The role of Fam38 in integrin activation and lung cancer

Add to your list(s) Download to your calendar using vCal

• Tariq Sethi, Chair of Respiratory and Lung Cancer Biology, Centre for Inflammation Research, University of Edinburgh
• Tuesday 28 October 2008, 12:00-13:00
• Alice Fisher Lecture Theatre, S Block, Addenbrooke's Site.

If you have a question about this talk, please contact Laura Blackburn.

I will describe the cloning and characterisation of a previously uncharacterised endoplasmic reticulum bound protein Fam38, which is downregulated in lung cancer cell lines and downregulation transforms bronchial epithelial cells. Fam38 activates integrins via R-Ras, mediating calcium mobilisation and calpain activation demonstrating a novel pathway for integrin activation via the ER.

This talk is part of the Cambridge Oncology Seminar Series series.

This talk is included in these lists:

• Alice Fisher Lecture Theatre, S Block, Addenbrooke's Site
• All Talks (aka the CURE list)
• Biology
• CCC talks for website
• CRUK CI Seminars
• Cambridge Oncology Seminar Series
• Life Sciences
• Life Sciences
• ME Seminar
• MRC Cancer Unit Seminars
• PMRFPS's
• cancer
• cri
• my_list
• other talks
• se393's list
• sfm36

Note that ex-directory lists are not shown.