Self-Assembled DNA Nanosystems for Energy and Electron Transfer Applications

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• Professor Bo Albinsson, Chalmers University of Technology
• Tuesday 10 November 2015, 14:30-15:30
• Kapitza Building Seminar Room, Cavendish Laboratory, Department of Physics.

If you have a question about this talk, please contact Stuart Higgins.

DNA has the possibility to self-assemble into predefined 2 and 3-dimensional objects, with a spatial resolution on the sub-nm level.(1) The DNA constructs can easily be made with compositions and shapes defined at the atomic level in molar amounts in bulk phase, as compared to normal lithographic techniques in which objects are made one by one with much lower spatial resolution. These features have made DNA an interesting building block in bottom-up nanotechnology. In this presentation I will describe how we systematically have developed 1 and 2-dimensional DNA constructs for the precise positioning of components involved in photoinduced electron transfer reactions.(2,3) Linear and branched DNA molecules have been functionalized with lipophilic porphyrins that act as anchors in liposomes and on supported membranes.(4,5) The porphyrin anchors, furthermore, undergo photoinduced electron transfer reactions with electron acceptors that reside in the membrane. The DNA , which resides in the water phase, can in turn act as a scaffold for antennas undergoing multi-step energy transfer reactions.(6-8) With this flexible approach we can self-assemble a wide variety of complex energy transfer and redox components with the aim to produce a predetermined molecular pattern forming the basis for novel lithographic applications.

References (1) Seeman, N. C. Annu. Rev. Biochem.. 79 (2010) 65-87. (2) Börjesson, K.; Tumpane, J.; Ljungdahl, T.; Wilhelmsson, L. M.; Nordén, B.; Brown, T.; Mårtensson, J.; Albinsson, B. J. Am. Chem. Soc. 131 (2009) 2831-2839. (3) Börjesson, K.; Wiberg, J.; El-Sagheer, A. H.; Ljungdahl, T.; Mårtensson, J.; Brown, T.; Nordén, B.; Albinsson, B. ACS Nano 4 (2010) 5037-5046. (4) Woller, J. G.; Börjesson, K.; Svedhem, S.; Albinsson, B. Langmuir 28 (2012) 1944-1953. (5) Börjesson, K.; Lundberg, E. P.; Woller, J. G.; Nordén, B.; Albinsson, B. Angew. Chem. Int. Ed. 50 (2011) 8312-8315. (6) Albinsson, B. Nature Chem. 3 (2011) 269-270. (7) Hannestad, J. K.; Sandin, P.; Albinsson, B. J. Am. Chem. Soc. 130 (2008) 15889-15895. (8) Woller, J. G.; Hannestad, J. K.; Albinsson, B. J. Am. Chem. Soc. 135 (2013) 2759-2768. (9) Börjesson, K.; Woller, J. G.; Parsa, E.; Mårtensson, J.; Albinsson, B. Chem. Commun. 48 (2012) 1793-1795.

This talk is part of the Optoelectronics Group series.

This talk is included in these lists:

• All Cavendish Laboratory Seminars
• All Talks (aka the CURE list)
• Cambridge Infectious Diseases
• Centre for Health Leadership and Enterprise
• Featured lists
• Kapitza Building Seminar Room, Cavendish Laboratory, Department of Physics
• ME Seminar
• Neurons, Fake News, DNA and your iPhone: The Mathematics of Information
• Optoelectronics Group
• School of Physical Sciences
• Thin Film Magnetic Talks
• few29

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