Penny Peck

Name:	Penny Peck
Affiliation:	University of Cambridge
E-mail:	(only provided to users who are logged into talks.cam)
Last login:	Mon Mar 25 16:07:06 +0000 2024

Public lists managed by Penny Peck

• MRC Mitochondrial Biology Unit Seminars

Talks given by Penny Peck

Obviously this only lists talks that are listed through talks.cam. Furthermore, this facility only works if the speaker's e-mail was specified in a talk. Most talks have not done this.

Talks organised by Penny Peck

This list is based on what was entered into the 'organiser' field in a talk. It may not mean that Penny Peck actually organised the talk, they may have been responsible only for entering the talk into the talks.cam system.

• Unbiased Genetic Screening to find Modifiers of Mitochondria in Neurons
• Signal Switches at the Mitochondrial Import Machinery
• Title to be confirmed
• Title to be confirmed
• Molecular mechanisms of reversible infantile mitochondrial diseases
• Tissue-specific aspects of heteroplasmy in human mitochondrial DNA
• Spatial organisation of mitochondrial gene expression: the role of mitochondrial RNA granules
• Title to be confirmed
• Revealing mitochondrial function by reading mtDNA mutation patterns
• Whole genome sequencing for diagnosis and discovery of mitochondrial diseases
• Organelle-specific subcellular delivery using miothcondria-penetrating peptides
• Stress-induced dynamic regulation of mitochondrial STAT3 and its association with cyclophilin D reduce mitochondrial ROS production
• Title to be confirmed
• A role for actin in mitochondrial division: effects across two membranes
• Drosophila models of mitochondrial toxic signals
• The 6th Annual Sir John Walker Lecture, 'Genomics approaches to mitochondrial physiology and disease'
• m1A modification of nuclear- and mitochondria-encoded mRNA: Rare, dynamic and potent
• Molecular wiring of a mitochondrial translation feedback loop
• Isotope tracing, flux analysis and the metabolic phenotypes of transformed cells
• Title to be confirmed
• AMPK - a sensor of cellular energy and glucose availability, and a key interface between mitochondria and their host cell
• Exploring molecular mechanisms in biological energy conversion
• Title to be confirmed
• Title to be confirmed
• Title to be confirmed
• Oxidative stress, ROS and free radicals - using nitroxide antioxidants for detection and protection
• Title to be confirmed
• The 5th Annual Sir John Walker Lecture, "The mitochondrial calcium uniporter: molecular identity and physiological role"
• Eating your mitochondria: why, when and where?
• Title to be confirmed
• "There's something wrong with my MAM; the ER-mitochondria axis and neurodegenerative diseases"
• Title to be confirmed
• Title to be confirmed
• Mitochondrial disease research at Queen Square - past, present and future
• Title to be confirmed
• Title to be confirmed
• Title to be confirmed
• Structure, Biology and Therapeutic Potential of Novel ER Located Growth Factors
• Using electron microscopy to study mitochondrial ribosomes
• Biogenesis of iron-sulfur proteins in eukaryotes: Mitochondria, mitoses, mechanisms, DNA maintenance, and maladies
• Adaptations mediated by a mitochondrial UPR
• Title to be confirmed
• Title to be confirmed
• Title to be confirmed
• Evolution and coordination of the mitochondrial protein synthesis machinery
• The transparent editorial process, data reproducibility and research integrity at EMBO Press
• Natural and engineered redox signaling relays inside and outside mitochondria
• Regulation of mitochondrial function by stearic acid
• Mitochondrial optic neuropathies and beyond: the common theme of mitochondrial dynamics and mechanistic insights
• The Wanderings of a Free Radical
• Mitochondrial Proteases and Neurodegeneration
• Title to be confirmed
• Intermediate steps of the respirasome assembly pathway: Gaining insight into the structural interdependences among respiratory chain complexes
• The exome sequencing identified the mutation in YARS2 Nuclear modifier genes for the phenotypic manifestation of Leber's hereditary optic neuropathy-associated mitochondrial DNA mutation
• ROS produced via Reverse Electron Transport at respiratory complex I regulates mitochondrial turnover and lifespan
• Our journey towards mouse models of mitochondrial DNA disease
• CoQ Redox Status is a Metabolic Sensor
• Between life and death: A dual function for the mitochondrial F-ATP synthase
• Mitigating mitochondrial mutational meltdown
• Mitochondria at work: Regulation of skeletal muscle mitochondria function during exercise
• The Third Annual Sir John Walker Lecture: "HUMAN OBESITY: CAUSES AND CONSEQUENCES"
• Mitochondrial remodelling during embryonal cancer stem cell differentiation
• Molecular and pharmacological regulation of cell mitophagy
• Molecular regulation of receptor-mediated mitochondrial autophagy and its role in aging related diseases
• TBA
• TBA
• The alternative oxidase: a novel therapeutic target for the treatment of trypanosomiasis, cryptosporidiosis and candidiasis
• TBA
• The structure and mechanism of mitochondrial complex I
• Molecular strategies for monitoring and controlling mitochondria
• Targeted nanoparticles for mitochondrial medicine
• Markus: From its origins to the modern metabolic network. Jakob: Overcoming the yeast ‘petite’ phenotype: Insights into metabolic adaptations to mitochondrial genome loss
• tRNase ZL (ELAC 2) is central to eukaryotic pre-tRNA 3' end maturation
• Mitochondrial evolution: genome vs proteome
