Setting sample size for common designs when evaluating interventions and biomarkers

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• Professor Toby Prevost, Kings College London
• Tuesday 24 April 2012, 14:00-15:00
• Large Seminar Room, 1st Floor, Institute of Public Health, University Forvie Site, Robinson Way, Cambridge.

If you have a question about this talk, please contact Dr Jack Bowden.

Note the earlier than usual start time

Setting the sample size for health intervention trials typically requires interaction between statisticians and health professionals. In this talk I will bring together some of the methods for sample size calculation to show how the core formulae can help the statistician to improve the inputs and outputs. The second part of the talk consists of an introduction to biomarkers and appropriate late phase designs for their evaluation, with a worked example to set the sample size of a two-stage early-phase biomarker study with local health professionals.

This talk is part of the MRC Biostatistics Unit Seminars series.

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