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'Modelling and analysis of diabetes-related metabolic processes'

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If you have a question about this talk, please contact Penny Peck.

The relationship between gene mutations and disease is a complex one. As we acquire more information it is becoming increasingly difficult for individual biologists to maintain an overview of the structure and function of the systems they work on. To overcome this there is a need for computational models that can aid the bench scientist both in the design of experiments and understanding how well current knowledge describes the system at hand. As a first step towards this we have constructed models of molecular systems that play a part in Type II diabetes and mitochondrial function. I will present an overview of these models including an analysis of the evolution of the core biochemical processes leading from glucose breakdown to ATP production in pancreatic β-cells.

This talk is part of the MRC Mitochondrial Biology Unit Seminars series.

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