Gene silencing in plant development and disease resistance: lessons from tomato

Add to your list(s) Download to your calendar using vCal

• Zhengming Wang, Baulcombe Group
• Thursday 12 January 2017, 13:00-13:30
• Department of Plant Sciences, Large Lecture Theatre.

If you have a question about this talk, please contact sl750.

Gene silencing downregulates gene expression, which can occur during either transcription (TGS) or post transcription (PTGS). TGS , mainly through epigenetic modifications of target genes, plays an important role in genome stability. However, PTGS , mainly through target mRNA cleavage or translation inhibition, is important for gene regulation and antiviral defence. We have recently used CRISPR /Cas9 to create tomato mutants of genes involved in TGS and maintenance of Histone3 lyscine9 di-methylation (H3K9me2). Phenotyping and molecular analysis of these mutants reveal that H3K9me2 plays a crucial role in tomato development and reproduction. In addition, we identified a feedback regulatory loop of Dicer-like (DCL) 2 and miR6026, which deepens our understanding of how antiviral PTGS responds to virus infection in tomato.

This talk is part of the Plant Sciences Departmental Seminars series.

This talk is included in these lists:

• All Talks (aka the CURE list)
• Biology
• Biology
• CambPlants Hub
• Cambridge Global Food Security
• Cambridge Global Food Security
• Department of Plant Sciences, Large Lecture Theatre
• Interesting talks- 1st try
• Life Sciences
• Life Sciences
• ME Seminar
• Plant Sciences Departmental Seminars
• Reception - Plant Sciences
• ji247's list
• my_list
• other talks

Note that ex-directory lists are not shown.