Modelling cortical gain in autism (without neuroimaging)

Add to your list(s) Download to your calendar using vCal

• Dr Rebecca Lawson, Sir Henry Dale Fellowship, Affiliated Lecturer Department of Psychology, University of Cambridge
• Friday 05 October 2018, 16:30-17:30
• Ground Floor Lecture Theatre, Department of Psychology.

If you have a question about this talk, please contact Louise White.

Behavioural and neural measures of visual processing indicate that perception is strongly influenced by the recent sensory past. Such context sensitive sensory responses arise from gain control mechanisms, where estimates of variability scale the driving neural responses to sensory input. Gain control can operate locally, in the form of divisive normalisation (reflecting inhibitory interactions between functionally related cell populations) or distally, in the form of precision weighting (reflecting the action of feedback connections and neuromodulators). In this talk I will first offer an account of how these mechanisms provide a computational and neurobiological framework to interrogate the notion of ‘context insensitive’ perception in autism. I will then go on to present some recent data examining how visual processing in autistic adults is contextualised by the recent sensory history. Using computational modelling approaches, we find that local normalisation of sensory responses occurs typically in autism. However, we find evidence for altered noradrenergic regulation of how sensory processing is contextualised by learned expectations.

This talk is part of the Zangwill Club series.

This talk is included in these lists:

• All Talks (aka the CURE list)
• Biology
• Cambridge Forum of Science and Humanities
• Cambridge Language Sciences
• Cambridge Neuroscience Seminars
• Cambridge talks
• Chris Davis' list
• Department of Psychiatry talks stream
• Featured lists
• Ground Floor Lecture Theatre, Department of Psychology
• Guy Emerson's list
• Interested Talks
• Life Science
• Life Sciences
• Neuroscience
• Neuroscience Seminars
• Neuroscience Seminars
• Psychology talks and events
• Stem Cells & Regenerative Medicine
• Yishu's list
• Zangwill Club
• dh539
• kt532's list
• my List

Note that ex-directory lists are not shown.