The brain on stress - Mechanisms underlying increases risk to develop psychopathologies

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• Professor Carmen Sandi, Director of the Laboratory of Behavioural Genetics, Brain and Mind Institute, EPFL, Lausanne
• Thursday 03 March 2016, 15:30-16:30
• Lecture Theatre, MRC Cognition and Brain Sciences Unit, Chaucer Road.

If you have a question about this talk, please contact Deborah McSkimming.

Stress is an important modulator of brain function, behaviour and cognition, and can trigger or exacerbate psychopathologies. I will present findings showing that both stress during early life and chronic stress at adulthood leads to alterations in depression- and anxiety-like behaviours, as well as dysfunctional behaviours in the social domain. Importantly, individual differences in stress effects are largely related to the personality trait anxiety. Despite recent interest in identifying the mediating mechanisms whereby highly anxious individuals eventually develop these psychopathologies, current understanding is scarce. I will present recent evidence that highlights brain energy metabolism as a relevant mediating mechanism.

This talk is part of the Chaucer Club series.

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