• Structure and mechanism of mitochondrial cytochrome c oxidases
• Tracking proton pathways in the heme-copper oxidase superfamily: Insights from all-atom simulations
• The role of mammalian CLpP protease beyond mitochondrial unfolded protein response
• Biogenesis of mitochondrial membrane protein complexes
• Who is talking with who in hte OXPHOS system, and how?
• Mitochondrial complex I assembly; regulating the metabolic regulator
• Title to be confirmed
• Mitochondrial optic neuropathies as a multifaceted model for neurodegeneration: a reappraisal
• Translation machinery in mitochondria – from structure towards clinic
• The 2nd Annual Sir John Walker Lecture: "Bioenergetic constraints on the evolution of cells"
• Mitochondria and hypoxia/HIF signalling
• UCP2 regulates the oxidation of glucose and glutamine by exporting C4 metabolites out of mitochondria
• Exome sequencing in the paediatric mitochondrial clinic
• Modeling GBA1-associated Parkinson's disease using engineered pluripotent stem cells
• Translational bioenergetics in diabetes; from the beta cell to chronic kidney disease
• Metabolite damage and its repair or pre-emption
• 'Pathways to mitochondrial dysfunction in neurodegeneration'
• 'Coping with cellular stress: the mitochondrial way'
• Mitochondrial gene expression in humans: a tale of two tails
• p73 regulates cancer cell survival and metabolism
• Molecular mechanisms and therapeutic approaches to childhood mitochondrial diseases
• Alternative respiratory enzymes: a route to therapy for mitochondrial disorders
• Insights into mitochondrial disease using polymerase gamma disease as a paradigm
• Physiological and pharmacological activation of AMP-activated protein kinase
• Analysis of Parkinson's disease genes using Drosophila: mitophagy and axonal transport
• Molecular mechanisms of mitochondrial genetic disease
• The mitochondrial m-AAA protease and neurodegeneration
• TBA
• TBA
• Reading the (mitochondrial) signals to understand tissue-specific pathology
• THE INAUGURAL SIR JOHN WALKER LECTURE: 'A Mitochondrial Etiology of Metabolic and Degenerative Diseases, Cancer and Aging'
• Posttranscriptional regulation of mitochondrial gene expression
• 'Mitochondria in cell fate reprogramming: from mechanisms to disease investigation'
• 'The mitochondrial permeability transition pore: A mystery solved?'
• 'Pantothenate kinase-associated neurodegeneration: investigations of a Pank2 KO mouse model and development of new neuronal cellular systems'
• Regulation of complex I amount: molecular mechanism
• Supercomplex assembly determines electron flux in the mitochondrial electron transport chain
• The power and limits of NGS strategies to address mitochondrial disorders
• Protein structure determination using X-ray lasers
• 'Mitochondrial dysfunction modifies physiological signaling and contributes to pathogenesis'
• 'Genetics and biotechnological applications at high temperature'
• 'Adapting to unfolded protein load in the endoplasmic reticulum'
• Mitochondrial transcription and its regulation
• 'Mitochondria: from pyruvate import to RNA processing'
• Exome sequencing in mitochondrial disorders as a tool to advance our understanding of mitochondrial physiology
• Metabolism and cancer: why should we care?
• The metabolic transformation of cancer cell
• Physio-pathology of mitochondrial complex III assembly
• Mitochondria and the cytoskeleton – matters of life and death in the face of stress
• 'Co-operative switching, turnover, and mechano-chemistry in a biological macromolecular complex'
• 'Exploitation of host mitochondria by human pathogenic Neisseria'
• 'Neurodegenerative alpha-synucleinopathies'
• 'Parkinson's disease: is it all mitochondrial?'
• 'Coupling of Na+/H+ transfer to the rotary mechanism of ATP synthase'
• 'The making of mitochondrial complex I: regulation of the biogenesis of a key metabolic enzyme'
• 'Clustering of Alpers disease mutations and catalytic defects in biochemical variants'
• 'Atomic structures of the eukaryotic ribosome and implications for the initiation of protein synthesis'
• ‘Multiscale simulations of membrane proteins and their interactions’
• 'Multiscale Simulations of Membrane Proteins and their Interactions'
• 'Neurodegenerative tauopathies'
• 'Evolutionary and functional relationships between eukaryotes and mitochondria'
• 'Metabolic clocks'
• 'Synaptic damage in neurodegeneration'
• 'Three-dimensional electron microscopy of cells and viruses at molecular resolution: From structure to mechanism'
• 'The respiratory complex I: substrate binding sites and mechanism of proton translocation'
• 'PGC-1α in muscular and neurodegenerative disorders'
• 'ATP-sensitive potassium channels and neonatal diabetes: a treatable channelopathy'
• 'Molecular characterization of the mitochondrial calcium uniporter'
• 'UCP1 and the other "uncoupling proteins": regulation and significance'
• 'The mitochondria's role in autophagy and cell cycle control'
• 'L-form bacteria, mitochondria, and the origins of cellular life'
• Mitochondrial Reactive Oxygen Species: Signals or Stresses?
• Mitochondrial optic neuropathies as a multifaced model for neurodegeneration
• 'Mitochondrial release factors: a family or just good friends?'
• 'Imaging mitochondrial function in the intact heart'
• 'What mitochondria learned from their bacterial ancestors: Oxidation-driven protein folding'
• 'Disulfide bond formation in biogenesis of mitochondrial proteins'
• 'Modelling and analysis of diabetes-related metabolic processes'