Mitochondria and the cytoskeleton – matters of life and death in the face of stress

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• Dr Campbell Gourlay, University of Kent
• Wednesday 10 October 2012, 15:00-16:00
• Sackler Lecture Theatre (Level 7) Wellcome Trust/MRC Building, Addenbrooke's Site.

If you have a question about this talk, please contact Penny Peck.

Cell survival in the face of stress relies upon linking the perception of change to appropriate downstream responses. The actin cytoskeleton, in addition to its better known role as a cellular scaffold, is emerging as an important co-ordinator of stress perception and response. Of particular note appears to be the conserved role that actin plays in regulating mitochondrial function in response to a variety of stresses. This relationship can be utilised to engage the mitochondria within newly discovered retrograde signalling pathways, or to initiate apoptosis. Using the model eukaryote S. cerevisae we have identified new pathways that link the health of both the actin cytoskeleton and the mitochondria to environmental responses that determine cell fate.

This talk is part of the MRC Mitochondrial Biology Unit Seminars series.

This talk is included in these lists:

• All Talks (aka the CURE list)
• CamBridgeSens
• Cambridge talks
• Life Science Interface Seminars
• MRC Mitochondrial Biology Unit Seminars
• Sackler Lecture Theatre (Level 7) Wellcome Trust/MRC Building, Addenbrooke's Site
• Trust & Technology Initiative - interesting events

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