke's Site.

Searching for and confirming common breast cancer risk alleles (Dunning) Update on Diet and Breast Cancer (Bingham)

User Alison Dunning & Sheila Bingham, Department of Oncology & MRC Dunn Human Nutrition Unit.

Tuesday 04 December 2007, 12:00-13:00

House The Sackler Lecture Theatre, Level 7, Wellcome Trust/MRC Building, Addenbrooke's Site.

Progress in prostate cancer and the androgen receptor

User David Neal and Ian Mills, CRUK Cambridge Research Institute.

Tuesday 27 November 2007, 12:00-13:00

House The Sackler Lecture Theatre, Level 7, Wellcome Trust/MRC Building, Addenbrooke's Site.

Title to be confirmed

User Margaret Stanley, Department of Pathology.

Tuesday 20 November 2007, 12:00-13:00

House The Sackler Lecture Theatre, Level 7, Wellcome Trust/MRC Building, Addenbrooke's Site.

"High throughput mapping of cis-regulatory DNA elements: From genomic arrays to functional biology" (George Follows) & "Rapid evolutionary turnover of transcription factor binding" (Duncan Odom)

User George Follows (Cambridge Institute for Medical Research) and Duncan Odom (CRUK Cambridge Research Institute).

Tuesday 13 November 2007, 12:00-13:00

House The Sackler Lecture Theatre, Level 7, Wellcome Trust/MRC Building, Addenbrooke's Site.

Gain-of-function JAK2 mutations in the human myeloproliferative disorders

User Linda Scott (Cambridge Institute for Medical Research).

Tuesday 23 October 2007, 12:00-13:00

House The Sackler Lecture Theatre, Level 7, Wellcome Trust/MRC Building, Addenbrooke's Site.

Proteins that license DNA replication (Laskey) Clinical exploitation of proteins that license DNA replication (Coleman)

User Ron Laskey and Nick Coleman (Hutchison-MRC Research Centre).

Tuesday 09 October 2007, 12:00-13:00

House The Sackler Lecture Theatre, Level 7, Wellcome Trust/MRC Building, Addenbrooke's Site.

Title to be confirmed

User David Baulcombe, Sainsbury Lab, Norwich.

Tuesday 18 September 2007, 12:00-13:00

House The Sackler Lecture Theatre, Level 7, Wellcome Trust/MRC Building, Addenbrooke's Site.

Molecular genetics of MALT lymphoma: application in diagnosis and prognosis (Prof Ming Du), tbc (Prof Robert Marcus)

User Robert Marcus (Addenbrooke's Hospital) and Ming Du (University of Cambridge Department of Pathology).

Tuesday 11 September 2007, 12:00-13:00

House The Sackler Lecture Theatre, Level 7, Wellcome Trust/MRC Building, Addenbrooke's Site.

"Targeting the Met receptor for cancer therapy" (Ermanno Gherardi) and "Preclinical efforts in Pancreatic Cancer" (Dave Tuveson)

User Ermanno Gherardi (MRC Laboratory of Molecular Biology) and Dave Tuveson (CRUK Cambridge Research Institute).

Tuesday 04 September 2007, 12:00-13:00

House The Sackler Lecture Theatre, Level 7, Wellcome Trust/MRC Building, Addenbrooke's Site.

Targeting RET kinase activity as a novel therapeutic strategy for medullary thyroid carcinoma

User Francesca Carlomagno, University of Naples.

Tuesday 17 July 2007, 12:00-13:00

Introduction to chemotherapy: role of Kaplan Meier curves in clinical cancer research

User Luke Hughes-Davies, Department of Oncology.

Wednesday 04 July 2007, 09:30-10:30

Chromatin modifying enzymes and their involvement in cancer

User Luke Hughes-Davies, Department of Oncology.

Wednesday 27 June 2007, 09:30-10:30

House The Sackler Lecture Theatre, Level 7, Wellcome Trust/MRC Building, Addenbrooke's Site.

Developments in radiotherapy: new treatments for today and tomorrow

User Neil Burnet, Deptartment of Oncology.

Tuesday 26 June 2007, 12:00-13:00

House The Sackler Lecture Theatre, Level 7, Wellcome Trust/MRC Building, Addenbrooke's Site.

Exploiting senescence and anoikis in function-based oncogenomic screens

Host: Ashok Venkitaraman

User Daniel Peeper, Netherlands Cancer Institute.

Tuesday 19 June 2007, 12:00-13:00

A tool of developmental biology for understanding tumorigenesis

User Shin-ichi Ohnuma, Hutchison/MRC Research Centre, Dept of Oncology..

Wednesday 13 June 2007, 09:30-10:30

House The Sackler Lecture Theatre, Level 7, Wellcome Trust/MRC Building, Addenbrooke's Site.

Towards a fuller understanding of inherited susceptibility to colorectal cancer

User Richard Houlston, Institute of Cancer Research, Sutton.

Tuesday 12 June 2007, 12:00-13:00

House The Sackler Lecture Theatre, Level 7, Wellcome Trust/MRC Building, Addenbrooke's Site.

Novel mechanisms of clinical drug resistance in ovarian cancer

User James Brenton, CRUK Cambridge Research Institute.

Tuesday 05 June 2007, 12:00-13:00

House The Sackler Lecture Theatre, Level 7, Wellcome Trust/MRC Building, Addenbrooke's Site.

Molecular heterogeneity of breast cancer - biological and clinical implications

User Carlos Caldas, CRUK Cambridge Research Institute.

Tuesday 29 May 2007, 12:00-13:00

House The Sackler Lecture Theatre, Level 7, Wellcome Trust/MRC Building, Addenbrooke's Site.

Experimental cancer medicine at the Dana Farber Cancer Institute

User Lee Nadler, Dana Farber Cancer Institute, Boston, USA.

Tuesday 15 May 2007, 12:00-13:00

House The Sackler Lecture Theatre, Level 7, Wellcome Trust/MRC Building, Addenbrooke's Site.

Germline genetic predictors of prognosis in breast cancer

User Paul Pharoah, Department of Oncology, Strangeways Research Laboratories.

Tuesday 08 May 2007, 12:00-13:00

House The Sackler Lecture Theatre, Level 7, Wellcome Trust/MRC Building, Addenbrooke's Site.

Dimethyl sulfoxide to vorinostat-targeted histone deacetylase inhibitor – mechanisms of action as an anti-cancer drug

User Paul Marks, Sloan-Kettering Institute, New York.

Tuesday 01 May 2007, 12:00-13:00

House The Sackler Lecture Theatre, Level 7, Wellcome Trust/MRC Building, Addenbrooke's Site.

RNAi Functional Analysis of Drug Resistance Pathways

User Charlie Swanton, Cancer Research UK London Research Institute.

Tuesday 24 April 2007, 12:00-13:00