Paramutation in tomato

Add to your list(s) Download to your calendar using vCal

• Quentin Gouil, 3rd yr grad
• Friday 01 May 2015, 12:00-12:30
• Sainsbury Laboratory.

If you have a question about this talk, please contact Megan Cooper.

Paramutation is the copying of an allele’s epigenetic state onto the other allele at the same locus. Examples of paramutation are rare in plants, and even rarer in animals. The historic sulfurea paramutation in tomato (Hagemann 1958) leads to a yellowing of the leaves, but the causal locus is still unknown. I identify a candidate gene for sulfurea through mRNA-Seq and virus-induced gene silencing. The sulfurea phenotype was generated through mutagenesis, but paramutation can also occur between natural epialleles. I describe the first natural example of paramutation in tomato at a locus termed H06 , following hybrididation of the cultivated M82 and its wild relative Solanum pennellii, which highlights the importance of the RNA silencing machinery in this process. Finally, genome-wide analysis of methylation in the introgression lines suggests that paramutation is not exceedingly rare, and could play a role in the transgressive phenotypes of hybrids.

This talk is part of the Plant Sciences Departmental Seminars series.

This talk is included in these lists:

• All Talks (aka the CURE list)
• Biology
• Biology
• CambPlants Hub
• Cambridge Global Food Security
• Cambridge Global Food Security
• Interesting talks- 1st try
• Life Sciences
• Life Sciences
• ME Seminar
• Plant Sciences Departmental Seminars
• Reception - Plant Sciences
• Sainsbury Laboratory
• ji247's list
• my_list
• other talks

Note that ex-directory lists are not shown.