Functionalized Antibodies

Add to your list(s) Download to your calendar using vCal

• Professor Akira Harada, Osaka University, Japan
• Thursday 25 October 2012, 11:30-12:30
• BP Institute.

If you have a question about this talk, please contact Sian Bunnage.

Monoclonal antibodies have been prepared against porphyrins, rhodium phosphine complexes, and binaphthyl derivatives. The monoclonal antibody-porphyrin complex was found to catalyze some redox reactions as enzymes do. In addition, the antibody for porphyrin-acceptor was found to bind porphyrin and when the complex was irradiated by visible light in the presence of viologen and hydrogenase or platinum colloid, hydrogen gas was evolved from aqueous solution. The efficiency is the highest in the protein-porphyirin systems. The monoclonal antibody against rhodium phosphine complex was found to bind the complex and the compound was found to catalyze hydrogenation of amino acid precursors to give almost 100% L-amino acid, although the rhodium phosphine complex is achiral. This is due to the second-sphere coordination effects.

This talk is part of the BP Lectures 2012 series.

This talk is included in these lists:

• All Talks (aka the CURE list)
• BP Institute
• BP Lectures 2012
• Cambridge Energy Seminars
• Department of Chemistry
• Featured lists
• NanoDTC Energy Materials Talks
• School of Physical Sciences
• history

Note that ex-directory lists are not shown.