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"Identifying lipid signals in normal and diseased cells"

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If you have a question about this talk, please contact Dr Karyn Megy.

Lipids are key components of all cellular membranes, additionally they are an essential part of our diet, however, they are not simply static entities providing cell structure and energy stores. A range of lipids act as intra-and inter-cellular signals controlling cell functions such as migration, secretion, cell proliferation and survival and loss of regulation of the generation or removal of signalling lipids occurs in a range of diseases such as cancer and some autoimmune disorders. Not all lipid species within a class of lipids acts as a signal, for instance the often quoted importance of polyunsaturated versus unsaturated fats in our diets has a biochemical basis in determining whether certain lipids are signals or stores. Recent advances in mass spectroscopy has allowed analysis leading to a greater understanding of the roles of these lipid signals and points to novel therapeutic targets and the possibility of lipids as biomarkers.

This talk is part of the Cambridge University Biological Society series.

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