A systems view of the cancer cell: from missing genetic variability to combination therapy

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• Andrea Califano, Columbia University
• Wednesday 07 November 2012, 10:30-11:30
• CRI Lecture Theatre.

If you have a question about this talk, please contact Laura Blackburn.

Dr Califano’s lab have been leaders in the development of biochemically validated genomewide maps of transcriptional and post-transcriptional interaction in several human cell contexts, including different cancer types and normal and tumour-related stem cells. The Califano lab integrates the development of analytical methodologies with high-throughput experimental assays for data generation and biological/biochemical validation. In particular, the lab have developed the “master regulator” concept in human tumours and the “bottleneck” hypothesis of master regulator function in glioma.

This talk is part of the Cambridge Oncology Seminar Series series.

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