University of Cambridge > Talks.cam > ym354's list > Organic Bioelectronic Interfaces Based on Crystalline PEDOT:PSS Films, Microfibers, and Fibrillar Hydrogel

Organic Bioelectronic Interfaces Based on Crystalline PEDOT:PSS Films, Microfibers, and Fibrillar Hydrogel

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In this research, we developed organic bioelectronic interfaces based on highly crystalline poly(3,4-ethylenedioxythiophene):polystyrene sulfonate (PEDOT:PSS) films or microfibers to overcome the trade-off between electrical/electrochemical performance and long-term stability in water. Crystalline PEDOT :PSS films exhibit excellent electrical/electrochemical/optical properties, long-term aqueous stability, and good biocompatibility for primarily cultured cardiomyocytes and neurons over several weeks. Furthermore, they are successfully employed for high-performance multi-electrode arrays (MEAs) to record and stimulate the electrophysiological activities of primarily cultured cardiomyocytes and chicken retinae tissues. In parallel, we successfully developed crystalline PEDOT :PSS microfibers and PEDOT :PSS-incorporated fibrillar hydrogels for single-strand wearable electrochemical transistors and 3-D neuronal network reconstruct, respectively, for novel bioelectronic interfaces.

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