University of Cambridge > > Plant Sciences Research Seminars > Marchantia polymorpha: A model for developmental biology and a novel chassis for synthetic biology

Marchantia polymorpha: A model for developmental biology and a novel chassis for synthetic biology

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Synthetic Biology of eukaryotic systems is highly challenging and there are very few established standards for their manipulation. Liverworts are descendants of the most ancient terrestrial plants. In particular, the Liverwort Marchantia polymorpha (Marchantia) is a promising system for developmental biology , a chassis for synthetic biology and also a test bed for reverse engineering plant morphogenesis. This is due to its genetic simplicity with respect to higher plants (haploid, low genetic redundancy); ease of culture and transformation; modular growth phases and optimal size for microscopy. This project provides a description of the early stages of development of this plant through optical microscopy and 3D reconstruction techniques. Mapping the developmental stages of Marchantia is the first step towards constructing a standardised framework for manipulation of the system. The presented results include optimised techniques for 3D imaging and segmentation of Marchantia cells. A microscopy map of Marchantia development will feed directly into a dynamical model of plant morphogenesis and help identify potential genetic markers for engineering the system

This talk is part of the Plant Sciences Research Seminars series.

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