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Protein misfolding and disaggregation by chaperones

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If you have a question about this talk, please contact Sophie Mathias.

Professor Helen Saibil FRS is Bernal Professor of Structural Biology at Birkbeck, University of London.

Her group studies the operation of macromolecular machines using three-dimensional electron microscopy. Their research projects are in the areas of molecular chaperones and assisted protein folding/unfolding, misfolding into amyloid, and protein refolding in membrane pore formation. They use single particle cryo-electron microscopy and electron tomography to study isolated complexes, irregular assemblies and cell sections.

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